AC T09637
XX
ID T09637
XX
DT 10.03.2005 (created); nvo.
DT 12.01.2016 (updated); mom.
CO Copyright (C), QIAGEN.
XX
FA ER-alpha
XX
SY ER; ESR1; estradiol receptor; estrogen receptor; estrogen receptor alpha; NR3A1.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T15601 AR; Mammalia.
IN T10818 arnt; Mammalia.
IN T08887 brca1-isoform1; human, Homo sapiens.
IN T15204 brca1; Mammalia.
IN T16987 BRG1; Mammalia.
IN T14807 Brn-3a; Mammalia.
IN T16228 Brn-3b; Mammalia.
IN T18378 CBP; human, Homo sapiens.
IN T10259 Clock-L; mouse, Mus musculus.
IN T18364 Clock; Mammalia.
IN T10201 COUP-TF1; Mammalia.
IN T08300 ER-alpha-L; human, Homo sapiens.
IN T00261 ER-alpha; human, Homo sapiens.
IN T16015 ER-beta; Mammalia.
IN T14067 FOXO1A; Mammalia.
IN T10677 FOXO3a; Mammalia.
IN T16596 foxo4; Mammalia.
IN T21852 HDAC1; Mammalia.
IN T00992 Hsp90; human, Homo sapiens.
IN T10864 islet1; Mammalia.
IN T02187 MAT1; human, Homo sapiens.
IN T10759 MTA-1; human, Homo sapiens.
IN T14193 NR1B1; Mammalia.
IN T21984 p300; human, Homo sapiens.
IN T23091 p300; Mammalia.
IN T28267 PGC-1; Mammalia.
IN T10397 RelA-p65; Mammalia.
IN T16466 SAFB1; Mammalia.
IN T23084 SHP; Mammalia.
IN T09538 Smad3; Mammalia.
IN T13998 Smad4; Mammalia.
IN T08326 Sp1; Mammalia.
IN T08256 SRC-1A; human, Homo sapiens.
IN T09095 SREBP-1; Mammalia.
IN T16692 TCF-1; Mammalia.
IN T16010 TCF-4; Mammalia.
IN T19142 TR2; human, Homo sapiens.
IN T02740 TR4; human, Homo sapiens.
IN T10019 TR4; Mammalia.
IN T00900 WT1 I -KTS; human, Homo sapiens.
XX
MX M01801 V$ERALPHA_01.
MX M07283 V$ERALPHA_Q4.
MX M03547 V$ERALPHA_Q6_01.
MX M03820 V$ERALPHA_Q6_02.
MX M00191 V$ER_Q6.
MX M00959 V$ER_Q6_02.
XX
BS R02150.
BS R03564.
BS R24995.
BS R19794.
BS R21805.
BS R21806.
BS R21807.
BS R62297.
BS R30366.
BS R30367.
BS R18539.
BS R18540.
BS R24739.
BS R25022.
BS R24877.
BS R26515.
BS R33045.
BS R63864.
BS R26516.
BS R24516.
BS R30524.
BS R62872.
BS R25015.
BS R67339.
BS R14194.
BS R72617.
BS R72618.
BS R72619.
BS R64897.
BS R64899.
BS R36387.
BS R30089.
BS R73870.
BS R01267.
BS R33783.
BS R33786.
BS R33788.
BS R23732.
BS R02665.
BS R28284.
BS R35121.
XX
DR TRANSPATH: MO000046875.
DR TRANSCOMPEL: C00019.
DR TRANSCOMPEL: C00363.
XX
RN [1]; RE0013078.
RX PUBMED: 8524784.
RA Zeiner M., Gehring U.
RT A protein that interacts with members of the nuclear hormone receptor family: Identification and cDNA cloning
RL Proc. Natl. Acad. Sci. USA 92:11465-11469 (1995).
RN [2]; RE0020843.
RX PUBMED: 11032808.
