AC T05841
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ID T05841
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DT 04.02.2004 (created); elf.
DT 16.11.2007 (updated); bch.
CO Copyright (C), QIAGEN.
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FA OLIG2
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SY Basic helix-loop-helix protein class B 1; BHLHB1; OLIG2; oligodendrocyte lineage transcription factor 2; PRKCBP2; Protein kinase C binding protein 2; RACK17.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009151 OLIG2; HGNC: OLIG2.
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CL C0010; bHLH; 1.2.3.4.14.
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CP mature oligodendrocytes [2].
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FF BHLHB1 expression normally restricted to neural tissues [1];
FF specification of oligodendrocytes and motoneurons during vertebrate embryogenesis [2];
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DR TRANSPATH: MO000039156.
DR UniProtKB: Q13516;
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RN [1]; RE0023800.
RX PUBMED: 10737801.
RA Wang J., Jani-Sait S. N., Escalon E. A., Carroll A. J., de Jong P. J., Kirsch I. R., Aplan P. D.
RT The t(14;21)(q11.2;q22) chromosomal translocation associated with T-cell acute lymphoblastic leukemia activates the BHLHB1 gene.
RL Proc. Natl. Acad. Sci. USA 97:3497-3502 (2000).
RN [2]; RE0025491.
RX PUBMED: 15604411.
RA Arnett H. A., Fancy S. P., Alberta J. A., Zhao C., Plant S. R., Kaing S., Raine C. S., Rowitch D. H., Franklin R. J., Stiles C. D.
RT bHLH transcription factor Olig1 is required to repair demyelinated lesions in the CNS.
RL Science 306:2111-2115 (2004).
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