AC T08293
XX
ID T08293
XX
DT 22.11.2005 (created); oke.
DT 15.06.2010 (updated); jig.
CO Copyright (C), QIAGEN.
XX
FA GATA-1
XX
SY EF1; EFgammaa; Eryf-1; Eryf1; GF-1; NF-E1; NF-E1a.
XX
OS chick, Gallus gallus
OC eukaryota; animalia; metazoa; chordata; vertebrata; aves; neornithes; neognathae; galliformes; phasianidae
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GE G000060 GATA1.
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CL C0003; CC (g).
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SZ 304 AA; 31.4 kDa (cDNA) (calc.), 38, 72 kDa (SDS)
XX
SQ MEFVALGGPDAGSPTPFPDEAGAFLGLGGGERTEAGGLLASYPPSGRVSLVPWADTGTLG
SQ TPQWVPPATQMEPPHYLELLQPPRGSPPHPSSGPLLPLSSGPPPCEARECVNCGATATPL
SQ WRRDGTGHYLCNACGLYHRLNGQNRPLIRPKKRLLVSKRAGTVCSNCQTSTTTLWRRSPM
SQ GDPVCNACGLYYKLHQVNRPLTMRKDGIQTRNRKVSSKGKKRRPPGGGNPSATAGGGAPM
SQ GGGGDPSMPPPPPPPAAAPPQSDALYALGPVVLSGHFLPFGNSGGFFGGGAGGYTAPPGL
SQ SPQI
XX
SC translated from EMBL: M26209
XX
FT 1 71 
transcription activation domain Act1 [5].
FT 84 121 
transcription activation domain Act2 [5].
FT 104 154 
SM00401; ZnF_GATA.
FT 104 159 
PS50114; GATA_ZN_FINGER_2.
FT 110 144 
PF00320; GATA zinc finger.
FT 158 216 
DNA binding domain [2].
FT 158 208 
SM00401; ZnF_GATA.
FT 158 211 
PS50114; GATA_ZN_FINGER_2.
FT 164 198 
PF00320; GATA zinc finger.
FT 234 304 
transcription activation domain Act3 [5].
XX
IN T19612 DRIP205; mouse, Mus musculus.
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MX M00075 V$GATA1_01.
MX M00126 V$GATA1_02.
MX M00127 V$GATA1_03.
MX M00128 V$GATA1_04.
MX M00346 V$GATA1_05.
MX M00347 V$GATA1_06.
MX M02004 V$GATA1_Q6.
MX M00203 V$GATA_C.
MX M00789 V$GATA_Q6.
XX
BS R02892.
BS R00513.
BS R00514.
BS R00515.
BS R00518.
BS R01944.
BS R01949.
BS R00536.
BS R00538.
BS R00539.
BS R08249.
BS R08250.
BS R08252.
BS R08253.
BS R03087.
BS R03093.
BS R02156.
BS R00507.
XX
DR TRANSPATH: MO000056586.
DR EMBL: M26209;
DR UniProtKB: P17678;
DR PDB: 1gat.
DR PDB: 1gau.
XX
RN [1]; RE0002989.
RX PUBMED: 1406646.
RA Yang H.-Y., Evans T.
RT Distinct roles for the two cGATA-1 finger domains
RL Mol. Cell. Biol. 12:4562-4570 (1992).
RN [2]; RE0013388.
RX PUBMED: 8332909.
RA Omichinski J. G., Clore G. M., Schaad O., Felsenfeld G., Trainor C., Appella E., Stahl S. J., Gronenborn A. M.
RT NMR structure of a specific DNA complex of Zn-containing DNA binding domain of GATA-1.
RL Science 261:438-446 (1993).
RN [3]; RE0013413.
RX PUBMED: 8446581.
RA Omichinski J. G., Trainor C., Evans T., Gronenborn A. M., Clore G. M., Felsenfeld G.
RT A small single-"finger" peptide from the erythroid transcription factor GATA-1 binds specifically to DNA as a zinc or iron complex.
RL Proc. Natl. Acad. Sci. USA 90:1676-1680 (1993).
RN [4]; RE0029104.
RX PUBMED: 11724781.
RA Crawford S. E., Qi C., Misra P., Stellmach V., Rao M. S., Engel J. D., Zhu Y., Reddy J. K.
RT Defects of the heart, eye, and megakaryocytes in peroxisome proliferator activator receptor-binding protein (PBP) null embryos implicate GATA family of transcription factors.
RL J. Biol. Chem. 277:3585-92 (2002).
RN [5]; RE0001771.
RX PUBMED: 2505081.
RA Kouzarides T., Ziff E.
RT Leucine zippers of fos, jun and GCN4 dictate dimerization specificity and thereby control DNA binding
RL Nature 340:568-571 (1989).
XX
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