AC T21552
XX
ID T21552
XX
DT 10.03.2005 (created); nvo.
DT 08.01.2015 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA SRC-1
XX
SY NCOA1; nuclear receptor coactivator 1; steroid receptor coactivator-1.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T23080 AhR; Mammalia.
IN T30262 alpha-actinin-4-isoform3; human, Homo sapiens.
IN T15601 AR; Mammalia.
IN T10818 arnt; Mammalia.
IN T17532 Bcl-3; Mammalia.
IN T15118 CBP; Mammalia.
IN T08972 EAR2; human, Homo sapiens.
IN T08300 ER-alpha-L; human, Homo sapiens.
IN T00261 ER-alpha; human, Homo sapiens.
IN T16015 ER-beta; Mammalia.
IN T14760 ERR1; Mammalia.
IN T06121 ERR3; human, Homo sapiens.
IN T14067 FOXO1A; Mammalia.
IN T17935 FXR:RXR-alpha; Mammalia.
IN T09632 FXR; human, Homo sapiens.
IN T09300 FXRbeta; mouse, Mus musculus.
IN T01686 GCN5; human, Homo sapiens.
IN T05077 Hey1; mouse, Mus musculus.
IN T23099 Hey1; Mammalia.
IN T10060 HNF-1alpha; Mammalia.
IN T03828 HNF-4alpha; human, Homo sapiens.
IN T08612 HNF-4alpha; Mammalia.
IN T02752 LXR-alpha; human, Homo sapiens.
IN T17874 LXR-alpha; Mammalia.
IN T09029 LXR-beta; human, Homo sapiens.
IN T17658 MR; Mammalia.
IN T05299 NR1B1; human, Homo sapiens.
IN T14193 NR1B1; Mammalia.
IN T01348 Nur77; mouse, Mus musculus.
IN T01427 p300; human, Homo sapiens.
IN T23091 p300; Mammalia.
IN T08431 PPARalpha; mouse, Mus musculus.
IN T09956 PPARalpha; Mammalia.
IN T09957 PPARbeta; Mammalia.
IN T02529 PPARgamma1; mouse, Mus musculus.
IN T03731 PPARgamma2; human, Homo sapiens.
IN T05347 PPARgamma; mouse, Mus musculus.
IN T09963 PPARgamma; Mammalia.
IN T00696 PR B; human, Homo sapiens.
IN T09964 RXR-alpha; Mammalia.
IN T10138 SF-1; Mammalia.
IN T23084 SHP; Mammalia.
IN T14063 SRF; Mammalia.
IN T16819 STAT5A; Mammalia.
IN T08676 STAT6-isoform1; human, Homo sapiens.
IN T09516 STAT6; Mammalia.
IN T08501 T3R-alpha; chick, Gallus gallus.
IN T00851 T3R-beta1; human, Homo sapiens.
IN T04450 T3R-beta2; human, Homo sapiens.
IN T08264 T3R-beta; human, Homo sapiens.
IN T29454 TEF-4; Mammalia.
IN T10505 TTF-1; Mammalia.
IN T08482 VDR-isoform1; human, Homo sapiens.
IN T00882 VDR; rat, Rattus norvegicus.
IN T31896 VDR; Mammalia.
XX
BS R34204.
XX
DR TRANSPATH: MO000046725.
XX
RN [1]; RE0004734.
RX PUBMED: 8616895.
RA Kamei Y., Xu L., Heinzel T., Torchia J., Kurokawa R., Gloss B., Lin S.-C., Heyman R. A., Rose D. W., Glass C. K., Rosenfeld M. G.
RT A CBP integrator complex mediates transcriptional activation and AP-1 inhibition by nuclear receptors
RL Cell 85:403-414 (1996).
RN [2]; RE0013339.
RX PUBMED: 9812974.
RA Wang Jen.-Chywan, Stafford John. M., Granner Daryl. K.
RT SRC-1 and GRIP1 coactivate transcription with hepatocyte nuclear factor 4
RL J. Biol. Chem. 273:30847-30850 (1998).
RN [3]; RE0016194.