RA Migliaccio A., Castoria G., Di Domenico M., de Falco A., Bilancio A., Lombardi M., Barone M. V., Ametrano D., Zannini M. S., Abbondanza C., Auricchio F.
RT Steroid-induced androgen receptor-oestradiol receptor beta-Src complex triggers prostate cancer cell proliferation
RL EMBO J. 19:5406-5417 (2000).
RN [3]; RE0022566.
RX PUBMED: 11368516.
RA Klinge C. M., Jernigan S. C., Risinger K. E., Lee J. E., Tyulmenkov V. V., Falkner K. C., Prough R. A.
RT Short heterodimer partner (SHP) orphan nuclear receptor inhibits the transcriptional activity of aryl hydrocarbon receptor (AHR)/AHR nuclear translocator (ARNT).
RL Arch. Biochem. Biophys. 390:64-70 (2001).
RN [4]; RE0023544.
RX PUBMED: 11522780.
RA El-Tanani M., Fernig D. G., Barraclough R., Green C., Rudland P.
RT Differential modulation of transcriptional activity of estrogen receptors by direct protein-protein interactions with the T cell factor family of transcription factors.
RL J. Biol. Chem. 276:41675-41682 (2001).
RN [5]; RE0027542.
RX PUBMED: 10681512.
RA Saville B., Wormke M., Wang F., Nguyen T., Enmark E., Kuiper G., Gustafsson J. A., Safe S.
RT Ligand-, cell-, and estrogen receptor subtype (alpha/beta)-dependent activation at GC-rich (Sp1) promoter elements.
RL J. Biol. Chem. 275:5379-87 (2000).
RN [6]; RE0028944.
RX PUBMED: 11435445.
RA Schuur E. R., Loktev A. V., Sharma M., Sun Z., Roth R. A., Weigel R. J.
RT Ligand-dependent interaction of estrogen receptor-alpha with members of the forkhead transcription factor family.
RL J. Biol. Chem. 276:33554-60 (2001).
RN [7]; RE0028965.
RX PUBMED: 11581164.
RA Yahata T., Shao W., Endoh H., Hur J., Coser K. R., Sun H., Ueda Y., Kato S., Isselbacher K. J., Brown M., Shioda T.
RT Selective coactivation of estrogen-dependent transcription by CITED1 CBP/p300-binding protein.
RL Genes Dev. 15:2598-612 (2001).
RN [8]; RE0029603.
RX PUBMED: 11971969.
RA Shao W., Halachmi S., Brown M.
RT ERAP140, a conserved tissue-specific nuclear receptor coactivator.
RL Mol. Cell. Biol. 22:3358-72 (2002).
RN [9]; RE0033355.
RX PUBMED: 15039427.
RA Finlay G. A., York B., Karas R. H., Fanburg B. L., Zhang H., Kwiatkowski D. J., Noonan D. J.
RT Estrogen-induced smooth muscle cell growth is regulated by tuberin and associated with altered activation of platelet-derived growth factor receptor-beta and ERK-1/2.
RL J. Biol. Chem. 279:23114-22 (2004).
RN [10]; RE0034397.
RX PUBMED: 15318176.
RA Morelli C., Garofalo C., Sisci D., del Rincon S., Cascio S., Tu X., Vecchione A., Sauter E. R., Miller W. H. Jr, Surmacz E.
RT Nuclear insulin receptor substrate 1 interacts with estrogen receptor alpha at ERE promoters.
RL Oncogene 23:7517-26 (2004).
RN [11]; RE0034831.
RX PUBMED: 11696545.
RA Saville B., Poukka H., Wormke M., Janne O. A., Palvimo J. J., Stoner M., Samudio I., Safe S.
RT Cooperative coactivation of estrogen receptor alpha in ZR-75 human breast cancer cells by SNURF and TATA-binding protein.
RL J. Biol. Chem. 277:2485-97 (2002).
RN [12]; RE0035802.
RX PUBMED: 12374744.
