TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T04638 XX ID T04638 XX DT 24.07.2001 (created); mas. DT 10.01.2014 (updated); pos. CO Copyright (C), QIAGEN. XX FA SRC3 XX SY NCOA-3; NCOA3; nuclear receptor coactivator 3; p/CIP; P300/CBP/co-integrator protein; SRC-3; steroid receptor coactivator-3. XX OS mouse, Mus musculus OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae XX GE G002756 Ncoa3. XX CL C0010; bHLH; XX SF coactivator for the steroid hormone receptor superfamily [2]; SF contains several NR box motifs within the nuclear receptor interacting domain: important for interaction with cognate nuclear receptors in ligand-bound status (via AF-2 domain) [2] [1]; XX IN T01795 AhR; human, Homo sapiens. IN T01318 CBP; mouse, Mus musculus. IN T00259 ER-alpha; mouse, Mus musculus. IN T16015 ER-beta; Mammalia. IN T06175 ERR2; mouse, Mus musculus. XX DR TRANSPATH: MO000028471. DR UniProtKB: O09000; XX RN [1]; RE0006908. RX PUBMED: 9430642. RA Voegel J. J., Heine M. J., Tini M., Vivat V., Chambon P., Gronemeyer H. RT The coactivator TIF2 contains three nuclear receptor-binding motifs and mediates transactivation through CBP binding-dependent and -independent pathways RL EMBO J. 17:507-519 (1998). RN [2]; RE0016476. RX PUBMED: 10713439. RA Leo C., Chen J. D. RT The SRC family of nuclear receptor coactivators RL Gene 245:1-11 (2000). RN [3]; RE0048217. RX PUBMED: 11971985. RA Wu R. C., Qin J., Hashimoto Y., Wong J., Xu J., Tsai S. Y., Tsai M. J., O'Malley B. W. RT Regulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase. RL Mol. Cell. Biol. 22:3549-3561 (2002). RN [4]; RE0065548. RX PUBMED: 19574399. RA Chen J., An B. S., Cheng L., Hammond G. L., Leung P. C. RT Gonadotropin-releasing hormone-mediated phosphorylation of estrogen receptor-alpha contributes to fosB expression in mouse gonadotrophs. RL Endocrinology 150:4583-4593 (2009). XX //