AC T08422
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ID T08422
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DT 18.01.2006 (created); ili.
DT 01.08.2014 (updated); sla.
CO Copyright (C), QIAGEN.
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FA p53-isoform2
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SY I9RET; p53; p53beta; p53i9; tp53; TRP53; tumor protein p53 (Li-Fraumeni syndrome).
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G001075 TP53; HGNC: tp53.
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CL C0057; P53; 6.3.1.0.1.2.
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SZ 341 AA; 37.8 kDa (gene) (calc.), 45-46 kDa (SDS) [1]
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SQ MEEPQSDPSVEPPLSQETFSDLWKLLPENNVLSPLPSQAMDDLMLSPDDIEQWFTEDPGP
SQ DEAPRMPEAAPPVAPAPAAPTPAAPAPAPSWPLSSSVPSQKTYQGSYGFRLGFLHSGTAK
SQ SVTCTYSPALNKMFCQLAKTCPVQLWVDSTPPPGTRVRAMAIYKQSQHMTEVVRRCPHHE
SQ RCSDSDGLAPPQHLIRVEGNLRVEYLDDRNTFRHSVVVPYEPPEVGSDCTTIHYNYMCNS
SQ SCMGGMNRRPILTIITLEDSSGNLLGRNSFEVRVCACPGRDRRTEEENLRKKGEPHHELP
SQ PGSTKRALPNNTSSSPQPKKKPLDGEYFTLQDGTSFQKENC
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SC translated from EMBL #DQ186648
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FT 95 289 
PF00870; P53 DNA-binding domain.
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CP most normal tissues [1].
CN brain, lung, prostate, muscle, fetal brain, spinal cord, and fetal liver [1].
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FF binds differentially to endogenous p53-inducible promoters [1];
FF p53-isoform2 cotransfected with p53 enhances BAX promoter activity but not the p21 promoter activity [1];
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IN T00671 p53; human, Homo sapiens.
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MX M00761 V$P53DECAMER_Q2.
MX M00034 V$P53_01.
MX M00272 V$P53_02.
MX M01651 V$P53_03.
MX M01652 V$P53_04.
MX M07053 V$P53_Q3.
MX M07054 V$P53_Q3_01.
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BS R11272.
BS R16694.
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DR TRANSPATH: MO000057556.
DR EMBL: DQ186648;
DR UniProtKB: P04637-2;
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RN [1]; RE0035675.
RX PUBMED: 16131611.
RA Bourdon J. C., Fernandes K., Murray-Zmijewski F., Liu G., Diot A., Xirodimas D. P., Saville M. K., Lane D. P.
RT p53 isoforms can regulate p53 transcriptional activity.
RL Genes Dev. 19:2122-2137 (2005).
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