TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10523 XX ID T10523 XX DT 14.11.2005 (created); jma. DT 02.05.2016 (updated); smt. CO Copyright (C), QIAGEN. XX FA c-Ets-2 XX SY C-ets-2 protein; ETS-2. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G004958 ETS2; HGNC: Ets2. XX CL C0016; ETS; XX CP Unphosphorylated and Phosphorylated forms are highly expressed in MDA231 (breast tumor cell line) [2]. XX IN T08495 c-Ets-1; human, Homo sapiens. IN T00124 c-Fos; rat, Rattus norvegicus. IN T05669 c-Jun:c-Fos; rat, Rattus norvegicus. IN T00132 c-Jun; rat, Rattus norvegicus. IN T09446 c-Jun; Mammalia. IN T08562 CREB1; human, Homo sapiens. IN T08494 Erg; human, Homo sapiens. IN T22434 Prox-1-isoform1; human, Homo sapiens. IN T04922 Prox-1; human, Homo sapiens. IN T04632 SRC-1; human, Homo sapiens. IN T04640 SRC3; human, Homo sapiens. XX MX M02064 V$CETS2_02. MX M08759 V$ETS2_01. MX M07379 V$ETS2_Q4. MX M01207 V$ETS2_Q6. MX M08881 V$ETSLIKE_Q4. MX M00340 V$ETS_B. MX M00771 V$ETS_Q4. MX M00971 V$ETS_Q6. XX BS R29802. BS R26697. BS R25503. BS R25504. BS R21313. BS R36219. BS R73629. BS R26779. BS R26780. BS R32329. BS R73050. BS R30015. BS R65694. BS R23482. BS R61329. BS R26667. BS R37184. BS R14803. BS R29978. BS R27187. BS R64818. BS R34629. BS R34633. BS R21430. BS R25205. BS R29725. BS R58367. BS R34619. XX DR TRANSPATH: MO000056529. DR TRANSCOMPEL: C00640. DR UniProtKB: P15036; XX RN [1]; RE0016714. RX PUBMED: 9334186. RA Basuyaux J. P., Ferreira E., Stehelin D., Buttice G. RT The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner. RL J. Biol. Chem. 272:26188-26195 (1997). RN [2]; RE0030266. RX PUBMED: 12637547. RA Baker K. M., Wei G., Schaffner A. E., Ostrowski M. C. RT Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter. RL J. Biol. Chem. 278:17876-84 (2003). RN [3]; RE0030480. RX PUBMED: 14611815. RA Xiao X., Athanasiou M., Sidorov I. A., Horikawa I., Cremona G., Blair D., Barret J. C., Dimitrov D. S. RT Role of Ets/Id proteins for telomerase regulation in human cancer cells. RL Exp. Mol. Pathol. 75:238-47 (2003). RN [4]; RE0033804. RX PUBMED: 15294971. RA Takeshita F., Suzuki K., Sasaki S., Ishii N., Klinman D. M., Ishii K. J. RT Transcriptional regulation of the human TLR9 gene. RL J. Immunol. 173:2552-61 (2004). RN [5]; RE0048002. RX PUBMED: 15788656. RA Myers E., Hill A. D., Kelly G., McDermott E. W., O'Higgins N. J., Buggy Y., Young L. S. RT Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer. RL Clin. Cancer Res. 11:2111-2122 (2005). RN [6]; RE0048258. RX PUBMED: 12743594. RA Pei H., Yordy J. S., Leng Q., Zhao Q., Watson D. K., Li R. RT EAPII interacts with ETS1 and modulates its transcriptional function. RL Oncogene 22:2699-2709 (2003). RN [7]; RE0048279. RX PUBMED: 15637148. RA Ghosh D., Sachdev S., Hannink M., Roberts R. M. RT Coordinate regulation of basal and cyclic 5'-adenosine monophosphate (cAMP)-activated expression of human chorionic gonadotropin-alpha by Ets-2 and cAMP-responsive element binding protein. RL Mol. Endocrinol. 19:1049-1066 (2005). XX //