TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10625 XX ID T10625 XX DT 10.03.2005 (created); nvo. DT 18.06.2015 (updated); asv. CO Copyright (C), QIAGEN. XX FA Nur77 XX SY GFRP1; N10; NAK1; NGFI; NGFI-B; NR4A1; Nur77; TR3; TR3 orphan receptor. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T10201 COUP-TF1; Mammalia. IN T10310 COUP-TF2; Mammalia. IN T09440 CREB1; mouse, Mus musculus. IN T09920 CREB1; Mammalia. IN T15095 CREB1{pS133}; mouse, Mus musculus. IN T14193 NR1B1; Mammalia. IN T23091 p300; Mammalia. IN T09964 RXR-alpha; Mammalia. IN T11333 TBX19; human, Homo sapiens. XX MX M01217 V$NUR77_Q5. MX M04622 V$NUR77_Q5_01. MX M07426 V$NUR77_Q5_02. XX BS R26030. BS R63893. BS R65121. BS R28188. BS R68449. BS R57682. BS R57346. BS R56128. BS R20622. BS R21612. BS R63894. BS R67232. BS R66061. BS R66062. BS R56633. BS R03313. BS R28683. BS R63420. BS R28685. XX DR TRANSPATH: MO000047501. XX RN [1]; RE0005993. RX PUBMED: 9130711. RA Wu Q., Li Y., Liu R., Agadir A., Lee M.-O., Liu Y., Zhang X.-K. RT Modulation of retinoic acid sensitivity in lung cancer cells through dynamic balance of orphan receptors nur77 and COUP-TF and their heterodimerization RL EMBO J. 16:1656-1669 (1997). RN [2]; RE0027932. RX PUBMED: 11274386. RA Pekarsky Y., Hallas C., Palamarchuk A., Koval A., Bullrich F., Hirata Y., Bichi R., Letofsky J., Croce C. M. RT Akt phosphorylates and regulates the orphan nuclear receptor Nur77. RL Proc. Natl. Acad. Sci. USA 98:3690-4 (2001). RN [3]; RE0031988. RX PUBMED: 14525795. RA Liu D., Jia H., Holmes D. I., Stannard A., Zachary I. RT Vascular endothelial growth factor-regulated gene expression in endothelial cells: KDR-mediated induction of Egr3 and the related nuclear receptors Nur77, Nurr1, and Nor1. RL Arterioscler. Thromb. Vasc. Biol. 23:2002-7 (2003). RN [4]; RE0032043. RX PUBMED: 14729605. RA Choi J. W., Park S. C., Kang G. H., Liu J. O., Youn H. D. RT Nur77 activated by hypoxia-inducible factor-1alpha overproduces proopiomelanocortin in von Hippel-Lindau-mutated renal cell carcinoma. RL Cancer Res. 64:35-9 (2004). RN [5]; RE0037972. RX PUBMED: 12842839. RA Arkenbout E. K., van Bragt M., Eldering E., van Bree C., Grimbergen J. M., Quax P. H., Pannekoek H., de Vries C. J. RT TR3 orphan receptor is expressed in vascular endothelial cells and mediates cell cycle arrest RL Arterioscler. Thromb. Vasc. Biol. 23:1535-40 (2003). RN [6]; RE0039650. RX PUBMED: 12782711. RA Kim S. O., Ono K., Tobias P. S., Han J. RT Orphan nuclear receptor Nur77 is involved in caspase-independent macrophage cell death RL J. Exp. Med. 197:1441-52 (2003). RN [7]; RE0039652. RX PUBMED: 7561876. RA Hirata Y., Whalin M., Ginty D. D., Xing J., Greenberg M. E., Milbrandt J., Guroff G. RT Induction of a nerve growth factor-sensitive kinase that phosphorylates the DNA-binding domain of the orphan nuclear receptor NGFI-B RL J. Neurochem 65:1780-8 (1995). RN [8]; RE0039825. RX PUBMED: 11559707. RA Sohn Y. C., Kwak E., Na Y., Lee J. W., Lee S. K. RT Silencing mediator of retinoid and thyroid hormone receptors and activating signal cointegrator-2 as transcriptional coregulators of the orphan nuclear receptor Nur77 RL J. Biol. Chem. 276:43734-9 (2001). RN [9]; RE0039827. RX PUBMED: 14980220. RA Lin B., Kolluri S. K., Lin F., Liu W., Han Y. H., Cao X., Dawson M. I., Reed J. C., Zhang X. K. RT Conversion of Bcl-2 from protector to killer by interaction with nuclear orphan receptor Nur77/TR3 RL Cell 116:527-40 (2004). RN [10]; RE0039828. RX PUBMED: 10772826. RA Kang H. J., Song M. R., Lee S. K., Shin E. C., Choi Y. H., Kim S. J., Lee J. W., Lee M. O. RT Retinoic acid and its receptors repress the expression and transactivation functions of Nur77: a possible mechanism for the inhibition of apoptosis by retinoic acid RL Exp. Cell Res. 256:545-54 (2000). RN [11]; RE0039851. RX PUBMED: 10973968. RA Stocco C. O., Zhong L., Sugimoto Y., Ichikawa A., Lau L. F., Gibori G. RT Prostaglandin f2alpha -induced expression of 20alpha -hydroxysteroid dehydrogenase involves the transcription factor NUR77 RL J. Biol. Chem. 275:37202-11 (2000). RN [12]; RE0039855. RX PUBMED: 12529383. RA Maira M., Martens C., Batsche E., Gauthier Y., Drouin J. RT Dimer-specific potentiation of NGFI-B (Nur77) transcriptional activity by the protein kinase A pathway and AF-1-dependent coactivator recruitment RL Mol. Cell. Biol. 23:763-76 (2003). RN [13]; RE0039856. RX PUBMED: 9496246. RA Okabe T., Takayanagi R., Adachi M., Imasaki K., Nawata H. RT Nur77, a member of the steroid receptor superfamily, antagonizes negative feedback of ACTH synthesis and secretion by glucocorticoid in pituitary corticotrope cells RL J. Endocrinol. 156:169-75 (1998). RN [14]; RE0041790. RX PUBMED: 14645496. RA Bassett M. H., Suzuki T., Sasano H., White P. C., Rainey W. E. RT The orphan nuclear receptors NURR1 and NGFIB regulate adrenal aldosterone production RL Mol. Endocrinol. 18:279-90 (2004). RN [15]; RE0046235. RX PUBMED: 9858508. RA Dinkel A., Warnatz K., Ledermann B., Rolink A., Zipfel P. F., Burki K., Eibel H. RT The transcription factor early growth response 1 (Egr-1) advances differentiation of pre-B and immature B cells RL J. Exp. Med. 188:2215-24 (1998). RN [16]; RE0048167. RX PUBMED: 15701640. RA Batsche E., Moschopoulos P., Desroches J., Bilodeau S., Drouin J. RT Retinoblastoma and the related pocket protein p107 act as coactivators of NeuroD1 to enhance gene transcription. RL J. Biol. Chem. 280:16088-16095 (2005). RN [17]; RE0063045. RX PUBMED: 12543801. RA Laflamme C., Filion C., Bridge J. A., Ladanyi M., Goldring M. B., Labelle Y. RT The homeotic protein Six3 is a coactivator of the nuclear receptor NOR-1 and a corepressor of the fusion protein EWS/NOR-1 in human extraskeletal myxoid chondrosarcomas. RL Cancer Res. 63:449-454 (2003). 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