RX PUBMED: 10334993.
RA Parks D. J., Blanchard S. G., Bledsoe R. K., Chandra G., Consler T. G., Kliewer S. A., Stimmel J. B., Willson T. M., Zavacki A. M., Moore D. D., Lehmann J. M.
RT Bile acids: natural ligands for an orphan nuclear receptor
RL Science 284:1365-1368 (1999).
RN [4]; RE0018238.
RX PUBMED: 12189208.
RA Surapureddi S., Yu S., Bu H., Hashimoto T., Yeldandi A. V., Kashireddy P., Cherkaoui-Malki M., Qi C., Zhu Y. J., Rao M. S., Reddy J. K.
RT Identification of a transcriptionally active peroxisome proliferator-activated receptor alpha -interacting cofactor complex in rat liver and characterization of PRIC285 as a coactivator.
RL Proc. Natl. Acad. Sci. USA 99:11836-11841 (2002).
RN [5]; RE0022484.
RX PUBMED: 11574547.
RA Litterst C. M., Pfitzner E.
RT Transcriptional activation by STAT6 requires the direct interaction with NCoA-1.
RL J. Biol. Chem. 276:45713-45721 (2001).
RN [6]; RE0022546.
RX PUBMED: 12024042.
RA Beischlag T. V., Wang S., Rose D. W., Torchia J., Reisz-Porszasz S., Muhammad K., Nelson W. E., Probst M. R., Rosenfeld M. G., Hankinson O.
RT Recruitment of the NCoA/SRC-1/p160 family of transcriptional coactivators by the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator complex.
RL Mol. Cell. Biol. 22:4319-4333 (2002).
RN [7]; RE0023349.
RX PUBMED: 10334992.
RA Makishima M., Okamoto A. Y., Repa J. J., Tu H., Learned R. M., Luk A., Hull M. V., Lustig K. D., Mangelsdorf D. J., Shan B.
RT Identification of a nuclear receptor for bile acids.
RL Science 284:1362-1365 (1999).
RN [8]; RE0023352.
RX PUBMED: 12529392.
RA Otte K., Kranz H., Kober I., Thompson P., Hoefer M., Haubold B., Remmel B., Voss H., Kaiser C., Albers M., Cheruvallath Z., Jackson D., Casari G., Koegl M., Paabo S., Mous J., Kremoser C., Deuschle U.
RT Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol.
RL Mol. Cell. Biol. 23:864-872 (2003).
RN [9]; RE0023644.
RX PUBMED: 11076796.
RA Naltner A., Wert S., Whitsett J. A., Yan C.
RT Temporal/spatial expression of nuclear receptor coactivators in the mouse lung.
RL Am. J. Physiol. Lung Cell. Mol. Physiol. 279:L1066-74 (2000).
RN [10]; RE0024943.
RX PUBMED: 12954634.
RA Litterst C. M., Kliem S., Marilley D., Pfitzner E.
RT NCoA-1/SRC-1 is an essential coactivator of STAT5 that binds to the FDL motif in the alpha-helical region of the STAT5 transactivation domain.
RL J. Biol. Chem. 278:45340-45351 (2003).
RN [11]; RE0026591.
RX PUBMED: 10779508.
RA Zhang Z., Teng C. T.
RT Estrogen receptor-related receptor alpha 1 interacts with coactivator and constitutively activates the estrogen response elements of the human lactoferrin gene.
RL J. Biol. Chem. 275:20837-46 (2000).
RN [12]; RE0027648.
RX PUBMED: 10777539.
RA Soutoglou E., Papafotiou G., Katrakili N., Talianidis I.
RT Transcriptional activation by hepatocyte nuclear factor-1 requires synergism between multiple coactivator proteins.
RL J. Biol. Chem. 275:12515-20 (2000).
RN [13]; RE0027754.
RX PUBMED: 10558993.
RA Puigserver P., Adelmant G., Wu Z., Fan M., Xu J., O'Malley B., Spiegelman B. M.
RT Activation of PPARgamma coactivator-1 through transcription factor docking.
RL Science 286:1368-71 (1999).
