AC T06371
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ID T06371
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DT 06.12.2004 (created); cch.
DT 11.11.2010 (updated); din.
CO Copyright (C), QIAGEN.
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FA iASPP
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SY inhibitor of ASPP protein.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G013628 PPP1R13L; HGNC: PPP1R13L.
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CL C0020; Rel; 6.1.2.2.1.1.
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SZ 828 AA; 89.1 kDa (cDNA) (calc.).
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SQ MDSEAFQSARDFLDMNFQSLAMKHMDLKQMELDTAAAKVDELTKQLESLWSDSPAPPGPQ
SQ AGPPSRPPRYSSSSIPEPFGSRGSPRKAATDGADTPFGRSESAPTLHPYSPLSPKGRPSS
SQ PRTPLYLQPDAYGSLDRATSPRPRAFDGAGSSLGRAPSPRPGPGPLRQQGPPTPFDFLGR
SQ AGSPRGSPLAEGPQAFFPERGPSPRPPATAYDAPASAFGSSLLGSGGSAFAPPLRAQDDL
SQ TLRRRPPKAWNESDLDVAYEKKPSQTASYERLDVFARPASPSLQLLPWRESSLDGLGGTG
SQ KDNLTSATLPRNYKVSPLASDRRSDAGSYRRSLGSAGPSGTLPRSWQPVSRIPMPPSSPQ
SQ PRGAPRQRPIPLSMIFKLQNAFWEHGASRAMLPGSPLFTRAPPPKLQPQPQPQPQPQSQP
SQ QPQLPPQPQTQPQTPTPAPQHPQQTWPPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVD
SQ EGPVARPLSPTRLQPALPPEAQSVPELEEVARVLAEIPRPLKRRGSMEQAPAVALPPTHK
SQ KQYQQIISRLFHRHGGPGPGGPEPELSPITEGSEARAGPPAPAPPAPIPPPAPSQSSPPE
SQ QPQSMEMRSVLRKAGSPRKARRARLNPLVLLLDAALTGELEVVQQAVKEMNDPSQPNEEG
SQ ITALHNAICGANYSIVDFLITAGANVNSPDSHGWTPLHCAASCNDTVICMALVQHGAAIF
SQ ATTLSDGATAFEKCDPYREGYADCATYLADVEQSMGLMNSGAVYALWDYSAEFGDELSFR
SQ EGESVTVLRRDGPEETDWWWAALHGQEGYVPRNYFGLFPRVKPQRSKV
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SC Swiss-Prot#Q8WUF5-1
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FF iASPP and iASPP-RAI inhibit p53-mediated apoptosis [1];
FF iASPP and iASPP-RAI inhibit p53-mediated apoptosis [1];
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IN T00671 p53; human, Homo sapiens.
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DR TRANSPATH: MO000044920.
DR EMBL: BC032298;
DR UniProtKB: Q8WUF5-1;
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RN [1]; RE0025202.
RX PUBMED: 15489900.
RA Slee E. A., Gillotin S., Bergamaschi D., Royer C., Llanos S., Ali S., Jin B., Trigiante G., Lu X.
RT The N-terminus of a novel isoform of human iASPP is required for its cytoplasmic localization.
RL Oncogene 23:9007-9016 (2004).
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