TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T06121 XX ID T06121 XX DT 27.08.2004 (created); elf. DT 31.03.2015 (updated); msr. CO Copyright (C), QIAGEN. XX FA ERR3 XX SY ERR gamma; ESRRG; estrogen receptor related protein 3; estrogen-related receptor gamma; NR3B3. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002761 ESRRG; HGNC: ESRRG. XX CL C0002; CC (rec); XX SF The ERR3 T06121 is highly alternatively spliced at the 5'end to ERR3-1 T04648 and ERR3-2 T04645 [1]; XX CP high: brain, kidney, pancreas, placenta, heart, skeletal muscle, [1]; weak: prostate, spleen, testis, small intestine [1] [1]. XX IN T02776 DAX1; human, Homo sapiens. IN T02765 ERR1; human, Homo sapiens. IN T04922 Prox-1; human, Homo sapiens. IN T04632 SRC-1; human, Homo sapiens. IN T21552 SRC-1; Mammalia. XX MX M02000 V$ERR3_Q2. MX M02094 V$ERR3_Q2_01. MX M04462 V$ESRRG_03. XX BS R15510. BS R35017. BS R66963. BS R66964. BS R66966. BS R72987. BS R72977. BS R27214. BS R35037. XX DR TRANSPATH: MO000028478. DR EMBL: AF094518; AF094518. DR UniProtKB: P62508; XX RN [1]; RE0016531. RX PUBMED: 10707956. RA Heard D. J., Norby P. L., Holloway J., Vissing H. RT Human ERRgamma, a third member of the estrogen receptor-related receptor (ERR) subfamily of orphan nuclear receptors: tissue-specific isoforms are expressed during development and in the adult RL Mol. Endocrinol. 14:382-392 (2000). RN [2]; RE0047206. RX PUBMED: 11447273. RA Coward P., Lee D., Hull M. V., Lehmann J. M. RT 4-Hydroxytamoxifen binds to and deactivates the estrogen-related receptor gamma RL Proc. Natl. Acad. Sci. USA 98:8880-4 (2001). RN [3]; RE0047209. RX PUBMED: 11864604. RA Greschik H., Wurtz J. M., Sanglier S., Bourguet W., van Dorsselaer A., Moras D., Renaud J. P. RT Structural and functional evidence for ligand-independent transcriptional activation by the estrogen-related receptor 3 RL Mol. Cell 9:303-13 (2002). RN [4]; RE0054989. RX PUBMED: 15604093. RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M. RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. RL Mol. Cell. Proteomics 4:205-213 (2005). RN [5]; RE0067936. RX PUBMED: 19019082. RA Pridgeon J. W., Webber E. A., Sha D., Li L., Chin L. S. RT Proteomic analysis reveals Hrs ubiquitin-interacting motif-mediated ubiquitin signaling in multiple cellular processes. RL FEBS J. 276:118-131 (2009). XX //