AC T01770
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ID T01770
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DT 18.04.1996 (created); ewi.
DT 23.07.2015 (updated); sla.
CO Copyright (C), QIAGEN.
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FA mef-2d-isoform1
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SY MEF-2D; MEF-2D (514 AA form) (mouse); MEF-2D isoform 1a (mouse); MEF-2D isoform AB; MEF2D; mef2d-isoform1; MEF2DAB.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003970 MEF2D; HGNC: MEF2D.
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CL C0014; MADS; 5.1.1.1.4.1.
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SZ 521 AA; 55.9 kDa (cDNA) (calc.).
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SQ MGRKKIQIQRITDERNRQVTFTKRKFGLMKKAYELSVLCDCEIALIIFNHSNKLFQYAST
SQ DMDKVLLKYTEYNEPHESRTNADIIETLRKKGFNGCDSPEPDGEDSLEQSPLLEDKYRRA
SQ SEELDGLFRRYGSTVPAPNFAMPVTVPVSNQSSLQFSNPSGSLVTPSLVTSSLTDPRLLS
SQ PQQPALQRNSVSPGLPQRPASAGAMLGGDLNSANGACPSPVGNGYVSARASPGLLPVANG
SQ NSLNKVIPAKSPPPPTHSTQLGAPSRKPDLRVITSQAGKGLMHHLTEDHLDLNNAQRLGV
SQ SQSTHSLTTPVVSVATPSLLSQGLPFSSMPTAYNTDYQLTSAELSSLPAFSSPGGLSLGN
SQ VTAWQQPQQPQQPQQPQPPQQQPPQPQQPQPQQPQQPQQPPQQQSHLVPVSLSNLIPGSP
SQ LPHVGAALTVTTHPHISIKSEPVSPSRERSPAPPPPAVFPAARPEPGDGLSSPAGGSYET
SQ GDRDDGRGDFGPTLGLLRPAPEPEAEGSAVKRMRLDTWTLK
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SC conceptually translated from EMBL/GenBank/DDBJ #L16794
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FT 1 60 
SM00432; MADS.
FT 1 61 
PS50066; MADS_BOX_2.
FT 9 59 
PF00319; SRF-type transcription factor (DNA-binding a.
FT 37 326 
PF00478; IMP dehydrogenase / GMP reductase domain.
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SF total of six MEF-2D splice variants are known depending in the presence or absence of either exon A, A' (MEF-2DA_, -2DA'_, or -2D0_) and presence or absence of exon B (MEF-2D_B or -2D_0) [2];
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FF cooperates with MyoD through direct interactions and via binding to either MEF-2-sites or to E-box elements [1];
FF mediates serum induction of the c-jun promoter [3];
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IN T00525 MyoD; human, Homo sapiens.
IN T00526 MyoD; mouse, Mus musculus.
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MX M02026 V$MEF2D_Q4.
MX M00941 V$MEF2_Q6_01.
MX M07424 V$MEF2_Q6_03.
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BS R09235.
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DR TRANSPATH: MO000025911.
DR EMBL: L16794;
DR UniProtKB: Q14814-1;
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RN [1]; RE0004082.
RX PUBMED: 8548800.
RA Molkentin J. D., Black B. L., Martin J. F., Olson E. N.
RT Cooperative activation of muscle gene expression by MEF2 and myogenic bHLH proteins
RL Cell 83:1125-1136 (1995).
RN [2]; RE0004085.
RX PUBMED: 8269842.
RA Breitbart R. E., Liang C. S., Smoot L. B., Laheru D. A., Mahdavi V., Nadal-Ginard B.
RT A fourth human MEF2 transcription factor, hMEF2D, is an early marker of the myogenic lineage
RL Development 118:1095-1106 (1993).
RN [3]; RE0004086.
RX PUBMED: 7760790.
RA Han T.-H., Prywes R.
RT Regulatory role of MEF2D in serum induction of the c-jun promoter
RL Mol. Cell. Biol. 15:2907-2915 (1995).
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