RN [14]; RE0027787.
RX PUBMED: 10497212.
RA Na S. Y., Choi J. E., Kim H. J., Jhun B. H., Lee Y. C., Lee J. W.
RT Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation.
RL J. Biol. Chem. 274:28491-6 (1999).
RN [15]; RE0028062.
RX PUBMED: 11279171.
RA Elholm M., Dam I., Jorgensen C., Krogsdam A. M., Holst D., Kratchmarova I., Gottlicher M., Gustafsson J. A., Berge R., Flatmark T., Knudsen J., Mandrup S., Kristiansen K.
RT Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors.
RL J. Biol. Chem. 276:21410-6 (2001).
RN [16]; RE0029304.
RX PUBMED: 11606780.
RA Liu Z., Wong J., Tsai S. Y., Tsai M. J., O'Malley B. W.
RT Sequential recruitment of steroid receptor coactivator-1 (SRC-1) and p300 enhances progesterone receptor-dependent initiation and reinitiation of transcription from chromatin.
RL Proc. Natl. Acad. Sci. USA 98:12426-31 (2001).
RN [17]; RE0029309.
RX PUBMED: 11971970.
RA Fu M., Wang C., Wang J., Zhang X., Sakamaki T., Yeung Y. G., Chang C., Hopp T., Fuqua S. A., Jaffray E., Hay R. T., Palvimo J. J., Janne O. A., Pestell R. G.
RT Androgen receptor acetylation governs trans activation and MEKK1-induced apoptosis without affecting in vitro sumoylation and trans-repression function.
RL Mol. Cell. Biol. 22:3373-88 (2002).
RN [18]; RE0029979.
RX PUBMED: 12163482.
RA Ueda T., Mawji N. R., Bruchovsky N., Sadar M. D.
RT Ligand-independent activation of the androgen receptor by interleukin-6 and the role of steroid receptor coactivator-1 in prostate cancer cells.
RL J. Biol. Chem. 277:38087-94 (2002).
RN [19]; RE0030408.
RX PUBMED: 12771131.
RA Agoulnik I. U., Krause W. C., Bingman W. E. 3rd, Rahman H. T., Amrikachi M., Ayala G. E., Weigel N. L.
RT Repressors of androgen and progesterone receptor action.
RL J. Biol. Chem. 278:31136-48 (2003).
RN [20]; RE0030488.
RX PUBMED: 12507421.
RA Picard F., Gehin M., Annicotte J., Rocchi S., Champy M. F., O'Malley B. W., Chambon P., Auwerx J.
RT SRC-1 and TIF2 control energy balance between white and brown adipose tissues.
RL Cell 111:931-41 (2002).
RN [21]; RE0031549.
RX PUBMED: 11477071.
RA Teyssier C., Belguise K., Galtier F., Chalbos D.
RT Characterization of the physical interaction between estrogen receptor alpha and JUN proteins.
RL J. Biol. Chem. 276:36361-9 (2001).
RN [22]; RE0032435.
RX PUBMED: 10380880.
RA Sachsenmaier C., Sadowski H. B., Cooper J. A.
RT STAT activation by the PDGF receptor requires juxtamembrane phosphorylation sites but not Src tyrosine kinase activation.
RL Oncogene 18:3583-92 (1999).
RN [23]; RE0032584.
RX PUBMED: 8663329.
RA Broome M. A., Hunter T.
RT Requirement for c-Src catalytic activity and the SH3 domain in platelet-derived growth factor BB and epidermal growth factor mitogenic signaling.
RL J. Biol. Chem. 271:16798-806 (1996).
RN [24]; RE0032687.
RX PUBMED: 11136553.
RA Bramlett K. S., Yao S., Burris T. P.
RT Correlation of farnesoid X receptor coactivator recruitment and cholesterol 7alpha-hydroxylase gene repression by bile acids.
RL Mol. Genet. Metab. 71:609-15 (2000).
RN [25]; RE0034883.
RX PUBMED: 15367689.
RA Verma S., Ismail A., Gao X., Fu G., Li X., O'Malley B. W., Nawaz Z.
