AC T05847
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ID T05847
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DT 05.02.2004 (created); oke.
DT 19.08.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA Erm
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SY ERM; ets variant 5; ets variant gene 5 (ets-related molecule); ETV5.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G009155 ETV5; HGNC: ETV5.
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CL C0016; ETS; 3.5.2.2.6.
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SF belongs to the PEA3/ER81 subfamily of the Ets factors [1];
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CP mRNA is expressed ubiquitously [1]; high in brain [2].
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FF PKA (protein kinase A) increases the transcriptional activity of Erm [2];
FF activator [1];
FF acts synergistically with c-Jun on a synthetic oligonucleotide containing both Ets and CRE sites [1];
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MX M02069 V$ERM_02.
MX M03983 V$ETV5_01.
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BS R69994.
BS R69996.
BS R69997.
BS R42148.
BS R14803.
BS R22325.
BS R22326.
BS R18127.
BS R18128.
BS R18130.
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DR TRANSPATH: MO000038600.
DR UniProtKB: P41161;
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RN [1]; RE0011273.
RX PUBMED: 7559555.
RA Nakae K., Nakjima K., Inazawa J., Kitaoka T., Hirano T.
RT ERM, a PEA3 subfamily of Ets transcription factors, can cooperate with c-Jun
RL J. Biol. Chem. 270:23795-23800 (1995).
RN [2]; RE0035423.
RX PUBMED: 11682477.
RA Baert J. L., Beaudoin C., Coutte L., de Launoit Y.
RT ERM transactivation is up-regulated by the repression of DNA binding after the PKA phosphorylation of a consensus site at the edge of the ETS domain.
RL J. Biol. Chem. 277:1002-1012 (2002).
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