AC T01330
XX
ID T01330
XX
DT 25.10.1994 (created); ewi.
DT 28.09.2007 (updated); bch.
CO Copyright (C), QIAGEN.
XX
FA RAR-gamma1
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SY RAR-gamma1; retinoic acid receptor gamma1.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G000377 RARG; HGNC: rarg.
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CL C0002; CC (rec); 2.1.2.1.3.1.
XX
SZ 454 AA; 50.3 kDa (cDNA) (calc.).
XX
SQ MATNKERLFAAGALGPGSGYPGAGFPFAFPGALRGSPPFEMLSPSFRGLGQPDLPKEMAS
SQ LSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQK
SQ NMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDRNKKKKEVKEEGSPDSY
SQ ELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRVQLDLGLWDKFSELATKCIIK
SQ IVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNRTQMH
SQ NAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEPLLEA
SQ LRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREMLENPE
SQ MFEDDSSQPGPHPNASSEDEVPGGQGKGGLKSPA
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SC Swiss-Prot#P13631-1
XX
FT 87 158 
SM00399; c4gold.
FT 87 162 
PS51030; NUCLEAR_REC_DBD_2.
FT 88 163 
PF00105; Zinc finger, C4 type (two domains).
FT 232 390 
SM00430; holi.
FT 235 415 
PF00104; Ligand-binding domain of nuclear hormon.
FT 371 393 
helix 10 [9].
FT 398 417 
helix 11 [9].
XX
FF negative control of AP-1 responsive genes;
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IN T02184 cyclinH; human, Homo sapiens.
IN T02187 MAT1; human, Homo sapiens.
IN T02186 MO15; human, Homo sapiens.
IN T08641 NCOR1-isoform1; mouse, Mus musculus.
IN T01427 p300; human, Homo sapiens.
IN T01331 RXR-alpha; mouse, Mus musculus.
IN T01345 RXR-alpha; human, Homo sapiens.
IN T01359 RXR-alpha; clawed frog, Xenopus laevis.
IN T08348 RXR-alpha; mouse, Mus musculus.
IN T01332 RXR-beta; mouse, Mus musculus.
IN T01334 RXR-beta; human, Homo sapiens.
IN T01349 RXR-beta; rat, Rattus norvegicus.
IN T01333 RXR-gamma; mouse, Mus musculus.
IN T01360 RXR-gamma; clawed frog, Xenopus laevis.
IN T04639 SRC-1; mouse, Mus musculus.
IN T02183 TFIIH-p62; human, Homo sapiens.
IN T02181 TFIIH-p90; human, Homo sapiens.
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MX M07280 V$NR1NR2_Q3.
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BS R20826.
BS R04075.
BS R03962.
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DR TRANSPATH: MO000025589.
DR EMBL: M24857;
DR EMBL: M38258;
DR EMBL: M57707;
DR UniProtKB: P13631-1;
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RN [1]; RE0000265.
RX PUBMED: 1310259.
RA Leid M., Kastner P., Lyons R., Nakshatri H., Saunders M., Zacharewski T., Chen J.-Y., Staub A., Garnier J.-M., Mader S., Chambon P.
RT Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently
RL Cell 68:377-395 (1992).
RN [2]; RE0000554.
RX PUBMED: 2176152.
RA Nicholson R. C., Mader S., Nagpal S., Leid M., Rochette-Egly C., Chambon P.
RT Negative regulation of the rat stromelysin gene promoter by retinoic acid is mediated by an AP1 binding site
RL EMBO J. 9:4443-4454 (1990).
RN [3]; RE0001917.
RX PUBMED: 1310350.
RA Zhang X. K., Hoffmann B., Tran P. B.-V., Graupner G., Pfahl M.
RT Retinoid X receptor is an auxiliary protein for thyroid hormone and retinoic acid receptors
RL Nature 355:441-446 (1992).
RN [4]; RE0002566.
RX PUBMED: 1648728.
RA Schuele R., Rangarajan P., Yang N., Kliewer S., Ransone L. J., Bolado J., Verma I. M., Evans R. M.
RT Retinoic acid is a negative regulator of AP-1-responsive genes
RL Proc. Natl. Acad. Sci. USA 88:6092-6096 (1991).
RN [5]; RE0002567.
RX PUBMED: 2546152.
RA Krust A., Kastner P., Petkovich M., Zelent A., Chambon P.
RT A third human retinoic acid receptor, hRAR-gamma
RL Proc. Natl. Acad. Sci. USA 86:5310-5314 (1989).
RN [6]; RE0016813.
RX PUBMED: 10336495.
RA Dowell P., Ishmael J. E., Avram D., Peterson V. J., Nevrivy D. J., Leid M.
RT Identification of nuclear receptor corepressor as a peroxisome proliferator-activated receptor alpha interacting protein
RL J. Biol. Chem. 274:15901-15907 (1999).
RN [7]; RE0040875.
RX PUBMED: 9407140.
RA Dowell P., Ishmael J. E., Avram D., Peterson V. J., Nevrivy D. J., Leid M.
RT p300 functions as a coactivator for the peroxisome proliferator-activated receptor alpha
RL J. Biol. Chem. 272:33435-43 (1997).
RN [8]; RE0047743.
RX PUBMED: 15610520.
RA Flores A. M., Li L., Aneskievich B. J.
RT Isolation and functional analysis of a keratinocyte-derived, ligand-regulated nuclear receptor comodulator.
RL J. Invest. Dermatol 123:1092-1101 (2004).
RN [9]; RE0049022.
RX PUBMED: 9660764.
RA Chinpaisal C., Lee C. H., Wei L. N.
RT Mechanisms of the mouse orphan nuclear receptor TR2-11-mediated gene suppression.
RL J. Biol. Chem. 273:18077-18085 (1998).
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