RT The ubiquitin-conjugating enzyme UBCH7 acts as a coactivator for steroid hormone receptors.
RL Mol. Cell. Biol. 24:8716-26 (2004).
RN [26]; RE0035339.
RX PUBMED: 12649293.
RA Rahman M. M., Miyamoto H., Takatera H., Yeh S., Altuwaijri S., Chang C.
RT Reducing the agonist activity of antiandrogens by a dominant-negative androgen receptor coregulator ARA70 in prostate cancer cells.
RL J. Biol. Chem. 278:19619-19626 (2003).
RN [27]; RE0036648.
RX PUBMED: 10947077.
RA Kumar M. B., Perdew G. H.
RT Nuclear receptor coactivator SRC-1 interacts with the Q-rich subdomain of the AhR and modulates its transactivation potential
RL Gene Expr. 8:273-86 (1999).
RN [28]; RE0037663.
RX PUBMED: 10848596.
RA Li M., Pascual G., Glass C. K.
RT Peroxisome proliferator-activated receptor gamma-dependent repression of the inducible nitric oxide synthase gene
RL Mol. Cell. Biol. 20:4699-707 (2000).
RN [29]; RE0037899.
RX PUBMED: 10934189.
RA Belandia B., Parker M. G.
RT Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors
RL J. Biol. Chem. 275:30801-5 (2000).
RN [30]; RE0038010.
RX PUBMED: 10347167.
RA Heinlein C. A., Ting H. J., Yeh S., Chang C.
RT Identification of ARA70 as a ligand-enhanced coactivator for the peroxisome proliferator-activated receptor gamma
RL J. Biol. Chem. 274:16147-52 (1999).
RN [31]; RE0039509.
RX PUBMED: 10999937.
RA Auzou G., Fagart J., Souque A., Hellal-Levy C., Wurtz J. M., Moras D., Rafestin-Oblin M. E.
RT A single amino acid mutation of ala-773 in the mineralocorticoid receptor confers agonist properties to 11beta-substituted spirolactones
RL Mol. Pharmacol. 58:684-91 (2000).
RN [32]; RE0039985.
RX PUBMED: 10082574.
RA Mouchon A., Delmotte M. H., Formstecher P., Lefebvre P.
RT Allosteric regulation of the discriminative responsiveness of retinoic acid receptor to natural and synthetic ligands by retinoid X receptor and DNA
RL Mol. Cell. Biol. 19:3073-85 (1999).
RN [33]; RE0041348.
RX PUBMED: 9786846.
RA Kim H. J., Kim J. H., Lee J. W.
RT Steroid receptor coactivator-1 interacts with serum response factor and coactivates serum response element-mediated transactivations
RL J. Biol. Chem. 273:28564-7 (1998).
RN [34]; RE0042378.
RX PUBMED: 14722092.
RA Matsuda S., Harries J. C., Viskaduraki M., Troke P. J., Kindle K. B., Ryan C., Heery D. M.
RT A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP
RL J. Biol. Chem. 279:14055-64 (2004).
RN [35]; RE0042803.
RX PUBMED: 14985122.
RA Leong G. M., Subramaniam N., Issa L. L., Barry J. B., Kino T., Driggers P. H., Hayman M. J., Eisman J. A., Gardiner E. M.
RT Ski-interacting protein, a bifunctional nuclear receptor coregulator that interacts with N-CoR/SMRT and p300
RL Biochem. Biophys. Res. Commun. 315:1070-6 (2004).
RN [36]; RE0042804.
RX PUBMED: 10454579.
RA Kim H. J., Yi J. Y., Sung H. S., Moore D. D., Jhun B. H., Lee Y. C., Lee J. W.
RT Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation
RL Mol. Cell. Biol. 19:6323-32 (1999).
RN [37]; RE0042892.
RX PUBMED: 11448950.
RA Kim Y. S., Han C. Y., Kim S. W., Kim J. H., Lee S. K., Jung D. J., Park S. Y., Kang H., Choi H. S., Lee J. W., Pak Y. K.
