AC T04922
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ID T04922
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DT 26.11.2001 (created); rge.
DT 11.01.2016 (updated); mkl.
CO Copyright (C), QIAGEN.
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FA Prox-1
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SY PROX-1; prox1.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G005717 PROX1; HGNC: PROX1.
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CL C0006; homeo; 3.1.7.0.1.
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FF Six.3 and Prox-1 act antagonistically on regulation of CRYGD/e/f promotors [2];
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IN T10523 c-Ets-2; human, Homo sapiens.
IN T06040 CtBP2; human, Homo sapiens.
IN T02765 ERR1; human, Homo sapiens.
IN T06121 ERR3; human, Homo sapiens.
IN T03828 HNF-4alpha; human, Homo sapiens.
IN T02770 LRH-1; human, Homo sapiens.
IN T00513 MR; human, Homo sapiens.
IN T02745 PPARdelta; human, Homo sapiens.
IN T09566 RORalpha; human, Homo sapiens.
IN T10378 Smad3; human, Homo sapiens.
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BS R24643.
BS R62126.
BS R62129.
BS R73760.
BS R66533.
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DR TRANSPATH: MO000028703.
DR TRANSCOMPEL: C00564.
DR UniProtKB: Q92786;
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RN [1]; RE0017255.
RX PUBMED: 8812486.
RA Zinovieva R. D., Duncan M. K., Johnson T. R., Torres R., Polymeropoulos M. H., Tomarev S. I.
RT Structure and chromosomal localization of the human homeobox gene Prox 1
RL Genomics 35:517-522 (1996).
RN [2]; RE0023150.
RX PUBMED: 11139622.
RA Lengler J., Krausz E., Tomarev S., Prescott A., Quinlan R. A., Graw J.
RT Antagonistic action of Six3 and Prox1 at the gamma-crystallin promoter.
RL Nucleic Acids Res. 29:515-526 (2001).
RN [3]; RE0053152.
RX PUBMED: 15205472.
RA Qin J., Gao D. M., Jiang Q. F., Zhou Q., Kong Y. Y., Wang Y., Xie Y. H.
RT Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene.
RL Mol. Endocrinol. 18:2424-2439 (2004).
RN [4]; RE0053638.
RX PUBMED: 16488887.
RA Song K. H., Li T., Chiang J. Y.
RT A Prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4alpha that regulates the cholesterol 7alpha-hydroxylase gene.
RL J. Biol. Chem. 281:10081-10088 (2006).
RN [5]; RE0054989.
RX PUBMED: 15604093.
RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M.
RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.
RL Mol. Cell. Proteomics 4:205-213 (2005).
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