AC T09095
XX
ID T09095
XX
DT 10.03.2005 (created); nvo.
DT 09.10.2014 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA SREBP-1
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T09637 ER-alpha; Mammalia.
IN T16015 ER-beta; Mammalia.
IN T08326 Sp1; Mammalia.
XX
MX M00220 V$SREBP1_01.
MX M00221 V$SREBP1_02.
MX M01173 V$SREBP1_Q5.
MX M00749 V$SREBP1_Q6.
MX M04632 V$SREBP1_Q6_01.
MX M00776 V$SREBP_Q3.
MX M01168 V$SREBP_Q6.
XX
BS R37054.
BS R22482.
BS R20650.
BS R20651.
BS R26039.
BS R22321.
BS R22765.
BS R22767.
BS R22768.
BS R27725.
BS R30362.
BS R28167.
BS R28168.
BS R19452.
BS R22438.
BS R22439.
BS R22374.
BS R22375.
BS R22378.
BS R22379.
BS R22380.
XX
DR TRANSPATH: MO000046468.
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RN [1]; RE0016408.
RX PUBMED: 10777536.
RA Sato R., Okamoto A., Inoue J., Miyamoto W., Sakai Y., Emoto N., Shimano H., Maeda M.
RT Transcriptional regulation of the ATP citrate-lyase gene by sterol regulatory element-binding proteins.
RL J. Biol. Chem. 275:12497-12502 (2000).
RN [2]; RE0029395.
RX PUBMED: 10627507.
RA Kotzka J., Muller-Wieland D., Roth G., Kremer L., Munck M., Schurmann S., Knebel B., Krone W.
RT Sterol regulatory element binding proteins (SREBP)-1a and SREBP-2 are linked to the MAP-kinase cascade.
RL J. Lipid Res. 41:99-108 (2000).
RN [3]; RE0030242.
RX PUBMED: 12562867.
RA Kapoor G. S., Golden C., Atkins B., Mehta K. D.
RT pp90RSK- and protein kinase C-dependent pathway regulates p42/44MAPK-induced LDL receptor transcription in HepG2 cells.
RL J. Lipid Res. 44:584-93 (2003).
RN [4]; RE0031600.
RX PUBMED: 14748724.
RA Tarling E., Salter A., Bennett A.
RT Transcriptional regulation of human SREBP-1c (sterol-regulatory-element-binding protein-1c): a key regulator of lipogenesis.
RL Biochem. Soc. Trans. 32:107-9 (2004).
RN [5]; RE0031601.
RX PUBMED: 14722127.
RA Yamamoto T., Shimano H., Nakagawa Y., Ide T., Yahagi N., Matsuzaka T., Nakakuki M., Takahashi A., Suzuki H., Sone H., Toyoshima H., Sato R., Yamada N.
RT SREBP-1 interacts with hepatocyte nuclear factor-4 alpha and interferes with PGC-1 recruitment to suppress hepatic gluconeogenic genes.
RL J. Biol. Chem. 279:12027-35 (2004).
RN [6]; RE0037686.
RX PUBMED: 11279217.
RA Kim J. H., Lee J. N., Paik Y. K.
RT Cholesterol biosynthesis from lanosterol. A concerted role for Sp1 and NF-Y-binding sites for sterol-mediated regulation of rat 7-dehydrocholesterol reductase gene expression
RL J. Biol. Chem. 276:18153-60 (2001).
RN [7]; RE0038603.
RX PUBMED: 10579331.
RA Lopez D., McLean M. P.
RT Sterol regulatory element-binding protein-1a binds to cis elements in the promoter of the rat high density lipoprotein receptor SR-BI gene
RL Endocrinology 140:5669-5681 (1999).
RN [8]; RE0038613.
RX PUBMED: 12021179.
RA Lopez D., Sanchez M. D., Shea-Eaton W., McLean M. P.
RT Estrogen activates the high-density lipoprotein receptor gene via binding to estrogen response elements and interaction with sterol regulatory element binding protein-1A
RL Endocrinology 143:2155-68 (2002).
RN [9]; RE0040088.
RX PUBMED: 12624180.
RA Yabe D., Komuro R., Liang G., Goldstein J. L., Brown M. S.
RT Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis
RL Proc. Natl. Acad. Sci. USA 100:3155-60 (2003).
RN [10]; RE0040093.
RX PUBMED: 15085196.
RA Engelking L. J., Kuriyama H., Hammer R. E., Horton J. D., Brown M. S., Goldstein J. L., Liang G.
RT Overexpression of Insig-1 in the livers of transgenic mice inhibits SREBP processing and reduces insulin-stimulated lipogenesis
RL J. Clin. Invest. 113:1168-75 (2004).
RN [11]; RE0040556.
RX PUBMED: 12427732.
RA Borchert A., Savaskan N. E., Kuhn H.
RT Regulation of expression of the phospholipid hydroperoxide/sperm nucleus glutathione peroxidase gene. Tissue-specific expression pattern and identification of functional cis- and trans-regulatory elements
RL J. Biol. Chem. 278:2571-80 (2003).
RN [12]; RE0043227.
RX PUBMED: 12923220.
RA Shechter I., Dai P., Huo L., Guan G.
RT IDH1 gene transcription is sterol regulated and activated by SREBP-1a and SREBP-2 in human hepatoma HepG2 cells: evidence that IDH1 may regulate lipogenesis in hepatic cells
RL J. Lipid Res. 44:2169-80 (2003).
RN [13]; RE0043449.
RX PUBMED: 12640139.
RA Giandomenico V., Simonsson M., Gronroos E., Ericsson J.
RT Coactivator-dependent acetylation stabilizes members of the SREBP family of transcription factors
RL Mol. Cell. Biol. 23:2587-99 (2003).
RN [14]; RE0045615.
RX PUBMED: 11435428.
RA Ikeda Y., Yamamoto J., Okamura M., Fujino T., Takahashi S., Takeuchi K., Osborne T. F., Yamamoto T. T., Ito S., Sakai J.
RT Transcriptional regulation of the murine acetyl-CoA synthetase 1 gene through multiple clustered binding sites for sterol regulatory element-binding proteins and a single neighboring site for Sp1
RL J. Biol. Chem. 276:34259-69 (2001).
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