AC T09964
XX
ID T09964
XX
DT 10.03.2005 (created); nvo.
DT 16.06.2016 (updated); sup.
CO Copyright (C), QIAGEN.
XX
FA RXR-alpha
XX
SY RXRA.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T05777 ASC-2-isoform1; mouse, Mus musculus.
IN T14513 beta-catenin; Mammalia.
IN T23079 CAR; Mammalia.
IN T10260 CLOCK; human, Homo sapiens.
IN T18364 Clock; Mammalia.
IN T10201 COUP-TF1; Mammalia.
IN T25698 DRIP205-isoform4; mouse, Mus musculus.
IN T17105 FXR; Mammalia.
IN T02752 LXR-alpha; human, Homo sapiens.
IN T09029 LXR-beta; human, Homo sapiens.
IN T08888 LXRalpha-isoform1; human, Homo sapiens.
IN T11196 MOP4; human, Homo sapiens.
IN T18783 MRF1; human, Homo sapiens.
IN T08641 NCOR1-isoform1; mouse, Mus musculus.
IN T04688 NCOR1; mouse, Mus musculus.
IN T14193 NR1B1; Mammalia.
IN T10625 Nur77; Mammalia.
IN T23091 p300; Mammalia.
IN T09956 PPARalpha; Mammalia.
IN T09957 PPARbeta; Mammalia.
IN T09963 PPARgamma; Mammalia.
IN T23084 SHP; Mammalia.
IN T04632 SRC-1; human, Homo sapiens.
IN T21552 SRC-1; Mammalia.
IN T23076 STAT1; Mammalia.
IN T15588 T3R-beta1; Mammalia.
IN T16578 TGIF; Mammalia.
IN T08482 VDR-isoform1; human, Homo sapiens.
IN T31896 VDR; Mammalia.
XX
MX M00966 V$DR3_Q4.
MX M00965 V$DR4_Q2.
MX M07280 V$NR1NR2_Q3.
MX M00518 V$PPARA_02.
MX M00963 V$T3R_Q6.
XX
BS R23650.
BS R31343.
BS R10085.
BS R03017.
BS R15845.
BS R27533.
BS R35224.
BS R35225.
BS R27274.
BS R27360.
BS R27358.
XX
DR TRANSPATH: MO000047140.
XX
RN [1]; RE0016043.
RX PUBMED: 8621574.
RA Miyata K. S., McCaw S. E., Patel H. V., Rachubinski R. A., Capone J. P.
RT The orphan nuclear hormone receptor LXR alpha interacts with the peroxisome proliferator-activated receptor and inhibits peroxisome proliferator signaling
RL J. Biol. Chem. 271:9189-9192 (1996).
RN [2]; RE0016813.
RX PUBMED: 10336495.
RA Dowell P., Ishmael J. E., Avram D., Peterson V. J., Nevrivy D. J., Leid M.
RT Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein
RL J. Biol. Chem. 274:15901-15907 (1999).
RN [3]; RE0022684.
RX PUBMED: 10938283.
RA Lee H.-Y., Suh Y.-A., Robinson M. J., Clifford J. L., Hong W. K., Woodgett J. R., Cobb M. H., Mangelsdorf D. J., Kurie J. M.
RT Stress pathway activation induces phosphorylation of retinoid X receptor.
RL J. Biol. Chem. 275:32193-32199 (2000).
RN [4]; RE0024454.
RX PUBMED: 12771132.
RA Xiao J. H., Ghosn C., Hinchman C., Forbes C., Wang J., Snider N., Cordrey A., Zhao Y., Chandraratna R. A.
RT Adenomatous polyposis coli (APC)-independent regulation of beta-catenin degradation via a retinoid X receptor-mediated pathway.
RL J. Biol. Chem. 278:29954-29962 (2003).
RN [5]; RE0024500.
RX PUBMED: 12015306.
