AC T10523
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ID T10523
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DT 14.11.2005 (created); jma.
DT 02.05.2016 (updated); smt.
CO Copyright (C), QIAGEN.
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FA c-Ets-2
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SY C-ets-2 protein; ETS-2.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G004958 ETS2; HGNC: Ets2.
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CL C0016; ETS; 3.5.2.1.2.
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CP Unphosphorylated and Phosphorylated forms are highly expressed in MDA231 (breast tumor cell line) [2].
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IN T08495 c-Ets-1; human, Homo sapiens.
IN T00124 c-Fos; rat, Rattus norvegicus.
IN T05669 c-Jun:c-Fos; rat, Rattus norvegicus.
IN T00132 c-Jun; rat, Rattus norvegicus.
IN T09446 c-Jun; Mammalia.
IN T08562 CREB1; human, Homo sapiens.
IN T08494 Erg; human, Homo sapiens.
IN T22434 Prox-1-isoform1; human, Homo sapiens.
IN T04922 Prox-1; human, Homo sapiens.
IN T04632 SRC-1; human, Homo sapiens.
IN T04640 SRC3; human, Homo sapiens.
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MX M02064 V$CETS2_02.
MX M08759 V$ETS2_01.
MX M07379 V$ETS2_Q4.
MX M01207 V$ETS2_Q6.
MX M08881 V$ETSLIKE_Q4.
MX M00340 V$ETS_B.
MX M00771 V$ETS_Q4.
MX M00971 V$ETS_Q6.
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BS R29802.
BS R26697.
BS R25503.
BS R25504.
BS R21313.
BS R36219.
BS R73629.
BS R26779.
BS R26780.
BS R32329.
BS R73050.
BS R30015.
BS R65694.
BS R23482.
BS R61329.
BS R26667.
BS R37184.
BS R14803.
BS R29978.
BS R27187.
BS R64818.
BS R34629.
BS R34633.
BS R21430.
BS R25205.
BS R29725.
BS R58367.
BS R34619.
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DR TRANSPATH: MO000056529.
DR TRANSCOMPEL: C00640.
DR UniProtKB: P15036;
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RN [1]; RE0016714.
RX PUBMED: 9334186.
RA Basuyaux J. P., Ferreira E., Stehelin D., Buttice G.
RT The Ets transcription factors interact with each other and with the c-Fos/c-Jun complex via distinct protein domains in a DNA-dependent and -independent manner.
RL J. Biol. Chem. 272:26188-26195 (1997).
RN [2]; RE0030266.
RX PUBMED: 12637547.
RA Baker K. M., Wei G., Schaffner A. E., Ostrowski M. C.
RT Ets-2 and components of mammalian SWI/SNF form a repressor complex that negatively regulates the BRCA1 promoter.
RL J. Biol. Chem. 278:17876-84 (2003).
RN [3]; RE0030480.
RX PUBMED: 14611815.
RA Xiao X., Athanasiou M., Sidorov I. A., Horikawa I., Cremona G., Blair D., Barret J. C., Dimitrov D. S.
RT Role of Ets/Id proteins for telomerase regulation in human cancer cells.
RL Exp. Mol. Pathol. 75:238-47 (2003).
RN [4]; RE0033804.
RX PUBMED: 15294971.
RA Takeshita F., Suzuki K., Sasaki S., Ishii N., Klinman D. M., Ishii K. J.
RT Transcriptional regulation of the human TLR9 gene.
RL J. Immunol. 173:2552-61 (2004).
RN [5]; RE0048002.
RX PUBMED: 15788656.
RA Myers E., Hill A. D., Kelly G., McDermott E. W., O'Higgins N. J., Buggy Y., Young L. S.
RT Associations and interactions between Ets-1 and Ets-2 and coregulatory proteins, SRC-1, AIB1, and NCoR in breast cancer.
RL Clin. Cancer Res. 11:2111-2122 (2005).
RN [6]; RE0048258.
RX PUBMED: 12743594.
RA Pei H., Yordy J. S., Leng Q., Zhao Q., Watson D. K., Li R.
RT EAPII interacts with ETS1 and modulates its transcriptional function.
RL Oncogene 22:2699-2709 (2003).
RN [7]; RE0048279.
RX PUBMED: 15637148.
RA Ghosh D., Sachdev S., Hannink M., Roberts R. M.
RT Coordinate regulation of basal and cyclic 5'-adenosine monophosphate (cAMP)-activated expression of human chorionic gonadotropin-alpha by Ets-2 and cAMP-responsive element binding protein.
RL Mol. Endocrinol. 19:1049-1066 (2005).
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