AC T09187
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ID T09187
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DT 07.08.2006 (created); man.
DT 29.12.2014 (updated); ros.
CO Copyright (C), QIAGEN.
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FA Id2
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SY Id-2; inhibitor of DNA-binding 2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003949 ID2; HGNC: ID2.
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CL C0011; HLH.
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SZ 134 AA; 14.9 kDa (cDNA) (calc.).
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SQ MKAFSPVRSVRKNSLSDHSLGISRSKTPVDDPMSLLYNMNDCYSKLKELVPSIPQNKKVS
SQ KMEILQHVIDYILDLQIALDSHPTIVSLHHQRPGQNQASRTPLTTLNTDISILSLQASEF
SQ PSELMSNDSKALCG
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SC Swiss-Prot#Q02363
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FT 8 76 
PS50888; HLH.
FT 24 76 
PF00010; Helix-loop-helix DNA-binding domain.
FT 28 81 
SM00353; finulus.
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IN T05869 BMAL1; mouse, Mus musculus.
IN T05868 Clock; mouse, Mus musculus.
IN T10260 CLOCK; human, Homo sapiens.
IN T00525 MyoD; human, Homo sapiens.
IN T16059 pax-2; mouse, Mus musculus.
IN T09204 Pax-5-isoform1; human, Homo sapiens.
IN T09184 Pax-8; mouse, Mus musculus.
IN T16654 SAP-1; Mammalia.
IN T15307 SNA; mouse, Mus musculus.
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DR TRANSPATH: MO000084433.
DR EMBL: D13891;
DR EMBL: L31815;
DR EMBL: M97796;
DR UniProtKB: Q02363;
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RN [1]; RE0002425.
RX PUBMED: 1741406.
RA Biggs J., Murphy E. V., Israel M. A.
RT A human Id-like helix-loop-helix protein expressed during early development
RL Proc. Natl. Acad. Sci. USA 89:1512-1516 (1992).
RN [2]; RE0004172.
RX PUBMED: 7983058.
RA Kurabayashi M., Dutta S., Kedes L.
RT Serum-inducible factors binding to an activating transcription factor motif regulate transcription of the Id2A promoter during myogenic differentiation
RL J. Biol. Chem. 269:31162-31170 (1994).
RN [3]; RE0004173.
RX PUBMED: 7926730.
RA Iavarone A., Garg P., Lasorella A., Hsu J., Israel M. A.
RT The helix-loop-helix protein Id-2 enhances cell proliferation and binds to the retinoblastoma protein
RL Genes Dev. 8:1270-1284 (1994).
RN [4]; RE0004174.
RX PUBMED: 8224921.
RA Kurabayashi M., Jeyaseelan R., Kedes L.
RT Two distinct cDNA sequences encoding the human helix-loop-helix protein Id2
RL Gene 133:305-306 (1993).
RN [5]; RE0005842.
RX PUBMED: 8294468.
RA Hara E., Yamaguchi T., Nojima H., Ide T., Campisi J., Okayama H., Oda K.
RT Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts
RL J. Biol. Chem. 269:2139-2145 (1994).
RN [6]; RE0039511.
RX PUBMED: 9235903.
RA Anand G., Yin X., Shahidi A. K., Grove L., Prochownik E. V.
RT Novel regulation of the helix-loop-helix protein Id1 by S5a, a subunit of the 26 S proteasome
RL J. Biol. Chem. 272:19140-51 (1997).
RN [7]; RE0049099.
RX PUBMED: 10502414.
RA Law S. F., Zhang Y. Z., Fashena S. J., Toby G., Estojak J., Golemis E. A.
RT Dimerization of the docking/adaptor protein HEF1 via a carboxy-terminal helix-loop-helix domain.
RL Exp. Cell Res. 252:224-235 (1999).
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