AC T05811
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ID T05811
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DT 12.01.2004 (created); ate.
DT 04.03.2004 (updated); oke.
CO Copyright (C), QIAGEN.
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FA HSF4b
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SY heat shock (transcription) factor 4; HSF 4b; HSF-4b.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009110 Hsf4.
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CL C0050; HSF; 3.4.1.0.3.2.
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SZ 492 AA; 53.3 kDa (calc.).
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SQ MQEAPAALPTEPGPSPVPAFLGKLWALVGDPGTDHLIRWSPSGTSFLVSDQSRFAKEVLP
SQ QYFKHSNMASFVRQLNMYGFRKVVSIEQGGLLRPERDHVEFQHPSFVRGREQLLERVRRK
SQ VPALRGDDSRWRPEDLSRLLGEVQALRGVQESTEARLQELRQQNEILWREVVTLRQSHSQ
SQ QHRVIGKLIQCLFGPLQTGPSSTGAKRKLSLMLDEGSACSASAKFNACPVSGALLQDPYF
SQ IQSPLPETTLGLSPHRARGPIISDIPEDSPSPEGHRLSPSGGCRRVKGLALLKEEPASPG
SQ GDGEAGLALAPNECDFCVTAPPPLPVAVVQAILEGKGSYSPEGPRSVQQPEPRGPREVPD
SQ RGTLGLDRGNRSPESLLPPMLLRPAPETLEPVAPVDVLGPSLHGREWTLMDLDMELSLMQ
SQ PLAPETDEAELTVKELNSSGVGKDHTLGTPLMLDVQADLEGAALSVPGALTLYNVTESNA
SQ SYLDPGASPSSP
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SC translated from EMBL #AB029349
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FT 16 120 
SM00415; HSF.
FT 18 211 
PF00447; HSF-type DNA-binding.
FT 20 87 
PS50140; HSF_ETS.
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SF isoform 4b of mouse HSF 4;
SF currently two isoforms are known (4a T05810, 4b) [1];
SF protein is multimeric (trimeric) under nonstress conditions [1];
SF HSF-4 (both isoforms: a and b) lacks the carboxy-terminal heptad repeat of hydrophobic amino acids (HR-C) necessary for the inhibition of trimer formation (all vertebrates) [1];
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DR TRANSPATH: MO000041091.
DR EMBL: AB029349;
DR UniProtKB: Q9R0L1-1;
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RN [1]; RE0017257.
RX PUBMED: 10488131.
RA Tanabe M., Sasai N., Nagata K., Liu X. D., Liu P. C., Thiele D. J., Nakai A.
RT The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing
RL J. Biol. Chem. 274:27845-27856 (1999).
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