AC T00525
AS T00519.
XX
ID T00525
XX
DT 26.01.1993 (created); hse.
DT 01.04.2015 (updated); msr.
CO Copyright (C), QIAGEN.
XX
FA MyoD
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SY MEF1; Myf-3; MyoD.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003931 MYOD1; HGNC: MyoD1.
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CL C0010; bHLH; 1.2.2.1.1.
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SF MyoD does not heterodimerize with other myogenic factors [4];
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CP myogenic cells; Cell line SAOS-2, and MG-63 [10].
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FF myogenic transcription factor;
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IN T00204 E12; human, Homo sapiens.
IN T00207 E47; human, Homo sapiens.
IN T00403 Id1; mouse, Mus musculus.
IN T00404 Id2; mouse, Mus musculus.
IN T01212 Id2; human, Homo sapiens.
IN T09187 Id2; human, Homo sapiens.
IN T09198 Id3; mouse, Mus musculus.
IN T00432 ITF-1; human, Homo sapiens.
IN T00433 ITF-2; human, Homo sapiens.
IN T01005 MEF-2A-isoform1; human, Homo sapiens.
IN T02505 MEF-2D-isoform muscle; mouse, Mus musculus.
IN T02506 MEF-2D-isoform non-muscle; mouse, Mus musculus.
IN T01770 mef-2d-isoform1; human, Homo sapiens.
IN T01771 MEF-2DAB; clawed frog, Xenopus laevis.
IN T00526 MyoD; mouse, Mus musculus.
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MX M00804 V$E2A_Q2.
MX M00973 V$E2A_Q6.
MX M01034 V$EBOX_Q6_01.
MX M00001 V$MYOD_01.
MX M00184 V$MYOD_Q6.
MX M00929 V$MYOD_Q6_01.
MX M02100 V$MYOD_Q6_02.
XX
BS R16707.
BS R16711.
BS R16714.
BS R16715.
BS R16718.
BS R16721.
BS R16722.
BS R16726.
BS R26335.
BS R04046.
BS R20212.
BS R02208.
XX
DR TRANSPATH: MO000019612.
DR UniProtKB: P15172; MYOD_HUMAN.
XX
RN [1]; RE0000054.
RX PUBMED: 2155707.
RA Davis R. L., Cheng P.-F., Lassar A. B., Weintraub H.
RT The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation
RL Cell 60:733-746 (1990).
RN [2]; RE0000092.
RX PUBMED: 2493990.
RA Murre C., McCaw P. S., Baltimore D.
RT A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins
RL Cell 56:777-783 (1989).
RN [3]; RE0001484.
RX PUBMED: 2797000.
RA Vaidya T. B., Rhodes S. J., Taparowsky E. J., Konieczny S. F.
RT Fibroblast growth factor and transforming growth factor beta repress transcription of the myogenic regulatory gene MyoD1
RL Mol. Cell. Biol. 9:3576-3579 (1989).
RN [4]; RE0002108.
RX PUBMED: 1945842.
RA Braun T., Arnold H. H.
RT The four helix-loop-helix proteins Myf3-Myf6 exhibit similar hetero-dimerization and DNA binding properties
RL Nucleic Acids Res. 19:5645-5651 (1991).
RN [5]; RE0002654.
RX PUBMED: 3175662.
RA Tapscott S. J., Davis R. L., Thayer M. J., Cheng P., Weintraub H., Lassar A. B.
RT MyoD1: a nuclear phosphoprotein requiring a Myc homology region to convert fibroblasts to myoblasts
RL Science 242:405-411 (1988).
RN [6]; RE0003215.
RX PUBMED: 2748593.
RA Weintraub H., Tapscott S. J., Davis R. L., Thayer M. J., Adam M. A., Lassar A. B., Miller A. D.
RT Activation of muscle-specific genes in pigment, nerve, fat, liver, and fibroblast cell lines by forced expression of MyoD
RL Proc. Natl. Acad. Sci. USA 86:5434-5438 (1989).
RN [7]; RE0003217.
RX PUBMED: 2208280.
RA Thayer M. J., Weintraub H.
RT Activation and repression of myogenesis in somatic cell hybrids: evidence for trans-negative regulation of MyoD in primary fibroblasts
RL Cell 63:23-32 (1990).
RN [8]; RE0039511.
RX PUBMED: 9235903.
RA Anand G., Yin X., Shahidi A. K., Grove L., Prochownik E. V.
RT Novel regulation of the helix-loop-helix protein Id1 by S5a, a subunit of the 26 S proteasome
RL J. Biol. Chem. 272:19140-51 (1997).
RN [9]; RE0048066.
RX PUBMED: 12887892.
RA Fulco M., Schiltz R. L., Iezzi S., King M. T., Zhao P., Kashiwaya Y., Hoffman E., Veech R. L., Sartorelli V.
RT Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state.
RL Mol. Cell 12:51-62 (2003).
RN [10]; RE0048864.
RX PUBMED: 14739291.
RA Sevetson B., Taylor S., Pan Y.
RT Cbfa1/RUNX2 directs specific expression of the sclerosteosis gene (SOST).
RL J. Biol. Chem. 279:13849-13858 (2004).
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