TRANSFAC-Logo

TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T09184 XX ID T09184 XX DT 02.08.2006 (created); jul. DT 26.06.2012 (updated); hna. CO Copyright (C), QIAGEN. XX FA Pax-8 XX SY mPax-8; mPax8; PAX8. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G006535 Pax8. XX CL C0017; paired. XX SZ 457 AA; 48.8 kDa (cDNA) (calc.). XX SQ MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK SQ ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND SQ TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY SQ SINGLLGIAQPGNDNKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDTFSQHHLEALECP SQ FERQHYPEAYASPSHTKGEQGLYPLPLLNSALDDGKATLTSSNTPLGRNLSTHQTYPVVA SQ DPHSPFAIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGASVPPFNAFPHAASVYG SQ QFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYSHTPYSSY SQ SEAWRFPNSSLLSSPYYYSSTSRPSAPPTSATAFDHL XX SC translated from EMBL/GenBank/DDBJ #X57487 XX FT 9 133 PF00292; 'Paired box' domain. FT 9 133 SM00351; pax3. FT 9 135 PS51057; PAIRED_2. FT 62 448 PF00478; IMP dehydrogenase / GMP reductase domain. XX IN T09187 Id2; human, Homo sapiens. XX MX M00717 V$PAX8_01. MX M00328 V$PAX8_B. MX M00808 V$PAX_Q6. XX BS R12655. BS R12656. BS R12657. BS R12658. BS R12659. BS R12660. BS R12661. BS R12662. BS R12663. BS R12664. BS R12665. BS R12666. BS R12667. BS R12668. BS R12669. BS R12670. BS R12671. BS R12672. BS R12673. BS R12674. BS R12675. BS R12676. BS R12677. BS R12678. BS R12679. BS R12680. BS R12681. BS R12682. BS R12683. BS R12684. BS R12685. BS R12686. BS R12687. BS R12688. BS R12689. BS R30718. BS R08841. BS R08842. BS R39280. XX DR TRANSPATH: MO000084350. DR EMBL: X57487; DR UniProtKB: Q00288; XX RN [1]; RE0004297. RX PUBMED: 8413205. RA Kozmik Z., Kurzbauer R., Doerfler P., Busslinger M. RT Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties RL Mol. Cell. Biol. 13:6024-6035 (1993). RN [2]; RE0004298. RX PUBMED: 1723950. RA Plachov D., Chowdhury K., Walther C., Simon D., Guenet J. L., Gruss P. RT Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland RL Development 110:643-651 (1990). RN [3]; RE0014313. RX PUBMED: 8625814. RA Song D. L., Chalepakis G., Gruss P., Joyner A. L. RT Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene RL Development 122:627-635 (1996). RN [4]; RE0047963. RX PUBMED: 11134340. RA Roberts E. C., Deed R. W., Inoue T., Norton J. D., Sharrocks A. D. RT Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding. RL Mol. Cell. Biol. 21:524-533 (2001). RN [5]; RE0047965. RX PUBMED: 10748034. RA Kovac C. R., Emelyanov A., Singh M., Ashouian N., Birshtein B. K. RT BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence. RL J. Biol. Chem. 275:16752-16757 (2000). XX //