AC T17874
XX
ID T17874
XX
DT 04.05.2006 (created); jag.
DT 12.06.2014 (updated); pro.
CO Copyright (C), QIAGEN.
XX
FA LXR-alpha
XX
SY liver X receptor alpha; LXR; LXR A; LXR-A; LXRA; NR1H3; nuclear orphan receptor LXR-alpha.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T15267 DAX1; Mammalia.
IN T10677 FOXO3a; Mammalia.
IN T28267 PGC-1; Mammalia.
IN T23084 SHP; Mammalia.
IN T00759 Sp1; human, Homo sapiens.
IN T21552 SRC-1; Mammalia.
XX
MX M00965 V$DR4_Q2.
MX M00647 V$LXR_Q3.
MX M03795 V$LXR_Q6.
MX M07280 V$NR1NR2_Q3.
XX
BS R62341.
BS R31327.
BS R09971.
BS R19644.
XX
DR TRANSPATH: MO000080952.
XX
RN [1]; RE0023608.
RX PUBMED: 12724417.
RA Kim S. W., Park K., Kwak E., Choi E., Lee S., Ham J., Kang H., Kim J. M., Hwang S. Y., Kong Y. Y., Lee K., Lee J. W.
RT Activating signal cointegrator 2 required for liver lipid metabolism mediated by liver X receptors in mice.
RL Mol. Cell. Biol. 23:3583-3592 (2003).
RN [2]; RE0039064.
RX PUBMED: 10022764.
RA Miyata K. S., McCaw S. E., Meertens L. M., Patel H. V., Rachubinski R. A., Capone J. P.
RT Receptor-interacting protein 140 interacts with and inhibits transactivation by, peroxisome proliferator-activated receptor alpha and liver-X-receptor alpha
RL Mol. Cell. Endocrinol. 146:69-76 (1998).
RN [3]; RE0042891.
RX PUBMED: 12198243.
RA Brendel C., Schoonjans K., Botrugno O. A., Treuter E., Auwerx J.
RT The Small Heterodimer Partner Interacts with the Liver X Receptor alpha and Represses Its Transcriptional Activity
RL Mol. Endocrinol. 16:2065-76 (2002).
RN [4]; RE0048334.
RX PUBMED: 12663743.
RA Hu X., Li S., Wu J., Xia C., Lala D. S.
RT Liver X receptors interact with corepressors to regulate gene expression.
RL Mol. Endocrinol. 17:1019-1026 (2003).
RN [5]; RE0050998.
RX PUBMED: 11504730.
RA Fu X., Menke J. G., Chen Y., Zhou G., MacNaul K. L., Wright S. D., Sparrow C. P., Lund E. G.
RT 27-hydroxycholesterol is an endogenous ligand for liver X receptor in cholesterol-loaded cells.
RL J. Biol. Chem. 276:38378-38387 (2001).
RN [6]; RE0051146.
RX PUBMED: 15649435.
RA Unno A., Takada I., Takezawa S., Oishi H., Baba A., Shimizu T., Tokita A., Yanagisawa J., Kato S.
RT TRRAP as a hepatic coactivator of LXR and FXR function.
RL Biochem. Biophys. Res. Commun. 327:933-938 (2005).
RN [7]; RE0051265.
RX PUBMED: 17296605.
RA Yamamoto T., Shimano H., Inoue N., Nakagawa Y., Matsuzaka T., Takahashi A., Yahagi N., Sone H., Suzuki H., Toyoshima H., Yamada N.
RT Protein kinase A suppresses sterol regulatory element-binding protein-1C expression via phosphorylation of liver X receptor in the liver.
RL J. Biol. Chem. 282:11687-11695 (2007).
RN [8]; RE0051310.
RX PUBMED: 16354658.
RA Albers M., Blume B., Schlueter T., Wright M. B., Kober I., Kremoser C., Deuschle U., Koegl M.
RT A novel principle for partial agonism of liver X receptor ligands. Competitive recruitment of activators and repressors.
RL J. Biol. Chem. 281:4920-4930 (2006).
RN [9]; RE0051608.
RX PUBMED: 11641412.
RA Gan X., Kaplan R., Menke J. G., MacNaul K., Chen Y., Sparrow C. P., Zhou G., Wright S. D., Cai T. Q.
RT Dual mechanisms of ABCA1 regulation by geranylgeranyl pyrophosphate.
RL J. Biol. Chem. 276:48702-48708 (2001).
RN [10]; RE0052791.
RX PUBMED: 17449871.
RA Deng X., Yellaturu C., Cagen L., Wilcox H. G., Park E. A., Raghow R., Elam M. B.
RT Expression of the rat sterol regulatory element-binding protein-1c gene in response to insulin is mediated by increased transactivating capacity of specificity protein 1 (Sp1).
RL J. Biol. Chem. 282:17517-17529 (2007).
XX
//