RT The orphan nuclear receptor small heterodimer partner as a novel coregulator of nuclear factor-kappa b in oxidized low density lipoprotein-treated macrophage cell line RAW 264.7
RL J. Biol. Chem. 276:33736-40 (2001).
RN [38]; RE0047189.
RX PUBMED: 15062576.
RA Dotzlaw H., Papaioannou M., Moehren U., Claessens F., Baniahmad A.
RT Agonist-antagonist induced coactivator and corepressor interplay on the human androgen receptor
RL Mol. Cell. Endocrinol. 213:79-85 (2003).
RN [39]; RE0047206.
RX PUBMED: 11447273.
RA Coward P., Lee D., Hull M. V., Lehmann J. M.
RT 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma
RL Proc. Natl. Acad. Sci. USA 98:8880-4 (2001).
RN [40]; RE0047490.
RX PUBMED: 9891040.
RA Takeyama K., Masuhiro Y., Fuse H., Endoh H., Murayama A., Kitanaka S., Suzawa M., Yanagisawa J., Kato S.
RT Selective interaction of vitamin D receptor with transcriptional coactivators by a vitamin D analog.
RL Mol. Cell. Biol. 19:1049-1055 (1999).
RN [41]; RE0047804.
RX PUBMED: 10713182.
RA Zhu X. G., Park K. S., Kaneshige M., Bhat M. K., Zhu Q., Mariash C. N., McPhie P., Cheng S. Y.
RT The orphan nuclear receptor Ear-2 is a negative coregulator for thyroid hormone nuclear receptor function.
RL Mol. Cell. Biol. 20:2604-2618 (2000).
RN [42]; RE0048891.
RX PUBMED: 15923603.
RA Hong C. Y., Suh J. H., Kim K., Gong E. Y., Jeon S. H., Ko M., Seong R. H., Kwon H. B., Lee K.
RT Modulation of androgen receptor transactivation by the SWI3-related gene product (SRG3) in multiple ways.
RL Mol. Cell. Biol. 25:4841-4852 (2005).
RN [43]; RE0049770.
RX PUBMED: 15684393.
RA Belandia B., Powell S. M., Garcia-Pedrero J. M., Walker M. M., Bevan C. L., Parker M. G.
RT Hey1, a mediator of notch signaling, is an androgen receptor corepressor.
RL Mol. Cell. Biol. 25:1425-1436 (2005).
RN [44]; RE0050145.
RX PUBMED: 12963727.
RA Shaw N., Elholm M., Noy N.
RT Retinoic acid is a high affinity selective ligand for the peroxisome proliferator-activated receptor beta/delta.
RL J. Biol. Chem. 278:41589-41592 (2003).
RN [45]; RE0050363.
RX PUBMED: 16202384.
RA Goto T., Takahashi N., Kato S., Egawa K., Ebisu S., Moriyama T., Fushiki T., Kawada T.
RT Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes.
RL Biochem. Biophys. Res. Commun. 337:440-445 (2005).
RN [46]; RE0050364.
RX PUBMED: 12573447.
RA Soderstrom M., Wigren J., Surapureddi S., Glass C. K., Hammarstrom S.
RT Novel prostaglandin D(2)-derived activators of peroxisome proliferator-activated receptor-gamma are formed in macrophage cell cultures.
RL Biochim. Biophys. Acta 1631:35-41 (2003).
RN [47]; RE0050413.
RX PUBMED: 12740008.
RA Wigren J., Surapureddi S., Olsson A. G., Glass C. K., Hammarstrom S., Soderstrom M.
RT Differential recruitment of the coactivator proteins CREB-binding protein and steroid receptor coactivator-1 to peroxisome proliferator-activated receptor gamma/9-cis-retinoic acid receptor heterodimers by ligands present in oxidized low-density lipoprotein.
RL J. Endocrinol. 177:207-214 (2003).
RN [48]; RE0050415.
RX PUBMED: 17095203.
RA Awais M., Sato M., Umezawa Y.
RT A fluorescent indicator to visualize ligand-induced receptor/coactivator interactions for screening of peroxisome proliferator-activated receptor gamma ligands in living cells.