RA Wang R. A., Mazumdar A., Vadlamudi R. K., Kumar R.
RT P21-activated kinase-1 phosphorylates and transactivates estrogen receptor-alpha and promotes hyperplasia in mammary epithelium.
RL EMBO J. 21:5437-5447 (2002).
RN [13]; RE0035947.
RX PUBMED: 12527756.
RA Talukder A. H., Mishra S. K., Mandal M., Balasenthil S., Mehta S., Sahin A. A., Barnes C. J., Kumar R.
RT MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions.
RL J. Biol. Chem. 278:11676-11685 (2003).
RN [14]; RE0035961.
RX PUBMED: 9628887.
RA Abbondanza C., Rossi V., Roscigno A., Gallo L., Belsito A., Piluso G., Medici N., Nigro V., Molinari A. M., Moncharmont B., Puca G. A.
RT Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell.
RL J. Cell Biol. 141:1301-1310 (1998).
RN [15]; RE0035985.
RX PUBMED: 9448000.
RA Budhram-Mahadeo V., Parker M., Latchman D. S.
RT POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element.
RL Mol. Cell. Biol. 18:1029-1041 (1998).
RN [16]; RE0035988.
RX PUBMED: 11043578.
RA Gay F., Anglade I., Gong Z., Salbert G.
RT The LIM/homeodomain protein islet-1 modulates estrogen receptor functions.
RL Mol. Endocrinol. 14:1627-1648 (2000).
RN [17]; RE0036149.
RX PUBMED: 9099865.
RA Ichinose H., Garnier J. M., Chambon P., Losson R.
RT Ligand-dependent interaction between the estrogen receptor and the human homologues of SWI2/SNF2.
RL Gene 188:95-100 (1997).
RN [18]; RE0037587.
RX PUBMED: 10908561.
RA Montano M. M., Wittmann B. M., Bianco N. R.
RT Identification and characterization of a novel factor that regulates quinone reductase gene transcriptional activity
RL J. Biol. Chem. 275:34306-13 (2000).
RN [19]; RE0037650.
RX PUBMED: 12039952.
RA Qi C., Chang J., Zhu Y., Yeldandi A. V., Rao S. M., Zhu Y. J.
RT Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha
RL J. Biol. Chem. 277:28624-30 (2002).
RN [20]; RE0037850.
RX PUBMED: 11854298.
RA Kressler D., Schreiber S. N., Knutti D., Kralli A.
RT The PGC-1-related protein PERC is a selective coactivator of estrogen receptor alpha
RL J. Biol. Chem. 277:13918-25 (2002).
RN [21]; RE0037852.
RX PUBMED: 11792840.
RA Ting H. J., Yeh S., Nishimura K., Chang C.
RT Supervillin associates with androgen receptor and modulates its transcriptional activity
RL Proc. Natl. Acad. Sci. USA 99:661-6 (2002).
RN [22]; RE0037930.
RX PUBMED: 14760094.
RA Spychala J., Lazarowski E., Ostapkowicz A., Ayscue L. H., Jin A., Mitchell B. S.
RT Role of estrogen receptor in the regulation of ecto-5'-nucleotidase and adenosine in breast cancer
RL Clin. Cancer Res. 10:708-17 (2004).
RN [23]; RE0038355.
RX PUBMED: 12827494.
RA Liang M., Ekblad E., Lydrup M. L., Nilsson B. O.
RT Combined lack of estrogen receptors alpha and beta affects vascular iNOS protein expression
RL Cell Tissue Res. 313:63-70 (2003).
RN [24]; RE0038613.
RX PUBMED: 12021179.
RA Lopez D., Sanchez M. D., Shea-Eaton W., McLean M. P.
RT Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A
RL Endocrinology 143:2155-68 (2002).
RN [25]; RE0039129.
RX PUBMED: 11850827.
RA Moll F., Katsaros D., Lazennec G., Hellio N., Roger P., Giacalone P. L., Chalbos D., Maudelonde T., Rochefort H., Pujol P.
