AC T08676
XX
ID T08676
XX
DT 13.03.2006 (created); sou.
DT 23.09.2013 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA STAT6-isoform1
XX
SY Signal Transducer and Activator of Transcription 1; signal transducer and activator of transcription 6; Stat-6; STAT6A.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G001089 STAT6; HGNC: STAT6.
XX
CL C0039; STAT; 6.2.1.0.7.1.
XX
SZ 847 AA; 94.1 kDa (cDNA) (calc.), 100 kDa (SDS)
XX
SQ MSLWGLVSKMPPEKVQRLYVDFPQHLRHLLGDWLESQPWEFLVGSDAFCCNMASALLSDT
SQ VQHLQASVGEQGEGSTILQHISTLESIYQRDPLKLVATFRQILQGEKKAVIEQFRHLPMP
SQ FHWKQEELKFKTGLRRLQHRVGEIHLLREALQKGAEAGQVSLHSLIETPANGTGPSEALA
SQ MLLQETTGELEAAKALVLKRIQIWKRQQQLAGNGAPFEESLAPLQERCESLVDIYSQLQQ
SQ EVGAAGGELEPKTRASLTGRLDEVLRTLVTSCFLVEKQPPQVLKTQTKFQAGVRFLLGLR
SQ FLGAPAKPPLVRADMVTEKQARELSAPQGPGAGAESTGEIINNTVPLENSIPGNCCSALF
SQ KNLLLKKIKRCERKGTESVTEEKCAVLFSASFTLGPGKLPIQLQALSLPLVVIVHGNQDN
SQ NAKATILWDNAFSEMDRVPFVVAERVPWEKMCETLNLKFMAEVGTNRGLLPEHFLFLAQK
SQ IFNDNSLSMEAFQHRSVSWSQFNKEILLGRGFTFWQWFDGVLDLTKRCLRSYWSDRLIIG
SQ FISKQYVTSLLLNEPDGTFLLRFSDSEIGGITIAHVIRGQDGSPQIENIQPFSAKDLSIR
SQ SLGDRIRDLAQLKNLYPKKPKDEAFRSHYKPEQMGKDGRGYVPATIKMTVERDQPLPTPE
SQ LQMPTMVPSYDLGMAPDSSMSMQLGPDMVPQVYPPHSHSIPPYQGLSPEESVNVLSAFQE
SQ PHLQMPPSLGQMSLPFDQPHPQGLLPCQPQEHAVSSPDPLLCSDVTMVEDSCLSQPVTAF
SQ PQGTWIGEDIFPPLLPPTEQDLTKLLLEGQGESGGGSLGAQPLLQPSHYGQSGISMSHMD
SQ LRANPSW
XX
SC translated from EMBL:U16031
XX
FT 2 116 
PF02865; STAT protein, protein interaction domain.
FT 40 327 
PF00478; IMP dehydrogenase / GMP reductase domain.
FT 124 271 
PF01017; STAT protein, all-alpha domain.
FT 273 527 
PF02864; STAT protein, DNA binding domain.
FT 517 632 
PS50001; SH2.
FT 537 616 
PF00017; SH2 domain.
FT 540 622 
SM00252; SH2_5.
XX
IN T21552 SRC-1; Mammalia.
XX
MX M00494 V$STAT6_01.
MX M00500 V$STAT6_02.
MX M07066 V$STAT6_Q4.
MX M00223 V$STAT_01.
MX M00777 V$STAT_Q6.
XX
BS R11972.
BS R11973.
BS R11974.
BS R11975.
BS R11976.
BS R11977.
BS R11978.
BS R11979.
BS R11980.
BS R11981.
BS R11982.
BS R11983.
BS R11984.
BS R11985.
BS R11986.
BS R11987.
BS R11988.
BS R11989.
BS R11990.
BS R11991.
BS R11992.
BS R11993.
BS R11994.
BS R11995.
BS R11996.
BS R11997.
BS R11998.
BS R11999.
BS R12000.
BS R12001.
BS R12002.
BS R12003.
BS R12004.
BS R12005.
BS R12006.
BS R12007.
BS R12008.
BS R12009.
BS R12010.
BS R12011.
BS R12012.
BS R12013.
BS R12014.
BS R12015.
BS R12016.
BS R20849.
BS R11115.
BS R11183.
BS R11154.
BS R11155.
BS R11184.
BS R13315.
BS R11156.
BS R11157.
BS R04252.
XX
DR TRANSPATH: MO000079060.
DR EMBL: U16031; HS16031.
DR UniProtKB: P42226-1;
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RN [1]; RE0047376.
RX PUBMED: 15793005.
RA Tang X., Marciano D. L., Leeman S. E., Amar S.
RT LPS induces the interaction of a transcription factor, LPS-induced TNF-alpha factor, and STAT6(B) with effects on multiple cytokines.
RL Proc. Natl. Acad. Sci. USA 102:5132-5137 (2005).
RN [2]; RE0052482.
RX PUBMED: 15069079.
RA Wang Y., Malabarba M. G., Nagy Z. S., Kirken R. A.
RT Interleukin 4 regulates phosphorylation of serine 756 in the transactivation domain of Stat6. Roles for multiple phosphorylation sites and Stat6 function.
RL J. Biol. Chem. 279:25196-25203 (2004).
XX
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