AC T10260
XX
ID T10260
XX
DT 20.02.2007 (created); sri.
DT 30.04.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA CLOCK
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SY circadian locomoter output cycles kaput protein; hCLOCK.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005941 CLOCK; HGNC: CLOCK.
XX
CL C0010; bHLH.
XX
SZ 846 AA; 95.3 kDa (calc.).
XX
SQ MLFTVSCSKMSSIVDRDDSSIFDGLVEEDDKDKAKRVSRNKSEKKRRDQFNVLIKELGSM
SQ LPGNARKMDKSTVLQKSIDFLRKHKEITAQSDASEIRQDWKPTFLSNEEFTQLMLEALDG
SQ FFLAIMTDGSIIYVSESVTSLLEHLPSDLVDQSIFNFIPEGEHSEVYKILSTHLLESDSL
SQ TPEYLKSKNQLEFCCHMLRGTIDPKEPSTYEYVKFIGNFKSLNSVSSSAHNGFEGTIQRT
SQ HRPSYEDRVCFVATVRLATPQFIKEMCTVEEPNEEFTSRHSLEWKFLFLDHRAPPIIGYL
SQ PFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTHYYITYH
SQ QWNSRPEFIVCTHTVVSYAEVRAERRRELGIEESLPETAADKSQDSGSDNRINTVSLKEA
SQ LERFDHSPTPSASSRSSRKSSHTAVSDPSSTPTKIPTDTSTPPRQHLPAHEKMVQRRSSF
SQ SSQSINSQSVGSSLTQPVMSQATNLPIPQGMSQFQFSAQLGAMQHLKDQLEQRTRMIEAN
SQ IHRQQEELRKIQEQLQMVHGQGLQMFLQQSNPGLNFGSVQLSSGNSSNIQQLAPINMQGQ
SQ VVPTNQIQSGMNTGHIGTTQHMIQQQTLQSTSTQSQQNVLSGHSQQTSLPSQTQSTLTAP
SQ LYNTMVISQPAAGSMVQIPSSMPQNSTQSAAVTTFTQDRQIRFSQGQQLVTKLVTAPVAC
SQ GAVMVPSTMLMGQVVTAYPTFATQQQQSQTLSVTQQQQQQSSQEQQLTSVQQPSQAQLTQ
SQ PPQQFLQTSRLLHGNPSTQLILSAAFPLQQSTFPQSHHQQHQSQQQQQLSRHRTDSLPDP
SQ SKVQPQ
XX
SC translated from EMBL #AF011568
XX
FT 33 85 
PS50888; HLH.
FT 35 85 
PF00010; Helix-loop-helix DNA-binding domain.
FT 40 90 
SM00353; finulus.
FT 107 177 
PS50112; PAS.
FT 109 175 
SM00091; pas_2.
FT 264 330 
SM00091; pas_2.
FT 285 332 
PS50112; PAS.
FT 336 379 
SM00086; pac_2.
FT 355 764 
PF00478; IMP dehydrogenase / GMP reductase domain.
XX
IN T02720 BMAL1; human, Homo sapiens.
IN T23329 BMAL1; Mammalia.
IN T09187 Id2; human, Homo sapiens.
IN T01809 Id3; human, Homo sapiens.
IN T05299 NR1B1; human, Homo sapiens.
IN T14193 NR1B1; Mammalia.
IN T08433 RXR-alpha; human, Homo sapiens.
IN T09964 RXR-alpha; Mammalia.
XX
MX M08868 V$ARNTLIKE_Q6.
MX M07247 V$CLOCK_Q6.
XX
DR TRANSPATH: MO000099511.
DR EMBL: AB002332;
DR EMBL: AB005535;
DR EMBL: AF011568;
DR EMBL: AF097442;
DR EMBL: AF097443;
DR EMBL: AF097444;
DR EMBL: AF097445;
DR EMBL: AF097446;
DR EMBL: AF097447;
DR EMBL: AF097448;
DR EMBL: AF097449;
DR EMBL: AF097450;
DR EMBL: AF097451;
DR EMBL: AF097452;
DR EMBL: AF097453;
DR EMBL: AF097454;
DR EMBL: AF097455;
DR EMBL: AF097456;
DR EMBL: AF097457;
DR EMBL: AF097458;
DR UniProtKB: O15516;
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RN [1]; RE0017170.
RX PUBMED: 10198158.
RA Steeves T. D., King D. P., Zhao Y., Sangoram A. M., Du F., Bowcock A. M., Moore R. Y., Takahashi J. S.
RT Molecular cloning and characterization of the human CLOCK gene: expression in the suprachiasmatic nuclei
RL Genomics 57:189-200 (1999).
XX
//