RT Estrogen induction and overexpression of fibulin-1C mRNA in ovarian cancer cells
RL Oncogene 21:1097-107 (2002).
RN [26]; RE0039487.
RX PUBMED: 12810571.
RA Oltra E., Pfeifer I., Werner R.
RT Ini, a small nuclear protein that enhances the response of the connexin43 gene to estrogen
RL Endocrinology 144:3148-58 (2003).
RN [27]; RE0039780.
RX PUBMED: 14625289.
RA Tujague M., Thomsen J. S., Mizuki K., Sadek C. M., Gustafsson J. A.
RT The focal adhesion protein vinexin alpha regulates the phosphorylation and activity of estrogen receptor alpha
RL J. Biol. Chem. 279:9255-63 (2004).
RN [28]; RE0039795.
RX PUBMED: 14702340.
RA Masuyama H., Hiramatsu Y.
RT Involvement of suppressor for Gal 1 in the ubiquitin/proteasome-mediated degradation of estrogen receptors
RL J. Biol. Chem. 279:12020-6 (2004).
RN [29]; RE0039945.
RX PUBMED: 9841885.
RA Song M. R., Lee S. K., Seo Y. W., Choi H. S., Lee J. W., Lee M. O.
RT Differential modulation of transcriptional activity of oestrogen receptors by direct protein-protein interactions with retinoid receptors
RL Biochem. J. 336:711-7 (1998).
RN [30]; RE0041011.
RX PUBMED: 11061546.
RA Chiang C. H., Cheng K. W., Igarashi S., Nathwani P. S., Leung P. C.
RT Hormonal regulation of estrogen receptor alpha and beta gene expression in human granulosa-luteal cells in vitro
RL J. Clin. Endocrinol. Metab. 85:3828-39 (2000).
RN [31]; RE0041229.
RX PUBMED: 11867769.
RA Kang Y. K., Guermah M., Yuan C. X., Roeder R. G.
RT The TRAP/Mediator coactivator complex interacts directly with estrogen receptors alpha and beta through the TRAP220 subunit and directly enhances estrogen receptor function in vitro
RL Proc. Natl. Acad. Sci. USA 99:2642-7 (2002).
RN [32]; RE0041230.
RX PUBMED: 10747867.
RA Kobayashi Y., Kitamoto T., Masuhiro Y., Watanabe M., Kase T., Metzger D., Yanagisawa J., Kato S.
RT p300 mediates functional synergism between AF-1 and AF-2 of estrogen receptor alpha and beta by interacting directly with the N-terminal A/B domains
RL J. Biol. Chem. 275:15645-51 (2000).
RN [33]; RE0041234.
RX PUBMED: 14739282.
RA Melvin V. S., Harrell C., Adelman J. S., Kraus W. L., Churchill M., Edwards D. P.
RT The role of the C-terminal extension (CTE) of the estrogen receptor alpha and beta DNA binding domain in DNA binding and interaction with HMGB
RL J. Biol. Chem. 279:14763-71 (2004).
RN [34]; RE0041807.
RX PUBMED: 11113208.
RA Sauve F., McBroom L. D., Gallant J., Moraitis A. N., Labrie F., Giguere V.
RT CIA, a novel estrogen receptor coactivator with a bifunctional nuclear receptor interacting determinant
RL Mol. Cell. Biol. 21:343-53 (2001).
RN [35]; RE0041862.
RX PUBMED: 11555647.
RA Matsuda T., Yamamoto T., Muraguchi A., Saatcioglu F.
RT Cross-talk between transforming growth factor-beta and estrogen receptor signaling through Smad3
RL J. Biol. Chem. 276:42908-14 (2001).
RN [36]; RE0042014.
RX PUBMED: 12943696.
RA Deblois G., Giguere V.
RT Ligand-independent coactivation of ERalpha AF-1 by steroid receptor RNA activator (SRA) via MAPK activation
RL J. Steroid Biochem. Mol. Biol. 85:123-31 (2003).
