AC T08404
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ID T08404
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DT 17.01.2006 (created); ili.
DT 01.08.2014 (updated); sla.
CO Copyright (C), QIAGEN.
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FA p53-isoform4
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SY Del40-p53; Del40-p53alpha; Delta40p53; DeltaNp53; p47; p53; tp53; TRP53; tumor protein p53 (Li-Fraumeni syndrome).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G001075 TP53; HGNC: tp53.
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CL C0057; P53; 6.3.1.0.1.4.
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SZ 354 AA; 39.3 kDa (calc.), 47 kDa [1]
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SQ MDDLMLSPDDIEQWFTEDPGPDEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPS
SQ QKTYQGSYGFRLGFLHSGTAKSVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRA
SQ MAIYKQSQHMTEVVRRCPHHERCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVP
SQ YEPPEVGSDCTTIHYNYMCNSSCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPG
SQ RDRRTEEENLRKKGEPHHELPPGSTKRALPNNTSSSPQPKKKPLDGEYFTLQIRGRERFE
SQ MFRELNEALELKDAQAGKEPGGSRAHSSHLKSKKGQSTSRHKKLMFKTEGPDSD
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SC UniProt #P04637, edited according to [1]
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FT 56 250 
PF00870; P53 DNA-binding domain.
FT 279 320 
PF07710; P53 tetramerisation motif.
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CP lymphocytes [1].
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FF not able to induce transcription alone [1];
FF does not suppress cell viability but controls p53-mediated suppression of cell viability [1];
FF able to shift the localization of p53 from the nucleus to the cytoplasm [1];
FF potent inhibitor of p53 transcriptional transactivation activity even in the presence of equal or higher levels of p53 [1];
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IN T08404 p53-isoform4; human, Homo sapiens.
IN T00671 p53; human, Homo sapiens.
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MX M00761 V$P53DECAMER_Q2.
MX M00034 V$P53_01.
MX M00272 V$P53_02.
MX M01651 V$P53_03.
MX M01652 V$P53_04.
MX M07054 V$P53_Q3_01.
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DR TRANSPATH: MO000057270.
DR UniProtKB: P04637-4;
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RN [1]; RE0035678.
RX PUBMED: 15340061.
RA Ghosh A., Stewart D., Matlashewski G.
RT Regulation of human p53 activity and cell localization by alternative splicing.
RL Mol. Cell. Biol. 24:7987-7997 (2004).
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