RL Biosens. Bioelectron. 22:2564-2569 (2007).
RN [49]; RE0050526.
RX PUBMED: 11027271.
RA Yang W., Rachez C., Freedman L. P.
RT Discrete roles for peroxisome proliferator-activated receptor gamma and retinoid X receptor in recruiting nuclear receptor coactivators.
RL Mol. Cell. Biol. 20:8008-8017 (2000).
RN [50]; RE0050565.
RX PUBMED: 17259669.
RA Tien E. S., Hannon D. B., Thompson J. T., Vanden Heuvel J. P.
RT Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha).
RL PPAR Res. 2006:69612 (2006).
RN [51]; RE0050991.
RX PUBMED: 16675527.
RA Wang S., Lai K., Moy F. J., Bhat A., Hartman H. B., Evans M. J.
RT The nuclear hormone receptor farnesoid X receptor (FXR) is activated by androsterone.
RL Endocrinology 147:4025-4033 (2006).
RN [52]; RE0050998.
RX PUBMED: 11504730.
RA Fu X., Menke J. G., Chen Y., Zhou G., MacNaul K. L., Wright S. D., Sparrow C. P., Lund E. G.
RT 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.
RL J. Biol. Chem. 276:38378-38387 (2001).
RN [53]; RE0051051.
RX PUBMED: 15187081.
RA Pineda Torra I., Freedman L. P., Garabedian M. J.
RT Identification of DRIP205 as a coactivator for the Farnesoid X receptor.
RL J. Biol. Chem. 279:36184-36191 (2004).
RN [54]; RE0051058.
RX PUBMED: 16415294.
RA Schmidt R. J., Ficorilli J. V., Zhang Y., Bramlett K. S., Beyer T. P., Borchert K., Dowless M. S., Houck K. A., Burris T. P., Eacho P. I., Liang G., Guo L. W., Wilson W. K., Michael L. F., Cao G.
RT A 15-ketosterol is a liver X receptor ligand that suppresses sterol-responsive element binding protein-2 activity.
RL J. Lipid Res. 47:1037-1044 (2006).
RN [55]; RE0051114.
RX PUBMED: 12016314.
RA Makishima M., Lu T. T., Xie W., Whitfield G. K., Domoto H., Evans R. M., Haussler M. R., Mangelsdorf D. J.
RT Vitamin D receptor as an intestinal bile acid sensor.
RL Science 296:1313-1316 (2002).
RN [56]; RE0051257.
RX PUBMED: 15307955.
RA Zhao A., Yu J., Lew J. L., Huang L., Wright S. D., Cui J.
RT Polyunsaturated fatty acids are FXR ligands and differentially regulate expression of FXR targets.
RL DNA Cell Biol. 23:519-526 (2004).
RN [57]; RE0051265.
RX PUBMED: 17296605.
RA Yamamoto T., Shimano H., Inoue N., Nakagawa Y., Matsuzaka T., Takahashi A., Yahagi N., Sone H., Suzuki H., Toyoshima H., Yamada N.
RT Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver.
RL J. Biol. Chem. 282:11687-11695 (2007).
RN [58]; RE0051267.
RX PUBMED: 16300737.
RA Nishimaki-Mogami T., Kawahara Y., Tamehiro N., Yoshida T., Inoue K., Ohno Y., Nagao T., Une M.
RT 5Alpha-bile alcohols function as farnesoid X receptor antagonists.
RL Biochem. Biophys. Res. Commun. 339:386-391 (2006).
RN [59]; RE0051278.
RX PUBMED: 12525500.
RA Cui J., Huang L., Zhao A., Lew J. L., Yu J., Sahoo S., Meinke P. T., Royo I., Pelaez F., Wright S. D.
RT Guggulsterone is a farnesoid X receptor antagonist in coactivator association assays but acts to enhance transcription of bile salt export pump.
RL J. Biol. Chem. 278:10214-10220 (2003).
RN [60]; RE0051310.
RX PUBMED: 16354658.
RA Albers M., Blume B., Schlueter T., Wright M. B., Kober I., Kremoser C., Deuschle U., Koegl M.