RN [37]; RE0042097.
RX PUBMED: 12213896.
RA Gargett C. E., Zaitseva M., Bucak K., Chu S., Fuller P. J., Rogers P. A.
RT 17Beta-estradiol up-regulates vascular endothelial growth factor receptor-2 expression in human myometrial microvascular endothelial cells: role of estrogen receptor-alpha and -beta
RL J. Clin. Endocrinol. Metab. 87:4341-9 (2002).
RN [38]; RE0042105.
RX PUBMED: 11156416.
RA Ali S. H., O'Donnell A. L., Balu D., Pohl M. B., Seyler M. J., Mohamed S., Mousa S., Dandona P.
RT Estrogen receptor-alpha in the inhibition of cancer growth and angiogenesis
RL Cancer Res. 60:7094-8 (2000).
RN [39]; RE0042106.
RX PUBMED: 11529880.
RA Ali S. H., O'Donnell A. L., Balu D., Pohl M. B., Seyler M. J., Mohamed S., Mousa S., Dandona P.
RT High levels of oestrogen receptor-alpha in tumorigenesis: inhibition of cell growth and angiogenic factors
RL Cell Prolif. 34:223-31 (2001).
RN [40]; RE0042119.
RX PUBMED: 11145749.
RA Lei Z. M., Mishra S., Zou W., Xu B., Foltz M., Li X., Rao C. V.
RT Targeted Disruption of Luteinizing Hormone/Human Chorionic Gonadotropin Receptor Gene
RL Mol. Endocrinol. 15:184-200 (2001).
RN [41]; RE0042285.
RX PUBMED: 12624116.
RA Couse J. F., Yates M. M., Walker V. R., Korach K. S.
RT Characterization of the hypothalamic-pituitary-gonadal axis in estrogen receptor (ER) Null mice reveals hypergonadism and endocrine sex reversal in females lacking ERalpha but not ERbeta
RL Mol. Endocrinol. 17:1039-53 (2003).
RN [42]; RE0042313.
RX PUBMED: 10619353.
RA Klinge C. M.
RT Role of estrogen receptor ligand and estrogen response element sequence on interaction with chicken ovalbumin upstream promoter transcription factor (COUP-TF)
RL J. Steroid Biochem. Mol. Biol. 71:1-19 (1999).
RN [43]; RE0042365.
RX PUBMED: 11700319.
RA Walters M. R., Dutertre M., Smith C. L.
RT SKF-82958 is a subtype-selective estrogen receptor-alpha (ERalpha ) agonist that induces functional interactions between ERalpha and AP-1
RL J. Biol. Chem. 277:1669-79 (2002).
RN [44]; RE0042378.
RX PUBMED: 14722092.
RA Matsuda S., Harries J. C., Viskaduraki M., Troke P. J., Kindle K. B., Ryan C., Heery D. M.
RT A Conserved alpha-helical motif mediates the binding of diverse nuclear proteins to the SRC1 interaction domain of CBP
RL J. Biol. Chem. 279:14055-64 (2004).
RN [45]; RE0042443.
RX PUBMED: 12782587.
RA Kelley K. M., Rowan B. G., Ratnam M.
RT Modulation of the folate receptor alpha gene by the estrogen receptor: mechanism and implications in tumor targeting
RL Cancer Res. 63:2820-8 (2003).
RN [46]; RE0042619.
RX PUBMED: 11432835.
RA Clark D. E., Poteet-Smith C. E., Smith J. A., Lannigan D. A.
RT Rsk2 allosterically activates estrogen receptor alpha by docking to the hormone-binding domain
RL EMBO J. 20:3484-94 (2001).
RN [47]; RE0042804.
RX PUBMED: 10454579.
RA Kim H. J., Yi J. Y., Sung H. S., Moore D. D., Jhun B. H., Lee Y. C., Lee J. W.
