AC T09184
XX
ID T09184
XX
DT 02.08.2006 (created); jul.
DT 26.06.2012 (updated); hna.
CO Copyright (C), QIAGEN.
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FA Pax-8
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SY mPax-8; mPax8; PAX8.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
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GE G006535 Pax8.
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CL C0017; paired.
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SZ 457 AA; 48.8 kDa (cDNA) (calc.).
XX
SQ MPHNSIRSGHGGLNQLGGAFVNGRPLPEVVRQRIVDLAHQGVRPCDISRQLRVSHGCVSK
SQ ILGRYYETGSIRPGVIGGSKPKVATPKVVEKIGDYKRQNPTMFAWEIRDRLLAEGVCDND
SQ TVPSVSSINRIIRTKVQQPFNLPMDSCVATKSLSPGHTLIPSSAVTPPESPQSDSLGSTY
SQ SINGLLGIAQPGNDNKRKMDDSDQDSCRLSIDSQSSSSGPRKHLRTDTFSQHHLEALECP
SQ FERQHYPEAYASPSHTKGEQGLYPLPLLNSALDDGKATLTSSNTPLGRNLSTHQTYPVVA
SQ DPHSPFAIKQETPELSSSSSTPSSLSSSAFLDLQQVGSGGPAGASVPPFNAFPHAASVYG
SQ QFTGQALLSGREMVGPTLPGYPPHIPTSGQGSYASSAIAGMVAGSEYSGNAYSHTPYSSY
SQ SEAWRFPNSSLLSSPYYYSSTSRPSAPPTSATAFDHL
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SC translated from EMBL/GenBank/DDBJ #X57487
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FT 9 133 
PF00292; 'Paired box' domain.
FT 9 133 
SM00351; pax3.
FT 9 135 
PS51057; PAIRED_2.
FT 62 448 
PF00478; IMP dehydrogenase / GMP reductase domain.
XX
IN T09187 Id2; human, Homo sapiens.
XX
MX M00717 V$PAX8_01.
MX M00328 V$PAX8_B.
MX M00808 V$PAX_Q6.
XX
BS R12655.
BS R12656.
BS R12657.
BS R12658.
BS R12659.
BS R12660.
BS R12661.
BS R12662.
BS R12663.
BS R12664.
BS R12665.
BS R12666.
BS R12667.
BS R12668.
BS R12669.
BS R12670.
BS R12671.
BS R12672.
BS R12673.
BS R12674.
BS R12675.
BS R12676.
BS R12677.
BS R12678.
BS R12679.
BS R12680.
BS R12681.
BS R12682.
BS R12683.
BS R12684.
BS R12685.
BS R12686.
BS R12687.
BS R12688.
BS R12689.
BS R30718.
BS R08841.
BS R08842.
BS R39280.
XX
DR TRANSPATH: MO000084350.
DR EMBL: X57487;
DR UniProtKB: Q00288;
XX
RN [1]; RE0004297.
RX PUBMED: 8413205.
RA Kozmik Z., Kurzbauer R., Doerfler P., Busslinger M.
RT Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties
RL Mol. Cell. Biol. 13:6024-6035 (1993).
RN [2]; RE0004298.
RX PUBMED: 1723950.
RA Plachov D., Chowdhury K., Walther C., Simon D., Guenet J. L., Gruss P.
RT Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
RL Development 110:643-651 (1990).
RN [3]; RE0014313.
RX PUBMED: 8625814.
RA Song D. L., Chalepakis G., Gruss P., Joyner A. L.
RT Two Pax-binding sites are required for early embryonic brain expression of an Engrailed-2 transgene
RL Development 122:627-635 (1996).
RN [4]; RE0047963.
RX PUBMED: 11134340.
RA Roberts E. C., Deed R. W., Inoue T., Norton J. D., Sharrocks A. D.
RT Id helix-loop-helix proteins antagonize pax transcription factor activity by inhibiting DNA binding.
RL Mol. Cell. Biol. 21:524-533 (2001).
RN [5]; RE0047965.
RX PUBMED: 10748034.
RA Kovac C. R., Emelyanov A., Singh M., Ashouian N., Birshtein B. K.
RT BSAP (Pax5)-importin alpha 1 (Rch1) interaction identifies a nuclear localization sequence.
RL J. Biol. Chem. 275:16752-16757 (2000).
XX
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