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TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN


AC T16015 XX ID T16015 XX DT 10.03.2005 (created); nvo. DT 16.01.2015 (updated); spk. CO Copyright (C), QIAGEN. XX FA ER-beta XX SY estradiol receptor; estrogen receptor beta. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T23080 AhR; Mammalia. IN T15601 AR; Mammalia. IN T10818 arnt; Mammalia. IN T22203 CREB; mouse, Mus musculus. IN T09637 ER-alpha; Mammalia. IN T08641 NCOR1-isoform1; mouse, Mus musculus. IN T23084 SHP; Mammalia. IN T02420 Sox-13; mouse, Mus musculus. IN T08326 Sp1; Mammalia. IN T21552 SRC-1; Mammalia. IN T04638 SRC3; mouse, Mus musculus. IN T09095 SREBP-1; Mammalia. IN T16692 TCF-1; Mammalia. IN T16010 TCF-4; Mammalia. XX MX M01875 V$ERBETA_Q5. MX M03821 V$ERBETA_Q5_01. MX M00959 V$ER_Q6_02. XX BS R18539. BS R18540. XX DR TRANSPATH: MO000047138. XX RN [1]; RE0020843. RX PUBMED: 11032808. RA Migliaccio A., Castoria G., Di Domenico M., de Falco A., Bilancio A., Lombardi M., Barone M. V., Ametrano D., Zannini M. S., Abbondanza C., Auricchio F. RT Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation RL EMBO J. 19:5406-5417 (2000). RN [2]; RE0022566. RX PUBMED: 11368516. RA Klinge C. M., Jernigan S. C., Risinger K. E., Lee J. E., Tyulmenkov V. V., Falkner K. C., Prough R. A. RT Short heterodimer partner (SHP) orphan nuclear receptor inhibits the transcriptional activity of aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT). RL Arch. Biochem. Biophys. 390:64-70 (2001). RN [3]; RE0023544. RX PUBMED: 11522780. RA El-Tanani M., Fernig D. G., Barraclough R., Green C., Rudland P. RT Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors. RL J. Biol. Chem. 276:41675-41682 (2001). RN [4]; RE0031456. RX PUBMED: 14745018. RA Strom A., Hartman J., Foster J. S., Kietz S., Wimalasena J., Gustafsson J. A. RT Estrogen receptor beta inhibits 17beta-estradiol-stimulated proliferation of the breast cancer cell line T47D. RL Proc. Natl. Acad. Sci. USA 101:1566-71 (2004). RN [5]; RE0037587. RX PUBMED: 10908561. RA Montano M. M., Wittmann B. M., Bianco N. R. RT Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity RL J. Biol. Chem. 275:34306-13 (2000). RN [6]; RE0037650. RX PUBMED: 12039952. RA Qi C., Chang J., Zhu Y., Yeldandi A. V., Rao S. M., Zhu Y. J. RT Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha RL J. Biol. Chem. 277:28624-30 (2002). RN [7]; RE0038356. RX PUBMED: 11799247. RA Zhu Y., Bian Z., Lu P., Karas R. H., Bao L., Cox D., Hodgin J., Shaul P. W., Thoren P., Smithies O., Gustafsson J. A., Mendelsohn M. E. RT Abnormal vascular function and hypertension in mice deficient in estrogen receptor beta RL Science 295:505-8 (2002). RN [8]; RE0038613. RX PUBMED: 12021179. RA Lopez D., Sanchez M. D., Shea-Eaton W., McLean M. P. RT Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A RL Endocrinology 143:2155-68 (2002). RN [9]; RE0039780. RX PUBMED: 14625289. RA Tujague M., Thomsen J. S., Mizuki K., Sadek C. M., Gustafsson J. A. RT The focal adhesion protein vinexin alpha regulates the phosphorylation and activity of estrogen receptor alpha RL J. Biol. Chem. 279:9255-63 (2004). RN [10]; RE0039795. RX PUBMED: 14702340. RA Masuyama H., Hiramatsu Y. RT Involvement of suppressor for Gal 1 in the ubiquitin/proteasome-mediated degradation of estrogen receptors RL J. Biol. Chem. 279:12020-6 (2004). RN [11]; RE0040648. RX PUBMED: 10681591. RA Leo C., Li H., Chen J. D. RT Differential mechanisms of nuclear receptor regulation by receptor-associated coactivator 3 RL J. Biol. Chem. 275:5976-82 (2000). RN [12]; RE0041011. RX PUBMED: 11061546. RA Chiang C. H., Cheng K. W., Igarashi S., Nathwani P. S., Leung P. C. RT Hormonal regulation of estrogen receptor alpha and beta gene expression in human granulosa-luteal cells in vitro RL J. Clin. Endocrinol. Metab. 