AC T05437
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ID T05437
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DT 21.02.2003 (created); sth.
DT 19.02.2014 (updated); msr.
CO Copyright (C), QIAGEN.
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FA ESE-1a
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SY E74 like factor 3; ELF3; EPR-1; ERT; ESE-1; ESX.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005118 ELF3; HGNC: ELF3.
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CL C0016; ETS; 3.5.2.4.2.1.
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SZ 348 AA; 39.4 kDa (calc.).
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SQ MAATCEISNIFSNYFSAMYSSEDSTLASVPPAATFGADDLVLTLSNPQMSLEGTEKASWL
SQ GEQPQFWSKTQVLDWISYQVEKNKYDASAIDFSRCDMDGATLCNCALEELRLVFGPLGDQ
SQ LHAQLRDLTSSSSDELSWIIELLEKDGMAFQEALDPGPFDQGSPFAQELLDDVSTAGTGA
SQ SRSSHSSDSGGSDVDLDPTDGKLFPSDGFRDCKKGDPKHGKRKRGRPRKLSKEYWDCLEG
SQ KKSKHAPRGTHLWEFIRDILIHPELNEGLMKWENRHEGVFKFLRSEAVAQLWGQKKKNSN
SQ MTYEKLSRAMRYYYKREILERVDGRRLVYKFGKNSSGWKEEEVLQSRN
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SC translated from EMBL #U73844
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FT 48 132 
PF02198; Sterile alpha motif (SAM)/Pointed domain.
FT 48 132 
SM00251; SAM2_3.
FT 63 137 
POINTED domain [2].
FT 221 233 
PF02178; AT_hook.
FT 249 331 
ETS domain [2].
FT 249 334 
PF00178; Ets-domain.
FT 249 336 
SM00413; etsneu2.
FT 250 332 
PS50061; ETS_DOMAIN_3.
FT 260 322 
PS50140; HSF_ETS.
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SF splice variant of ETS factor ESE-1 T05448 [1];
SF contains two putative DNA binding domains, an ETS domain and A/T hook domain [1];
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CP exclusively expressed in epithelial cells [1].
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FF critical regulator of epithelial cell differentiation [1];
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MX M02055 V$ESE1_02.
MX M01214 V$ESE1_Q3.
MX M07285 V$ESE1_Q6.
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DR TRANSPATH: MO000054231.
DR EMBL: U73844; U73844.
DR UniProtKB: P78545-2;
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RN [1]; RE0022526.
RX PUBMED: 9234700.
RA Oettgen P., Alani R. M., Barcinski M. A., Brown L., Akbarali Y., Boltax J., Kunsch C., Munger K., Libermann T. A.
RT Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family.
RL Mol. Cell. Biol. 17:4419-4433 (1997).
RN [2]; RE0022459.
RX PUBMED: 10644770.
RA Kas K., Finger E., Grall F., Gu X., Akbarali Y., Boltax J., Weiss A., Oettgen P., Kapeller R., Libermann T. A.
RT ESE-3, a novel member of an epithelium-specific ets transcription factor subfamily, demonstrates different target gene specificity from ESE-1.
RL J. Biol. Chem. 275:2986-2998 (2000).
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//