RA Helledie T., Grontved L., Jensen S. S., Kiilerich P., Rietveld L., Albrektsen T., Boysen M. S., Nohr J., Larsen L. K., Fleckner J., Stunnenberg H. G., Kristiansen K., Mandrup S.
RT The gene encoding the Acyl-CoA-binding protein is activated by peroxisome proliferator-activated receptor gamma through an intronic response element functionally conserved between humans and rodents.
RL J. Biol. Chem. 277:26821-26830 (2002).
RN [6]; RE0025773.
RX PUBMED: 12048211.
RA Dwivedi P. P., Hii C. S., Ferrante A., Tan J., Der C. J., Omdahl J. L., Morris H. A., May B. K.
RT Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5.
RL J. Biol. Chem. 277:29643-53 (2002).
RN [7]; RE0026435.
RX PUBMED: 10788465.
RA Zhu Y., Kan L., Qi C., Kanwar Y. S., Yeldandi A. V., Rao M. S., Reddy J. K.
RT Isolation and characterization of peroxisome proliferator-activated receptor (PPAR) interacting protein (PRIP) as a coactivator for PPAR.
RL J. Biol. Chem. 275:13510-6 (2000).
RN [8]; RE0027683.
RX PUBMED: 10517671.
RA Monden T., Kishi M., Hosoya T., Satoh T., Wondisford F. E., Hollenberg A. N., Yamada M., Mori M.
RT p120 acts as a specific coactivator for 9-cis-retinoic acid receptor (RXR) on peroxisome proliferator-activated receptor-gamma/RXR heterodimers.
RL Mol. Endocrinol. 13:1695-703 (1999).
RN [9]; RE0031471.
RX PUBMED: 14993281.
RA Wang J., Yen A.
RT A novel retinoic acid-responsive element regulates retinoic acid-induced BLR1 expression.
RL Mol. Cell. Biol. 24:2423-43 (2004).
RN [10]; RE0031763.
RX PUBMED: 12235159.
RA Zeng M., Kumar A., Meng G., Gao Q., Dimri G., Wazer D., Band H., Band V.
RT Human papilloma virus 16 E6 oncoprotein inhibits retinoic X receptor-mediated transactivation by targeting human ADA3 coactivator.
RL J. Biol. Chem. 277:45611-8 (2002).
RN [11]; RE0036288.
RX PUBMED: 14981089.
RA Takano Y., Adachi S., Okuno M., Muto Y., Yoshioka T., Matsushima-Nishiwaki R., Tsurumi H., Ito K., Friedman S. L., Moriwaki H., Kojima S., Okano Y.
RT The RING finger protein, RNF8, interacts with retinoid X receptor alpha and enhances its transcription-stimulating activity
RL J. Biol. Chem. 279:18926-34 (2004).
RN [12]; RE0036899.
RX PUBMED: 10976925.
RA Loudig O., Babichuk C., White J., Abu-Abed S., Mueller C., Petkovich M.
RT Cytochrome P450RAI(CYP26) promoter: a distinct composite retinoic acid response element underlies the complex regulation of retinoic acid metabolism
RL Mol. Endocrinol. 14:1483-97 (2000).
RN [13]; RE0036903.
RX PUBMED: 9442090.
RA Abu-Abed S. S., Beckett B. R., Chiba H., Chithalen J. V., Jones G., Metzger D., Chambon P., Petkovich M.
RT Mouse P450RAI (CYP26) expression and retinoic acid-inducible retinoic acid metabolism in F9 cells are regulated by retinoic acid receptor gamma and retinoid X receptor alpha
RL J. Biol. Chem. 273:2409-15 (1998).
RN [14]; RE0037207.
RX PUBMED: 12480945.
RA Clabby M. L., Robison T. A., Quigley H. F., Wilson D. B., Kelly D. P.
RT Retinoid X receptor alpha represses GATA-4-mediated transcription via a retinoid-dependent interaction with the cardiac-enriched repressor FOG-2
RL J. Biol. Chem. 278:5760-7 (2003).
