TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T04922 XX ID T04922 XX DT 26.11.2001 (created); rge. DT 11.01.2016 (updated); mkl. CO Copyright (C), QIAGEN. XX FA Prox-1 XX SY PROX-1; prox1. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G005717 PROX1; HGNC: PROX1. XX CL C0006; homeo; XX FF Six.3 and Prox-1 act antagonistically on regulation of CRYGD/e/f promotors [2]; XX IN T10523 c-Ets-2; human, Homo sapiens. IN T06040 CtBP2; human, Homo sapiens. IN T02765 ERR1; human, Homo sapiens. IN T06121 ERR3; human, Homo sapiens. IN T03828 HNF-4alpha; human, Homo sapiens. IN T02770 LRH-1; human, Homo sapiens. IN T00513 MR; human, Homo sapiens. IN T02745 PPARdelta; human, Homo sapiens. IN T09566 RORalpha; human, Homo sapiens. IN T10378 Smad3; human, Homo sapiens. XX BS R24643. BS R62126. BS R62129. BS R73760. BS R66533. XX DR TRANSPATH: MO000028703. DR TRANSCOMPEL: C00564. DR UniProtKB: Q92786; XX RN [1]; RE0017255. RX PUBMED: 8812486. RA Zinovieva R. D., Duncan M. K., Johnson T. R., Torres R., Polymeropoulos M. H., Tomarev S. I. RT Structure and chromosomal localization of the human homeobox gene Prox 1 RL Genomics 35:517-522 (1996). RN [2]; RE0023150. RX PUBMED: 11139622. RA Lengler J., Krausz E., Tomarev S., Prescott A., Quinlan R. A., Graw J. RT Antagonistic action of Six3 and Prox1 at the gamma-crystallin promoter. RL Nucleic Acids Res. 29:515-526 (2001). RN [3]; RE0053152. RX PUBMED: 15205472. RA Qin J., Gao D. M., Jiang Q. F., Zhou Q., Kong Y. Y., Wang Y., Xie Y. H. RT Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene. RL Mol. Endocrinol. 18:2424-2439 (2004). RN [4]; RE0053638. RX PUBMED: 16488887. RA Song K. H., Li T., Chiang J. Y. RT A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene. RL J. Biol. Chem. 281:10081-10088 (2006). RN [5]; RE0054989. RX PUBMED: 15604093. RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M. RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. RL Mol. Cell. Proteomics 4:205-213 (2005). XX //