AC T05987
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ID T05987
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DT 27.05.2004 (created); oke.
DT 03.02.2009 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA deltaFosB
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SY short variant of FosB.
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OS rat, Rattus norvegicus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G009541 Fosb.
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CL C0008; bZIP.
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SF identified as a nuclear activity in the rat frontal cortex cells [1];
SF may form heterodimers with JunD T05988 [1];
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CP frontal cortex cells [1].
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FF activator [1];
FF binds to AP-1 sites as a heterodimer with JunD T05988 [1];
FF glutamate receptor subunit (gene NMDAR1) is a physiological target for FosB in brain [1];
FF important for molecular and behavioral adaptations to motor seizures [1];
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IN T02197 JunD; rat, Rattus norvegicus.
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MX M00517 V$AP1_01.
MX M00924 V$AP1_Q2_01.
MX M00926 V$AP1_Q4_01.
MX M00925 V$AP1_Q6_01.
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DR TRANSPATH: MO000042230.
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RN [1]; RE0024330.
RX PUBMED: 9712664.
RA Hiroi N., Marek G. J., Brown J. R., Ye H., Saudou F., Vaidya V. A., Duman R. S., Greenberg M. E., Nestler E. J.
RT Essential role of the fosB gene in molecular, cellular, and behavioral actions of chronic electroconvulsive seizures.
RL J. Neurosci. 18:6952-6962 (1998).
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