RT Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation
RL Mol. Cell. Biol. 19:6323-32 (1999).
RN [48]; RE0043186.
RX PUBMED: 11698654.
RA Zhou Q., Clarke L., Nie R., Carnes K., Lai L. W., Lien Y. H., Verkman A., Lubahn D., Fisher J. S., Katzenellenbogen B. S., Hess R. A.
RT Estrogen action and male fertility: roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function
RL Proc. Natl. Acad. Sci. USA 98:14132-7 (2001).
RN [49]; RE0044304.
RX PUBMED: 11641386.
RA Geary G. G., McNeill A. M., Ospina J. A., Krause D. N., Korach K. S., Duckles S. P.
RT Selected contribution: cerebrovascular nos and cyclooxygenase are unaffected by estrogen in mice lacking estrogen receptor-alpha
RL J. Appl. Physiol. 91:2391-9 (2001).
RN [50]; RE0044667.
RX PUBMED: 15289619.
RA Shao W., Keeton E. K., McDonnell D. P., Brown M.
RT Coactivator AIB1 links estrogen receptor transcriptional activity and stability
RL Proc. Natl. Acad. Sci. USA 101:11599-604 (2004).
RN [51]; RE0044750.
RX PUBMED: 12586845.
RA Hall J. M., Korach K. S.
RT Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells
RL Mol. Endocrinol. 17:792-803 (2003).
RN [52]; RE0044905.
RX PUBMED: 11773441.
RA Lee S. R., Ramos S. M., Ko A., Masiello D., Swanson K. D., Lu M. L., Balk S. P.
RT AR and ER interaction with a p21-activated kinase (PAK6)
RL Mol. Endocrinol. 16:85-99 (2002).
RN [53]; RE0045164.
RX PUBMED: 15342491.
RA Aiyar S. E., Sun J. L., Blair A. L., Moskaluk C. A., Lu Y. Z., Ye Q. N., Yamaguchi Y., Mukherjee A., Ren D. M., Handa H., Li R.
RT Attenuation of estrogen receptor alpha-mediated transcription through estrogen-stimulated recruitment of a negative elongation factor
RL Genes Dev. 18:2134-46 (2004).
RN [54]; RE0045474.
RX PUBMED: 11136725.
RA Prevot D., Morel A. P., Voeltzel T., Rostan M. C., Rimokh R., Magaud J. P., Corbo L.
RT Relationships of the Antiproliferative Proteins BTG1 and BTG2 with CAF1, the Human Homolog of a Component of the Yeast CCR4 Transcriptional Complex. INVOLVEMENT IN ESTROGEN RECEPTOR alpha SIGNALING PATHWAY
RL J. Biol. Chem. 276:9640-8 (2001).
RN [55]; RE0045658.
RX PUBMED: 15066997.
RA Townson S. M., Kang K., Lee A. V., Oesterreich S.
RT Structure-function analysis of the estrogen receptor alpha corepressor scaffold attachment factor-B1: identification of a potent transcriptional repression domain
RL J. Biol. Chem. 279:26074-81 (2004).
RN [56]; RE0045717.
RX PUBMED: 11784056.
RA Kurita T., Cooke P. S., Cunha G. R.
RT Epithelial-stromal tissue interaction in paramesonephric (Mullerian) epithelial differentiation
RL Dev. Biol. 240:194-211 (2001).
RN [57]; RE0045817.
RX PUBMED: 10894150.
RA Platet N., Cunat S., Chalbos D., Rochefort H., Garcia M.
RT Unliganded and liganded estrogen receptors protect against cancer invasion via different mechanisms
RL Mol. Endocrinol. 14:999-1009 (2000).
RN [58]; RE0045857.
RX PUBMED: 12897156.
RA Kinyamu H. K., Archer T. K.
RT Estrogen receptor-dependent proteasomal degradation of the glucocorticoid receptor is coupled to an increase in mdm2 protein expression
RL Mol. Cell. Biol. 23:5867-81 (2003).
