AC T16670
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ID T16670
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DT 10.03.2005 (created); nvo.
DT 12.06.2014 (updated); spk.
CO Copyright (C), QIAGEN.
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FA STAT2
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T16987 BRG1; Mammalia.
IN T15118 CBP; Mammalia.
IN T21852 HDAC1; Mammalia.
IN T34788 IRF-9; Mammalia.
IN T23091 p300; Mammalia.
IN T23076 STAT1; Mammalia.
IN T14458 STAT3; Mammalia.
IN T16672 STAT4; Mammalia.
IN T09516 STAT6; Mammalia.
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MX M00223 V$STAT_01.
MX M00777 V$STAT_Q6.
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DR TRANSPATH: MO000047450.
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RN [1]; RE0006163.
RX PUBMED: 8848048.
RA Bhattacharya S., Eckner R., Grossman S., Oldread E., Arany Z., D Andrea A., Livingston D. M.
RT Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha
RL Nature 383:344-347 (1996).
RN [2]; RE0034096.
RX PUBMED: 15356135.
RA Kamiya S., Owaki T., Morishima N., Fukai F., Mizuguchi J., Yoshimoto T.
RT An indispensable role for STAT1 in IL-27-induced T-bet expression but not proliferation of naive CD4+ T cells.
RL J. Immunol. 173:3871-7 (2004).
RN [3]; RE0037500.
RX PUBMED: 12509459.
RA Lau J. F., Nusinzon I., Burakov D., Freedman L. P., Horvath C. M.
RT Role of metazoan mediator proteins in interferon-responsive transcription
RL Mol. Cell. Biol. 23:620-8 (2003).
RN [4]; RE0039388.
RX PUBMED: 12925694.
RA Wang J., Pham-Mitchell N., Schindler C., Campbell I. L.
RT Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain
RL J. Clin. Invest. 112:535-43 (2003).
RN [5]; RE0041242.
RX PUBMED: 10881177.
RA Farrar J. D., Smith J. D., Murphy T. L., Leung S., Stark G. R., Murphy K. M.
RT Selective loss of type I interferon-induced STAT4 activation caused by a minisatellite insertion in mouse Stat2
RL Nat. Immunol. 1:65-9 (2000).
RN [6]; RE0041993.
RX PUBMED: 15123634.
RA Klampfer L., Huang J., Swaby L. A., Augenlicht L.
RT Requirement of histone deacetylase activity for signaling by STAT1
RL J. Biol. Chem. 279:30358-68 (2004).
RN [7]; RE0044204.
RX PUBMED: 12048190.
RA Fagerlund R., Melen K., Kinnunen L., Julkunen I.
RT Arginine/lysine-rich nuclear localization signals mediate interactions between dimeric STATs and importin alpha 5
RL J. Biol. Chem. 277:30072-8 (2002).
RN [8]; RE0044343.
RX PUBMED: 10860992.
RA Lau J. F., Parisien J. P., Horvath C. M.
RT Interferon regulatory factor subcellular localization is determined by a bipartite nuclear localization signal in the DNA-binding domain and interaction with cytoplasmic retention factors
RL Proc. Natl. Acad. Sci. USA 97:7278-83 (2000).
RN [9]; RE0044344.
RX PUBMED: 9677371.
RA Krishnan K., Singh B., Krolewski J. J.
RT Identification of amino acid residues critical for the Src-homology 2 domain-dependent docking of Stat2 to the interferon alpha receptor
RL J. Biol. Chem. 273:19495-501 (1998).
RN [10]; RE0053870.
RX PUBMED: 17923090.
RA Tang X., Gao J. S., Guan Y. J., McLane K. E., Yuan Z. L., Ramratnam B., Chin Y. E.
RT Acetylation-dependent signal transduction for type I interferon receptor.
RL Cell 131:93-105 (2007).
RN [11]; RE0065792.
RX PUBMED: 17442890.
RA Scarzello A. J., Romero-Weaver A. L., Maher S. G., Veenstra T. D., Zhou M., Qin A., Donnelly R. P., Sheikh F., Gamero A. M.
RT A Mutation in the SH2 domain of STAT2 prolongs tyrosine phosphorylation of STAT1 and promotes type I IFN-induced apoptosis.
RL Mol. Biol. Cell 18:2455-2462 (2007).
RN [12]; RE0066251.
RX PUBMED: 11786546.
RA Nguyen V. P., Saleh A. Z., Arch A. E., Yan H., Piazza F., Kim J., Krolewski J. J.
RT Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling.
RL J. Biol. Chem. 277:9713-9721 (2002).
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