RN [15]; RE0037650.
RX PUBMED: 12039952.
RA Qi C., Chang J., Zhu Y., Yeldandi A. V., Rao S. M., Zhu Y. J.
RT Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha
RL J. Biol. Chem. 277:28624-30 (2002).
RN [16]; RE0039064.
RX PUBMED: 10022764.
RA Miyata K. S., McCaw S. E., Meertens L. M., Patel H. V., Rachubinski R. A., Capone J. P.
RT Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor alpha and liver-X-receptor alpha
RL Mol. Cell. Endocrinol. 146:69-76 (1998).
RN [17]; RE0039828.
RX PUBMED: 10772826.
RA Kang H. J., Song M. R., Lee S. K., Shin E. C., Choi Y. H., Kim S. J., Lee J. W., Lee M. O.
RT Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: a possible mechanism for the inhibition of apoptosis by retinoic acid
RL Exp. Cell Res. 256:545-54 (2000).
RN [18]; RE0039923.
RX PUBMED: 10640450.
RA Ohata M., Yamauchi M., Takeda K., Toda G., Kamimura S., Motomura K., Xiong S., Tsukamoto H.
RT RAR and RXR expression by Kupffer cells
RL Exp. Mol. Pathol. 68:13-20 (2000).
RN [19]; RE0040618.
RX PUBMED: 9325263.
RA Zhu Y., Qi C., Jain S., Rao M. S., Reddy J. K.
RT Isolation and characterization of PBP, a protein that interacts with peroxisome proliferator-activated receptor
RL J. Biol. Chem. 272:25500-6 (1997).
RN [20]; RE0040916.
RX PUBMED: 11594759.
RA Hirotani M., Tsukamoto T., Bourdeaux J., Sadano H., Osumi T.
RT Stabilization of peroxisome proliferator-activated receptor alpha by the ligand
RL Biochem. Biophys. Res. Commun. 288:106-10 (2001).
RN [21]; RE0042695.
RX PUBMED: 11386849.
RA Malloy P. J., Zhu W., Zhao X. Y., Pehling G. B., Feldman D.
RT A novel inborn error in the ligand-binding domain of the vitamin D receptor causes hereditary vitamin D-resistant rickets
RL Mol. Genet. Metab. 73:138-48 (2001).
RN [22]; RE0042891.
RX PUBMED: 12198243.
RA Brendel C., Schoonjans K., Botrugno O. A., Treuter E., Auwerx J.
RT The Small Heterodimer Partner Interacts with the Liver X Receptor alpha and Represses Its Transcriptional Activity
RL Mol. Endocrinol. 16:2065-76 (2002).
RN [23]; RE0043536.
RX PUBMED: 11278173.
RA Mochizuki K., Suruga K., Yagi E., Takase S., Goda T.
RT The expression of PPAR-associated genes is modulated through postnatal development of PPAR subtypes in the small intestine
RL Biochim. Biophys. Acta 1531:68-76 (2001).
RN [24]; RE0043640.
RX PUBMED: 10936484.
RA Kintscher U., Goetze S., Wakino S., Kim S., Nagpal S., Chandraratna R. A., Graf K., Fleck E., Hsueh W. A., Law R. E.
RT Peroxisome proliferator-activated receptor and retinoid X receptor ligands inhibit monocyte chemotactic protein-1-directed migration of monocytes
RL Eur. J. Pharmacol. 401:259-70 (2000).
RN [25]; RE0043974.
RX PUBMED: 11283155.
RA Desreumaux P., Dubuquoy L., Nutten S., Peuchmaur M., Englaro W., Schoonjans K., Derijard B., Desvergne B., Wahli W., Chambon P., Leibowitz M. D., Colombel J. F., Auwerx J.
RT Attenuation of colon inflammation through activators of the retinoid X receptor (RXR)/peroxisome proliferator-activated receptor gamma (PPARgamma) heterodimer. A basis for new therapeutic strategies
RL J. Exp. Med. 193:827-38 (2001).