RN [59]; RE0046075.
RX PUBMED: 11279242.
RA Wu X., Li H., Chen J. D.
RT The human homologue of the yeast DNA repair and TFIIH regulator MMS19 is an AF-1-specific coactivator of estrogen receptor
RL J. Biol. Chem. 276:23962-8 (2001).
RN [60]; RE0046121.
RX PUBMED: 11139588.
RA Campbell R. A., Bhat-Nakshatri P., Patel N. M., Constantinidou D., Ali S., Nakshatri H.
RT Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance
RL J. Biol. Chem. 276:9817-24 (2001).
RN [61]; RE0046191.
RX PUBMED: 12586776.
RA Doisneau-Sixou S. F., Cestac P., Chouini S., Carroll J. S., Hamilton A. D., Sebti S. M., Poirot M., Balaguer P., Faye J. C., Sutherland R. L., Favre G.
RT Contrasting effects of prenyltransferase inhibitors on estrogen-dependent cell cycle progression and estrogen receptor-mediated transcriptional activity in MCF-7 cells
RL Endocrinology 144:989-98 (2003).
RN [62]; RE0046253.
RX PUBMED: 11997270.
RA Herrington D. M., Howard T. D., Brosnihan K. B., McDonnell D. P., Li X., Hawkins G. A., Reboussin D. M., Xu J., Zheng S. L., Meyers D. A., Bleecker E. R.
RT Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein
RL Circulation 105:1879-82 (2002).
RN [63]; RE0046545.
RX PUBMED: 11358960.
RA Chan S. W., Hong W.
RT Retinoblastoma-binding protein 2 (Rbp2) potentiates nuclear hormone receptor-mediated transcription
RL J. Biol. Chem. 276:28402-12 (2001).
RN [64]; RE0046714.
RX PUBMED: 10748020.
RA Tcherepanova I., Puigserver P., Norris J. D., Spiegelman B. M., McDonnell D. P.
RT Modulation of estrogen receptor-alpha transcriptional activity by the coactivator PGC-1
RL J. Biol. Chem. 275:16302-8 (2000).
RN [65]; RE0046748.
RX PUBMED: 12754377.
RA Brunnberg S., Pettersson K., Rydin E., Matthews J., Hanberg A., Pongratz I.
RT The basic helix-loop-helix-PAS protein ARNT functions as a potent coactivator of estrogen receptor-dependent transcription
RL Proc. Natl. Acad. Sci. USA 100:6517-22 (2003).
RN [66]; RE0046789.
RX PUBMED: 11564893.
RA Teo A. K., Oh H. K., Ali R. B., Li B. F.
RT The modified human dna repair enzyme o(6)-methylguanine-dna methyltransferase is a negative regulator of estrogen receptor-mediated transcription upon alkylation dna damage
RL Mol. Cell. Biol. 21:7105-14 (2001).
RN [67]; RE0047243.
RX PUBMED: 15047147.
RA Bu H., Kashireddy P., Chang J., Zhu Y. T., Zhang Z., Zheng W., Rao S. M., Zhu Y. J.
RT ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor
RL Biochem. Biophys. Res. Commun. 317:54-9 (2004).
RN [68]; RE0047326.
RX PUBMED: 15538384.
RA Tateishi Y., Kawabe Y., Chiba T., Murata S., Ichikawa K., Murayama A., Tanaka K., Baba T., Kato S., Yanagisawa J.
RT Ligand-dependent switching of ubiquitin-proteasome pathways for estrogen receptor.
RL EMBO J. 23:4813-4823 (2004).
RN [69]; RE0047547.
RX PUBMED: 11146623.
RA Mazumdar A., Wang R. A., Mishra S. K., Adam L., Bagheri-Yarmand R., Mandal M., Vadlamudi R. K., Kumar R.
RT Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor.
RL Nat. Cell Biol. 3:30-37 (2001).