85:3828-39 (2000). RN [13]; RE0041166. RX PUBMED: 12130554. RA Somponpun S., Sladek C. D. RT Role of estrogen receptor-beta in regulation of vasopressin and oxytocin release in vitro RL Endocrinology 143:2899-904 (2002). RN [14]; RE0041217. RX PUBMED: 11380688. RA Erlandsson M. C., Ohlsson C., Gustafsson J. A., Carlsten H. RT Role of oestrogen receptors alpha and beta in immune organ development and in oestrogen-mediated effects on thymus RL Immunology 103:17-25 (2001). RN [15]; RE0041228. RX PUBMED: 15208676. RA Hou Y. F., Yuan S. T., Li H. C., Wu J., Lu J. S., Liu G., Lu L. J., Shen Z. Z., Ding J., Shao Z. M. RT ERbeta exerts multiple stimulative effects on human breast carcinoma cells RL Oncogene 23:5799-806 (2004). RN [16]; RE0041229. RX PUBMED: 11867769. RA Kang Y. K., Guermah M., Yuan C. X., Roeder R. G. RT The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro RL Proc. Natl. Acad. Sci. USA 99:2642-7 (2002). RN [17]; RE0041230. RX PUBMED: 10747867. RA Kobayashi Y., Kitamoto T., Masuhiro Y., Watanabe M., Kase T., Metzger D., Yanagisawa J., Kato S. RT p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains RL J. Biol. Chem. 275:15645-51 (2000). RN [18]; RE0041232. RX PUBMED: 12370428. RA Weihua Z., Lathe R., Warner M., Gustafsson J. A. RT An endocrine pathway in the prostate, ERbeta, AR, 5alpha-androstane-3beta,17beta-diol, and CYP7B1, regulates prostate growth RL Proc. Natl. Acad. Sci. USA 99:13589-94 (2002). RN [19]; RE0041234. RX PUBMED: 14739282. RA Melvin V. S., Harrell C., Adelman J. S., Kraus W. L., Churchill M., Edwards D. P. RT The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB RL J. Biol. Chem. 279:14763-71 (2004). RN [20]; RE0041807. RX PUBMED: 11113208. RA Sauve F., McBroom L. D., Gallant J., Moraitis A. N., Labrie F., Giguere V. RT CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant RL Mol. Cell. Biol. 21:343-53 (2001). RN [21]; RE0041982. RX PUBMED: 12829806. RA Otsuki M., Gao H., Dahlman-Wright K., Ohlsson C., Eguchi N., Urade Y., Gustafsson J. A. RT Specific regulation of lipocalin-type prostaglandin D synthase in mouse heart by estrogen receptor beta RL Mol. Endocrinol. 17:1844-55 (2003). RN [22]; RE0042014. RX PUBMED: 12943696. RA Deblois G., Giguere V. RT Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation RL J. Steroid Biochem. Mol. Biol. 85:123-31 (2003). RN [23]; RE0042088. RX PUBMED: 10936673. RA Shao Z. M., Radziszewski W. J., Barsky S. H. RT Tamoxifen enhances myoepithelial cell suppression of human breast carcinoma progression in vitro by two different effector mechanisms RL Cancer Lett. 157:133-44 (2000). RN [24]; RE0042102. RX PUBMED: 11078914. RA Nakayama Y., Sakamoto H., Satoh K., Yamamoto T. RT Tamoxifen and gonadal steroids inhibit colon cancer growth in association with inhibition of thymidylate synthase, survivin and telomerase expression through estrogen receptor beta mediated system RL Cancer Lett. 161:63-71 (2000). RN [25]; RE0042103. RX PUBMED: 12810572. RA Frasor J., Barnett D. H., Danes J. M., Hess R., Parlow A. F., Katzenellenbogen B. S. RT Response-specific and ligand dose-dependent modulation of estrogen receptor (ER) alpha activity by ERbeta in the uterus RL Endocrinology 144:3159-66 (2003). RN [26]; RE0042118. RX PUBMED: 14583652. RA Dorling A. A., Todman M. G., Korach K. S., Herbison A. E. RT Critical role for estrogen receptor alpha in negative feedback regulation of gonadotropin-releasing hormone mRNA expression in the female mouse RL Neuroendocrinology 78:204-9 (2003). RN [27]; RE0042119. RX PUBMED: 11145749. RA Lei Z. M., Mishra S., Zou W., Xu B., Foltz M., Li X., Rao C. V. RT Targeted Disruption of Luteinizing Hormone/Human Chorionic Gonadotropin Receptor Gene RL Mol. Endocrinol. 15:184-200 (2001). RN [28]; RE0043614. RX PUBMED: 12787135. RA Kanda N., Watanabe S. RT 17Beta-estradiol inhibits MCP-1 production in human keratinocytes RL J. Invest. Dermatol 120:1058-66 (2003). RN [29]; RE0046748. RX PUBMED: 12754377. RA Brunnberg S., Pettersson K., Rydin E., Matthews J., Hanberg A., Pongratz I. RT The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription RL Proc. Natl. Acad. Sci. USA 100:6517-22 (2003). RN [30]; RE0048863. RX PUBMED: 12904255. RA Webb P., Valentine C., Nguyen P., Price RH J. r., Marimuthu A., West B. L., Baxter J. D., Kushner P. J. RT ERbeta Binds N-CoR in the Presence of Estrogens via an LXXLL-like Motif in the N-CoR C-terminus. RL Nucl. Recept. 1:4 (2003). XX //