AC T08548
XX
ID T08548
XX
DT 10.02.2006 (created); din.
DT 28.11.2006 (updated); din.
CO Copyright (C), QIAGEN.
XX
FA BRG1-isoform1
XX
SY BAF190; brahma protein-like 1; BRM/SWI2-related gene 1; hSNF2B; SMARCA4; SNF2-beta; SNF2-like 4; SNF2L4; SNF2LB; sucrose nonfermenting-like 4; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G005166 SMARCA4; HGNC: SMARCA4.
XX
SZ 1647 AA; 184.6 kDa (cDNA) (calc.).
XX
SQ MSTPDPPLGGTPRPGPSPGPGPSPGAMLGPSPGPSPGSAHSMMGPSPGPPSAGHPIPTQG
SQ PGGYPQDNMHQMHKPMESMHEKGMSDDPRYNQMKGMGMRSGGHAGMGPPPSPMDQHSQGY
SQ PSPLGGSEHASSPVPASGPSSGPQMSSGPGGAPLDGADPQALGQQNRGPTPFNQNQLHQL
SQ RAQIMAYKMLARGQPLPDHLQMAVQGKRPMPGMQQQMPTLPPPSVSATGPGPGPGPGPGP
SQ GPGPAPPNYSRPHGMGGPNMPPPGPSGVPPGMPGQPPGGPPKPWPEGPMANAAAPTSTPQ
SQ KLIPPQPTGRPSPAPPAVPPAASPVMPPQTQSPGQPAQPAPMVPLHQKQSRITPIQKPRG
SQ LDPVEILQEREYRLQARIAHRIQELENLPGSLAGDLRTKATIELKALRLLNFQRQLRQEV
SQ VVCMRRDTALETALNAKAYKRSKRQSLREARITEKLEKQQKIEQERKRRQKHQEYLNSIL
SQ QHAKDFKEYHRSVTGKIQKLTKAVATYHANTEREQKKENERIEKERMRRLMAEDEEGYRK
SQ LIDQKKDKRLAYLLQQTDEYVANLTELVPQHKAAQVAKEKKKKKKKKKAENAEGQTPAIG
SQ PDGEPLDETSQMSDLPVKVIHVESGKILTGTDAPKAGQLEAWLEMNPGYEVAPRSDSEES
SQ GSEEEEEEEEEEQPQAAQPPTLPVEEKKKIPDPDSDDVSEVDARHIIENAKQDVDDEYGV
SQ SQALARGLQSYYAVAHAVTERVDKQSALMVNGVLKQYQIKGLEWLVSLYNNNLNGILADE
SQ MGLGKTIQTIALITYLMEHKRINGPFLIIVPLSTLSNWAYEFDKWAPSVVKVSYKGSPAA
SQ RRAFVPQLRSGKFNVLLTTYEYIIKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQVLNTH
SQ YVAPRRLLLTGTPLQNKLPELWALLNFLLPTIFKSCSTFEQWFNAPFAMTGEKVDLNEEE
SQ TILIIRRLHKVLRPFLLRRLKKEVEAQLPEKVEYVIKCDMSALQRVLYRHMQAKGVLLTD
SQ GSEKDKKGKGGTKTLMNTIMQLRKICNHPYMFQHIEESFSEHLGFTGGIVQGLDLYRASG
SQ KFELLDRILPKLRATNHKVLLFCQMTSLMTIMEDYFAYRGFKYLRLDGTTKAEDRGMLLK
SQ TFNEPGSEYFIFLLSTRAGGLGLNLQSADTVIIFDSDWNPHQDLQAQDRAHRIGQQNEVR
SQ VLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQKSSSHERRAFLQAILEHEEQDESR
SQ HCSTGSGSASFAHTAPPPAGVNPDLEEPPLKEEDEVPDDETVNQMIARHEEEFDLFMRMD
SQ LDRRREEARNPKRKPRLMEEDELPSWIIKDDAEVERLTCEEEEEKMFGRGSRHRKEVDYS
SQ DSLTEKQWLKAIEEGTLEEIEEEVRQKKSSRKRKRDSDAGSSTPTTSTRSRDKDDESKKQ
SQ KKRGRPPAEKLSPNPPNLTKKMKKIVDAVIKYKDSSSGRQLSEVFIQLPSRKELPEYYEL
SQ IRKPVDFKKIKERIRNHKYRSLNDLEKDVMLLCQNAQTFNLEGSLIYEDSIVLQSVFTSV
SQ RQKIEKEDDSEGEESEEEEEGEEEGSESESRSVKVKIKLGRKEKAQDRLKGGRRRPSRGS
SQ RAKPVVSDDDSEEEQEEDRSGSGSEED
XX
SC translated from EMBL:U29175
XX
FT 408 755 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 460 532 
PF07529; HSA.
FT 460 532 
SM00573; bromneu2.
FT 612 656 
PF07533; Associated with TFs and helicases.
FT 612 656 
SM00592; 122neu5.
FT 750 942 
SM00487; ultradead3.
FT 757 1052 
PF00176; SNF2 family N-terminal domain.
FT 1110 1194 
SM00490; helicmild6.
FT 1115 1194 
PF00271; Helicase conserved C-terminal domain.
FT 1455 1566 
SM00297; bromo_6.
FT 1462 1552 PF00439; Bromodomain.
FT 1477 1547 PS50014; BROMODOMAIN_2.
XX
IN T18770 ARID1B; human, Homo sapiens.
IN T18766 BAF250; human, Homo sapiens.
IN T09128 LAP*-NF-M; chick, Gallus gallus.
XX
DR TRANSPATH: MO000060428.
DR EMBL: D26156;
DR EMBL: U29175;
DR UniProtKB: P51532;
XX
RN [1]; RE0047994.
RX PUBMED: 10619021.
RA Kowenz-Leutz E., Leutz A.
RT A C/EBP beta isoform recruits the SWI/SNF complex to activate myeloid genes.
RL Mol. Cell 4:735-743 (1999).
RN [2]; RE0048534.
RX PUBMED: 16051670.
RA Huang C. Y., Beliakoff J., Li X., Lee J., Li X., Sharma M., Lim B., Sun Z.
RT hZimp7, a novel PIAS-like protein, enhances androgen receptor-mediated transcription and interacts with SWI/SNF-like BAF complexes.
RL Mol. Endocrinol. 19:2915-2929 (2005).
RN [3]; RE0048907.
RX PUBMED: 12200431.
RA Inoue H., Furukawa T., Giannakopoulos S., Zhou S., King D. S., Tanese N.
RT Largest subunits of the human SWI/SNF chromatin-remodeling complex promote transcriptional activation by steroid hormone receptors.
RL J. Biol. Chem. 277:41674-41685 (2002).
XX
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