TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T05841 XX ID T05841 XX DT 04.02.2004 (created); elf. DT 16.11.2007 (updated); bch. CO Copyright (C), QIAGEN. XX FA OLIG2 XX SY Basic helix-loop-helix protein class B 1; BHLHB1; OLIG2; oligodendrocyte lineage transcription factor 2; PRKCBP2; Protein kinase C binding protein 2; RACK17. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G009151 OLIG2; HGNC: OLIG2. XX CL C0010; bHLH; XX CP mature oligodendrocytes [2]. XX FF BHLHB1 expression normally restricted to neural tissues [1]; FF specification of oligodendrocytes and motoneurons during vertebrate embryogenesis [2]; XX DR TRANSPATH: MO000039156. DR UniProtKB: Q13516; XX RN [1]; RE0023800. RX PUBMED: 10737801. RA Wang J., Jani-Sait S. N., Escalon E. A., Carroll A. J., de Jong P. J., Kirsch I. R., Aplan P. D. RT The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene. RL Proc. Natl. Acad. Sci. USA 97:3497-3502 (2000). RN [2]; RE0025491. RX PUBMED: 15604411. RA Arnett H. A., Fancy S. P., Alberta J. A., Zhao C., Plant S. R., Kaing S., Raine C. S., Rowitch D. H., Franklin R. J., Stiles C. D. RT bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS. RL Science 306:2111-2115 (2004). XX //