TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T09516 XX ID T09516 XX DT 10.03.2005 (created); nvo. DT 13.05.2014 (updated); jmh. CO Copyright (C), QIAGEN. XX FA STAT6 XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T15118 CBP; Mammalia. IN T10446 GR; Mammalia. IN T23091 p300; Mammalia. IN T08171 PSF; human, Homo sapiens. IN T21552 SRC-1; Mammalia. IN T23076 STAT1; Mammalia. IN T16670 STAT2; Mammalia. XX MX M00494 V$STAT6_01. MX M00500 V$STAT6_02. MX M07066 V$STAT6_Q4. MX M00223 V$STAT_01. MX M00777 V$STAT_Q6. XX BS R41414. BS R41415. BS R61736. BS R11183. BS R13215. BS R19668. BS R26945. XX DR TRANSPATH: MO000047089. XX RN [1]; RE0022264. RX PUBMED: 10373589. RA Gingras S., Simard J., Groner B., Pfitzner E. RT p300/CBP is required for transcriptional induction by interleukin-4 and interacts with Stat6. RL Nucleic Acids Res. 27:2722-2729 (1999). RN [2]; RE0022374. RX PUBMED: 12234934. RA Yang J., Aittomaki S., Pesu M., Carter K., Saarinen J., Kalkkinen N., Kieff E., Silvennoinen O. RT Identification of p100 as a coactivator for STAT6 that bridges STAT6 with RNA polymerase II. RL EMBO J. 21:4950-4958 (2002). RN [3]; RE0022484. RX PUBMED: 11574547. RA Litterst C. M., Pfitzner E. RT Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. RL J. Biol. Chem. 276:45713-45721 (2001). RN [4]; RE0026445. RX PUBMED: 10820389. RA Oki S., Otsuki N., Kohsaka T., Azuma M. RT Stat6 activation and Th2 cell proliferation driven by CD28 signals. RL Eur. J. Immunol. 30:1416-24 (2000). RN [5]; RE0026476. RX PUBMED: 10861028. RA Zhang S., Lukacs N. W., Lawless V. A., Kunkel S. L., Kaplan M. H. RT Cutting edge: differential expression of chemokines in Th1 and Th2 cells is dependent on stat6 but not stat4 RL J. Immunol. 165:10-4 (2000). RN [6]; RE0028266. RX PUBMED: 7635985. RA Fenghao X., Saxon A., Nguyen A., Ke Z., Diaz-Sanchez D., Nel A. RT Interleukin 4 activates a signal transducer and activator of transcription (Stat) protein which interacts with an interferon-gamma activation site-like sequence upstream of the I epsilon exon in a human B cell line. Evidence for the involvement of Janus kinase 3 and interleukin-4 Stat. RL J. Clin. Invest. 96:907-14 (1995). RN [7]; RE0032378. RX PUBMED: 15242529. RA Ke B., Shen X. D., Gao F., Busuttil R. W., Kupiec-Weglinski J. W. RT Interleukin 13 gene transfer in liver ischemia and reperfusion injury: role of Stat6 and TLR4 pathways in cytoprotection. RL Hum. Gene Ther. 15:691-8 (2004). RN [8]; RE0032769. RX PUBMED: 15004182. RA Blanchard C., Durual S., Estienne M., Bouzakri K., Heim M. H., Blin N., Cuber J. C. RT IL-4 and IL-13 up-regulate intestinal trefoil factor expression: requirement for STAT6 and de novo protein synthesis. RL J. Immunol. 172:3775-83 (2004). RN [9]; RE0032995. RX PUBMED: 15145939. RA Arimura A., vn Peer M., Schroder A. J., Rothman P. B. RT The transcriptional co-activator p/CIP (NCoA-3) is up-regulated by STAT6 and serves as a positive regulator of transcriptional activation by STAT6. RL J. Biol. Chem. 279:31105-12 (2004). RN [10]; RE0041144. RX PUBMED: 12517954. RA Shankaranarayanan P., Nigam S. RT IL-4 induces apoptosis in A549 lung adenocarcinoma cells: evidence for the pivotal role of 15-hydroxyeicosatetraenoic acid binding to activated peroxisome proliferator-activated receptor gamma transcription factor RL J. Immunol. 170:887-94 (2003). RN [11]; RE0041148. RX PUBMED: 12194977. RA Wong G. W., Foster P. S., Yasuda S., Qi J. C., Mahalingam S., Mellor E. A., Katsoulotos G., Li L., Boyce J. A., Krilis S. A., Stevens R. L. RT Biochemical and functional characterization of human transmembrane tryptase (TMT)/tryptase gamma. TMT is an exocytosed mast cell protease that induces airway hyperresponsiveness in vivo via an interleukin-13/interleukin-4 receptor alpha/signal transducer and activator of transcription (STAT) 6-dependent pathway RL J. Biol. Chem. 277:41906-15 (2002). RN [12]; RE0041153. RX PUBMED: 10880399. RA Kato A., Yoshidome H., Edwards M. J., Lentsch A. B. RT Regulation of liver inflammatory injury by signal transducer and activator of transcription-6 RL Am. J. Pathol. 157:297-302 (2000). RN [13]; RE0042403. RX PUBMED: 14757047. RA Razeto A., Ramakrishnan V., Litterst C. M., Giller K., Griesinger C., Carlomagno T., Lakomek N., Heimburg T., Lodrini M., Pfitzner E., Becker S. RT Structure of the NCoA-1/SRC-1 PAS-B domain bound to the LXXLL motif of the STAT6 transactivation domain RL J. Mol. Biol. 336:319-29 (2004). RN [14]; RE0043466. RX PUBMED: 11544308. RA Hoeck J., Woisetschlager M. RT Activation of eotaxin-3/ccl26 gene expression in human dermal fibroblasts is mediated by stat6 RL J. Immunol. 167:3216-22 (2001). RN [15]; RE0043832. RX PUBMED: 9550426. RA Dickensheets H. L., Donnelly R. P. RT IFN-gamma and IL-10 inhibit induction of IL-1 receptor type I and type II gene expression by IL-4 and IL-13 in human monocytes RL J. Immunol. 159:6226-33 (1997). RN [16]; RE0045288. RX PUBMED: 9852261. RA Murata T., Obiri N. I., Puri R. K. RT Structure of and signal transduction through interleukin-4 and interleukin-13 receptors (review) RL Int. J. Mol. Med. 1:551-7 (1998). XX //