RN [26]; RE0045093.
RX PUBMED: 15191360.
RA Gong H., Ni Y., Guo X., Fei L., Pan X., Guo M., Chen R.
RT Resistin promotes 3T3-L1 preadipocyte differentiation
RL Eur. J. Endocrinol. 150:885-92 (2004).
RN [27]; RE0047433.
RX PUBMED: 9878542.
RA Tagami T., Lutz W. H., Kumar R., Jameson J. L.
RT The interaction of the vitamin D receptor with nuclear receptor corepressors and coactivators.
RL Biochem. Biophys. Res. Commun. 253:358-363 (1998).
RN [28]; RE0047662.
RX PUBMED: 10874028.
RA Liu B., Lee H. Y., Weinzimer S. A., Powell D. R., Clifford J. L., Kurie J. M., Cohen P.
RT Direct functional interactions between insulin-like growth factor-binding protein-3 and retinoid X receptor-alpha regulate transcriptional signaling and apoptosis.
RL J. Biol. Chem. 275:33607-33613 (2000).
RN [29]; RE0047682.
RX PUBMED: 12040021.
RA Brendel C., Gelman L., Auwerx J.
RT Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism.
RL Mol. Endocrinol. 16:1367-1377 (2002).
RN [30]; RE0049512.
RX PUBMED: 16428452.
RA Bartholin L., Powers S. E., Melhuish T. A., Lasse S., Weinstein M., Wotton D.
RT TGIF inhibits retinoid signaling.
RL Mol. Cell. Biol. 26:990-1001 (2006).
RN [31]; RE0049975.
RX PUBMED: 11060349.
RA Zomer A. W., van der Burg B., Jansen G. A., Wanders R. J., Poll-The B. T., van der Saag P. T.
RT Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor alpha.
RL J. Lipid Res. 41:1801-1807 (2000).
RN [32]; RE0050526.
RX PUBMED: 11027271.
RA Yang W., Rachez C., Freedman L. P.
RT Discrete roles for peroxisome proliferator-activated receptor gamma and retinoid X receptor in recruiting nuclear receptor coactivators.
RL Mol. Cell. Biol. 20:8008-8017 (2000).
RN [33]; RE0050548.
RX PUBMED: 16554032.
RA Surapureddi S., Viswakarma N., Yu S., Guo D., Rao MS., Reddy JK.
RT PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.
RL Biochem. Biophys. Res. Commun. 343:535-43 (2006).
RN [34]; RE0050569.
RX PUBMED: 17595322.
RA Li D., Kang Q., Wang D. M.
RT CCPG, a Novel Constitutive Coactivator of PPAR{gamma} that Promotes Adipogenesis.
RL Mol. Endocrinol. 21:2320-2333 (2007).
RN [35]; RE0051799.
RX PUBMED: 9280066.
RA Masuyama H., Brownfield C. M., St-Arnaud R., MacDonald P. N.
RT Evidence for ligand-dependent intramolecular folding of the AF-2 domain in vitamin D receptor-activated transcription and coactivator interaction.
RL Mol. Endocrinol. 11:1507-1517 (1997).
RN [36]; RE0052028.
RX PUBMED: 10318858.
RA Kraichely D. M., Collins JJ 3. r. d., DeLisle R. K., MacDonald P. N.
RT The autonomous transactivation domain in helix H3 of the vitamin D receptor is required for transactivation and coactivator interaction.
RL J. Biol. Chem. 274:14352-14358 (1999).
RN [37]; RE0058934.
RX PUBMED: 11855864.
RA Boudjelal M., Voorhees J. J., Fisher G. J.
RT Retinoid signaling is attenuated by proteasome-mediated degradation of retinoid receptors in human keratinocyte HaCaT cells.
RL Exp. Cell Res. 274:130-137 (2002).
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