RN [70]; RE0047561.
RX PUBMED: 15655247.
RA Bourguignon L. Y., Gilad E., Rothman K., Peyrollier K.
RT Hyaluronan-CD44 interaction with IQGAP1 promotes Cdc42 and ERK signaling, leading to actin binding, Elk-1/estrogen receptor transcriptional activation, and ovarian cancer progression.
RL J. Biol. Chem. 280:11961-11972 (2005).
RN [71]; RE0049501.
RX PUBMED: 16087727.
RA Reizner N., Maor S., Sarfstein R., Abramovitch S., Welshons W. V., Curran E. M., Lee A. V., Werner H.
RT The WT1 Wilms' tumor suppressor gene product interacts with estrogen receptor-alpha and regulates IGF-I receptor gene transcription in breast cancer cells.
RL J. Mol. Endocrinol. 35:135-144 (2005).
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RT P21-activated kinase 1 regulation of estrogen receptor-alpha activation involves serine 305 activation linked with serine 118 phosphorylation.
RL Cancer Res. 66:1694-1701 (2006).
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RT Estrogen receptor alpha is a putative substrate for the BRCA1 ubiquitin ligase.
RL Proc. Natl. Acad. Sci. USA 104:5794-5799 (2007).
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RT PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex.
RL Biochem. Biophys. Res. Commun. 343:535-43 (2006).
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RT CCPG, a Novel Constitutive Coactivator of PPAR{gamma} that Promotes Adipogenesis.
RL Mol. Endocrinol. 21:2320-2333 (2007).
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RT Direct interaction between BRCA1 and the estrogen receptor regulates vascular endothelial growth factor (VEGF) transcription and secretion in breast cancer cells.
RL Oncogene 21:7730-7739 (2002).
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RT Structural determinants of the BRCA1 : estrogen receptor interaction.
RL Oncogene 24:1831-1846 (2005).
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RA Crowe D. L., Lee M. K.
RT New role for nuclear hormone receptors and coactivators in regulation of BRCA1-mediated DNA repair in breast cancer cell lines.
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RT The Src kinase pathway promotes tamoxifen agonist action in Ishikawa endometrial cells through phosphorylation-dependent stabilization of estrogen receptor (alpha) promoter interaction and elevated steroid receptor coactivator 1 activity.
RL Mol. Endocrinol. 19:732-748 (2005).
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RA Likhite V. S., Stossi F., Kim K., Katzenellenbogen B. S., Katzenellenbogen J. A.
RT Kinase-specific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity.
RL Mol. Endocrinol. 20:3120-3132 (2006).
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RA Joel P. B., Smith J., Sturgill T. W., Fisher T. L., Blenis J., Lannigan D. A.
RT pp90rsk1 regulates estrogen receptor-mediated transcription through phosphorylation of Ser-167.
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RA Cui Y., Zhang M., Pestell R., Curran E. M., Welshons W. V., Fuqua S. A.
RT Phosphorylation of estrogen receptor alpha blocks its acetylation and regulates estrogen sensitivity.
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RT Overexpression of histone deacetylase HDAC1 modulates breast cancer progression by negative regulation of estrogen receptor alpha.
RL Int. J. Cancer 107:353-358 (2003).
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RA Zou J. X., Revenko A. S., Li L. B., Gemo A. T., Chen H. W.
RT ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERalpha, is required for coregulator occupancy and chromatin modification.
RL Proc. Natl. Acad. Sci. USA 104:18067-18072 (2007).
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RA Nettles K. W., Gil G., Nowak J., Metivier R., Sharma V. B., Greene G. L.
RT CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor.
RL Mol. Endocrinol. 22:263-272 (2008).
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RA Li Y., Sun L., Zhang Y., Wang D., Wang F., Liang J., Gui B., Shang Y.
RT The histone modifications governing TFF1 transcription mediated by estrogen receptor.
RL J. Biol. Chem. 286:13925-13936 (2011).
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