AC T08435
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ID T08435
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DT 19.01.2006 (created); ili.
DT 10.08.2006 (updated); man.
CO Copyright (C), QIAGEN.
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FA GCN5-S
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SY hGCN5; YGR252W.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004682 KAT2A; HGNC: KAT2A.
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SZ 427 AA; 48.9 kDa (calc.).
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SQ MGGGSNSSLSLDSAGAEPMPGEKRTLPENLTLEDAKRLRVMGDIPMELVNEVMLTITDPA
SQ AMLGPETSLLSANAARDETARLEERRGIIEFHVIGNSLTPKANRRVLLWLVGLQNVFSHQ
SQ LPRMPKEYIARLVFDPKHKTLALIKDGRVIGGICFRMFPTQGFTEIVFCAVTSNEQVKGY
SQ GTHLMNHLKEYHIKHNILYFLTYADEYAIGYFKKQGFSKDIKVPKSRYLGYIKDYEGATL
SQ MECELNPRIPYTELSHIIKKQKEIIKKLIERKQAQIRKVYPGLSCFKEGVRQIPVESVPG
SQ IRETGWKPLGKEKGKELKDPDQLYTTLKNLLAQIKSHPSAWPFMEPVKKSEAPDYYEVIR
SQ FPIDLKTMTERLRSRYYVTRKLFVADLQRVIANCREYNPPDSEYCRCASALEKFFYFKLK
SQ EGGLIDK
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SC Swiss-Prot#Q92830-2
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FT 141 218 PF00583; Acetyltransferase (GNAT) family.
FT 316 424 SM00297; bromo_6.
FT 323 410 PF00439; Bromodomain.
FT 335 405 PS50014; BROMODOMAIN_2.
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IN T32366 SIRT1-isoform1; mouse, Mus musculus.
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DR TRANSPATH: MO000057743.
DR UniProtKB: Q92830-2;
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RN [1]; RE0047829.
RX PUBMED: 16287840.
RA Faiola F., Liu X., Lo S., Pan S., Zhang K., Lymar E., Farina A., Martinez E.
RT Dual regulation of c-Myc by p300 via acetylation-dependent control of Myc protein turnover and coactivation of Myc-induced transcription.
RL Mol. Cell. Biol. 25:10220-10234 (2005).
RN [2]; RE0048066.
RX PUBMED: 12887892.
RA Fulco M., Schiltz R. L., Iezzi S., King M. T., Zhao P., Kashiwaya Y., Hoffman E., Veech R. L., Sartorelli V.
RT Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.
RL Mol. Cell 12:51-62 (2003).
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