AC T01809
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ID T01809
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DT 14.05.1996 (created); ewi.
DT 09.04.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA Id3
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SY HLH 1R21; HLH462; inhibitor of DNA-binding 3.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005544 ID3; HGNC: ID3.
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CL C0011; HLH.
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SZ 119 AA; 13.0 kDa (cDNA) (calc.), 15 kDa (SDS) [2]
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SQ MKALSPVRGCYEAVCCLSERSLAIARGRGKGPAAEEPLSLLDDMNHCYSRLRELVPGVPR
SQ GTQLSQVEILQRVIDYILDLQVVLAEPAPGPPDGPHLPIQTAELAPELVISNDKRSFCH
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SC Swiss-Prot#Q02535
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FT 25 81 
PS50888; HLH.
FT 27 81 
PF00010; Helix-loop-helix DNA-binding domain.
FT 32 86 
SM00353; finulus.
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SF no basic (=DNA-binding) domain;
SF potential alternative translation initiation may lead to N-terminally extended variants of 148 AA (Heir-1) or 177 AA [1];
SF does not dimerize with Max [2];
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CP adult lung, kidney, adrenal medulla [1].
CN brain [1].
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FF inhibits DNA-binding of MyoD/E12 [2];
FF expression is inversely correlated with that of N-myc gene [1];
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IN T05869 BMAL1; mouse, Mus musculus.
IN T10260 CLOCK; human, Homo sapiens.
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DR TRANSPATH: MO000025943.
DR EMBL: A17548;
DR EMBL: X69111;
DR EMBL: X73428;
DR UniProtKB: Q02535;
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RN [1]; RE0003377.
RX PUBMED: 1628620.
RA Ellmeier W., Aguzzi A., Kleiner E., Kurzbauer R., Weith A.
RT Mutually exclusive expression of a helix-loop-helix gene and N-myc in human neuroblastomas and in normal development
RL EMBO J. 11:2563-2571 (1992).
RN [2]; RE0004175.
RX PUBMED: 8437843.
RA Deed R. W., Bianchi S. M., Atherton G. T., Johnston D., Santibanez-Koref M., Murphy J. J., Norton J. D.
RT An immediate early human gene encodes an Id-like helix-loop-helix protein and is regulated by protein kinase C activation in diverse cell types
RL Oncogene 8:599-607 (1993).
RN [3]; RE0004176.
RX PUBMED: 7828896.
RA Deed R. W., Hirose T., Mitchell E. L., Santibanez-Koref M. F., Norton J. D.
RT Structural organisation and chromosomal mapping of the human Id-3 gene
RL Gene 151:309-314 (1994).
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