RT A novel principle for partial agonism of liver X receptor ligands. Competitive recruitment of activators and repressors.
RL J. Biol. Chem. 281:4920-4930 (2006).
RN [61]; RE0051387.
RX PUBMED: 12052824.
RA Yu J., Lo J. L., Huang L., Zhao A., Metzger E., Adams A., Meinke P. T., Wright S. D., Cui J.
RT Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity.
RL J. Biol. Chem. 277:31441-31447 (2002).
RN [62]; RE0051608.
RX PUBMED: 11641412.
RA Gan X., Kaplan R., Menke J. G., MacNaul K., Chen Y., Sparrow C. P., Zhou G., Wright S. D., Cai T. Q.
RT Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate.
RL J. Biol. Chem. 276:48702-48708 (2001).
RN [63]; RE0051657.
RX PUBMED: 17456796.
RA Ricketts M. L., Boekschoten M. V., Kreeft A. J., Hooiveld G. J., Moen C. J., Muller M., Frants R. R., Kasanmoentalib S., Post S. M., Princen H. M., Porter J. G., Katan M. B., Hofker M. H., Moore D. D.
RT The cholesterol-raising factor from coffee beans, cafestol, as an agonist ligand for the farnesoid and pregnane X receptors.
RL Mol. Endocrinol. 21:1603-1616 (2007).
RN [64]; RE0052791.
RX PUBMED: 17449871.
RA Deng X., Yellaturu C., Cagen L., Wilcox H. G., Park E. A., Raghow R., Elam M. B.
RT Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).
RL J. Biol. Chem. 282:17517-17529 (2007).
RN [65]; RE0053156.
RX PUBMED: 12220494.
RA Wisely G. B., Miller A. B., Davis R. G., Thornquest AD J. r., Johnson R., Spitzer T., Sefler A., Shearer B., Moore J. T., Miller A. B., Willson T. M., Williams S. P.
RT Hepatocyte nuclear factor 4 is a transcription factor that constitutively binds fatty acids.
RL Structure 10:1225-1234 (2002).
RN [66]; RE0053494.
RX PUBMED: 12138194.
RA Lee H., Bai W.
RT Regulation of estrogen receptor nuclear export by ligand-induced and p38-mediated receptor phosphorylation.
RL Mol. Cell. Biol. 22:5835-5845 (2002).
RN [67]; RE0053683.
RX PUBMED: 16753019.
RA Nguyen M., d'Alesio A., Pascussi J. M., Kumar R., Griffin M. D., Dong X., Guillozo H., Rizk-Rabin M., Sinding C., Bougneres P., Jehan F., Garabedian M.
RT Vitamin D-resistant rickets and type 1 diabetes in a child with compound heterozygous mutations of the vitamin D receptor (L263R and R391S): dissociated responses of the CYP-24 and rel-B promoters to 1,25-dihydroxyvitamin D3.
RL J. Bone Miner. Res. 21:886-894 (2006).
RN [68]; RE0063653.
RX PUBMED: 16497732.
RA Miao F., Li S., Chavez V., Lanting L., Natarajan R.
RT Coactivator-associated arginine methyltransferase-1 enhances nuclear factor-kappaB-mediated gene transcription through methylation of histone H3 at arginine 17.
RL Mol. Endocrinol. 20:1562-1573 (2006).
RN [69]; RE0067497.
RX PUBMED: 15530426.
RA Zhao H., Nakajima R., Kunimoto H., Sasaki T., Kojima H., Nakajima K.
RT Region 752-761 of STAT3 is critical for SRC-1 recruitment and Ser727 phosphorylation.
RL Biochem. Biophys. Res. Commun. 325:541-548 (2004).
RN [70]; RE0068910.
RX PUBMED: 19487700.
RA Privalsky M. L., Lee S., Hahm J. B., Young B. M., Fong R. N., Chan I. H.
RT The p160 coactivator PAS-B motif stabilizes nuclear receptor binding and contributes to isoform-specific regulation by thyroid hormone receptors.
RL J. Biol. Chem. 284:19554-19563 (2009).
XX
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