AC T02187
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ID T02187
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DT 05.06.1997 (created); hiwi.
DT 11.03.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA MAT1
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SY MAT1; p36; TFIIH-MAT1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G003990 MNAT1; HGNC: MNAT1.
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SF part of the cyclin-dependent kinase-activating kinase (CAK) subcomplex of TFIIH [1] [2];
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FF stimulates the kinase activity of the CAK complex, but is dispensable [2];
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IN T02184 cyclinH; human, Homo sapiens.
IN T00261 ER-alpha; human, Homo sapiens.
IN T09637 ER-alpha; Mammalia.
IN T02186 MO15; human, Homo sapiens.
IN T10759 MTA-1; human, Homo sapiens.
IN T11165 NKX3A; human, Homo sapiens.
IN T00719 NR1B1-isoform1; human, Homo sapiens.
IN T00647 Oct-2; human, Homo sapiens.
IN T05465 OTF3P1; human, Homo sapiens.
IN T00671 p53; human, Homo sapiens.
IN T00641 POU2F1-isoform1; human, Homo sapiens.
IN T01330 RAR-gamma1; human, Homo sapiens.
IN T00759 Sp1; human, Homo sapiens.
IN T02188 TFIIH-p34; human, Homo sapiens.
IN T02183 TFIIH-p62; human, Homo sapiens.
IN T02182 TFIIH-p80; human, Homo sapiens.
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DR TRANSPATH: MO000023481.
DR UniProtKB: P51948;
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RN [1]; RE0005770.
RX PUBMED: 8692841.
RA Reardon J. T., Ge H., Gibbs E., Sancar A., Hurwitz J., Pan Z.-Q.
RT Isolation and characterization of two human transcription factor IIH(TFIIH)-related complexes: ERCC2/CAK and TFIIH*
RL Proc. Natl. Acad. Sci. USA 93:6482-6487 (1996).
RN [2]; RE0005786.
RX PUBMED: 8617234.
RA Adamczewski J. P., Rossignol M., Tassan J.-P., Nigg E. A., Moncollin V., Egly J.-M.
RT MAT1, cdk7 and cyclin H form a kinase complex which is UV light-sensitive upon association with TFIIH
RL EMBO J. 15:1877-1884 (1996).
RN [3]; RE0035947.
RX PUBMED: 12527756.
RA Talukder A. H., Mishra S. K., Mandal M., Balasenthil S., Mehta S., Sahin A. A., Barnes C. J., Kumar R.
RT MTA1 interacts with MAT1, a cyclin-dependent kinase-activating kinase complex ring finger factor, and regulates estrogen receptor transactivation functions.
RL J. Biol. Chem. 278:11676-11685 (2003).
RN [4]; RE0023310.
RX PUBMED: 10748061.
RA Bastien J., Adam-Stitah S., Riedl T., Egly J. M., Chambon P., Rochette-Egly C.
RT TFIIH interacts with the retinoic acid receptor gamma and phosphorylates its AF-1-activating domain through cdk7.
RL J. Biol. Chem. 275:21896-21904 (2000).
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