AC T08334
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ID T08334
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DT 09.01.2006 (created); elf.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Sox-10
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SY early growth response 2; Egr-2; EGR2; Krox-20; KROX20; NGF1-B; sox-21; Sox10; Transcription factor SOX-10; Transcription factor SOX-M; Zfp-25; Zfp-6.
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OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G021491 Sox10.
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CL C0015; HMG.
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SZ 582 AA; 62.1 kDa (cDNA) (calc.).
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SQ RTGSPFQGEEEPFMEPSAAAQSVSAVQPGCLVVRIQAPSRQGSGLRLRAPQPLPPSPSAS
SQ LPSPELDRTPWDTVFHFLRTSPRLEERSEEVGVGLFTRTPAAGPGEAAEAAAAGSDMAEE
SQ QDLSEVELSPVGSEEPRCLSPGSAPSLGPDGGGGGSGLRASPGPGELGKVKKEQQDGEAD
SQ DDKFPVCIREAVSQVLSGYDWTLVPMPVRVNGASKSKPHVKRPMNAFMVWAQAARRKLAD
SQ QYPHLHNAELSKTLGKLWRLLNESDKRPFIEEAERLRMQHKKDHPDYKYQPRRRKNGKAA
SQ QGEAECPGGEAEQGGAAAIQAHYKSAHLDHRHPEEGSPMSDGNPEHPSGQSHGPPTPPTT
SQ PKTELQSGKADPKRDGRSLGEGGKPHIDFGNVDIGEISHEVMSNMETFDVTELDQYLPPN
SQ GHPGHVGSYSAAGYGLGSALAVASGHSAWISKPPGVALPTVSPPGVDAKAQVKTETTGPQ
SQ GPPHYTDQPSTSQIAYTSLSLPHYGSAFPSISRPQFDYSDHQPSGPYYGHAGQASGLYSA
SQ FSYMGPSQRPLYTAISDPSPSGPQSHSPTHWEQPVYTTLSRP
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SC translated from EMBL:AF017182
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FT 194 568 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 219 289 
SM00398; hmgende2.
FT 220 288 
PF00505; HMG (high mobility group) box.
FT 220 288 
PS50118; HMG_BOX_2.
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FF activator: ectopic expression of Sox-10 induces murine MBP G000555 and rat P0 G021489promoter activity in F10.9 cells non-treated with IL6RIL6 [2];
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IN T11270 Pax-3; human, Homo sapiens.
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MX M07338 V$SOX10_Q3.
MX M01131 V$SOX10_Q6.
MX M02116 V$SOX10_Q6_01.
MX M08899 V$SOX_Q4.
MX M01014 V$SOX_Q6.
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BS R18675.
BS R18676.
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DR TRANSPATH: MO000056691.
DR EMBL: AF017182; AF017182.
DR UniProtKB: Q04888; SOX10_MOUSE.
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RN [1]; RE0024470.
RX PUBMED: 12668617.
RA Lang D., Epstein J. A.
RT Sox10 and Pax3 physically interact to mediate activation of a conserved c-RET enhancer.
RL Hum. Mol. Genet. 12:937-945 (2003).
RN [2]; RE0035625.
RX PUBMED: 12643284.
RA Slutsky S. G., Kamaraju A. K., Levy A. M., Chebath J., Revel M.
RT Activation of myelin genes during transdifferentiation from melanoma to glial cell phenotype.
RL J. Biol. Chem. 278:8960-8968 (2003).
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