TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T02770 XX ID T02770 XX DT 08.06.1999 (created); mpr. DT 01.02.2016 (updated); mom. CO Copyright (C), QIAGEN. XX FA LRH-1 XX SY alpha-1-fetoprotein transcription factor; B1-binding factor; B1F; B1F2; CPF; CYP7A promoter binding factor; fetoprotein transcription factor; FTF; Ftz-F1; FTZ-F1beta; HB1F; hB1F-2; hepatocytic transcription factor; liver receptor homologous protein; LRH-1; LRH1; NR5A2; nuclear receptor subfamily 5, group A, member 2. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G002482 NR5A2; HGNC: NR5A2. XX CL C0002; CC (rec); XX SF variants are T08492 and T08525; XX EX brain,,,adult; none; Northern blot; RNA (undefined); [3]. EX heart,,,adult; low; Northern blot; RNA (undefined); [3]. EX kidney (right and left),,,adult; none; Northern blot; RNA (undefined); [3]. EX liver,,,adult; high; Northern blot; RNA (undefined); [3]. EX lung (right and left),,,adult; low; Northern blot; RNA (undefined); [3]. EX muscles,,,adult; none; Northern blot; RNA (undefined); [3]. EX pancreas,,,adult; high; Northern blot; RNA (undefined); [3]. EX placenta,,,adult; none; Northern blot; RNA (undefined); [3]. XX IN T02872 beta-catenin; human, Homo sapiens. IN T11171 foxl2; human, Homo sapiens. IN T02716 GATA-4; rat, Rattus norvegicus. IN T02717 GATA-6; rat, Rattus norvegicus. IN T04922 Prox-1; human, Homo sapiens. IN T02738 SHP; human, Homo sapiens. IN T08947 SHP; mouse, Mus musculus. IN T04632 SRC-1; human, Homo sapiens. XX MX M01142 V$LRH1_Q5. MX M02098 V$LRH1_Q5_01. MX M07360 V$LRH1_Q6. XX BS R27834. BS R20900. BS R20902. BS R22990. BS R28957. BS R28955. BS R28817. BS R28910. BS R23036. BS R27822. BS R23905. BS R24513. BS R39435. BS R39436. BS R39437. BS R19636. BS R28701. BS R28702. BS R71681. BS R56046. BS R67513. BS R67514. BS R67515. BS R29090. BS R29112. BS R27897. BS R39438. BS R29154. BS R29120. XX DR TRANSPATH: MO000026742. DR UniProtKB: O00482; XX RN [1]; RE0013625. RX PUBMED: 10219237. RA Nuclear Receptors Nomenclature Committee. RT A unified nomenclature system for the nuclear receptor superfamily RL Cell 97:161-163 (1999). RN [2]; RE0013659. RX PUBMED: 9858833. RA Galarneau L., Drouin R., Belanger L. RT Assignment of the fetoprotein transcription factor gene (FTF) to human chromosome band 1q32.11 by in situ hybridization RL Cytogenet. Cell Genet. 82:269-270 (1998). RN [3]; RE0016199. RX PUBMED: 10359768. RA Nitta M., Ku S., Brown C., Okamoto A. Y., Shan B. RT CPF: an orphan nuclear receptor that regulates liver-specific expression of the human cholesterol 7alpha-hydroxylase gene RL Proc. Natl. Acad. Sci. USA 96:6660-6665 (1999). RN [4]; RE0036094. RX PUBMED: 15928316. RA Martin L. J., Taniguchi H., Robert N. M., Simard J., Tremblay J. J., Viger R. S. RT GATA factors and the nuclear receptors, steroidogenic factor 1/liver receptor homolog 1, are key mutual partners in the regulation of the human 3beta-hydroxysteroid dehydrogenase type 2 promoter. RL Mol. Endocrinol. 19:2358-2370 (2005). RN [5]; RE0042891. RX PUBMED: 12198243. RA Brendel C., Schoonjans K., Botrugno O. A., Treuter E., Auwerx J. RT The Small Heterodimer Partner Interacts with the Liver X Receptor alpha and Represses Its Transcriptional Activity RL Mol. Endocrinol. 16:2065-76 (2002). RN [6]; RE0047682. RX PUBMED: 12040021. RA Brendel C., Gelman L., Auwerx J. RT Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism. RL Mol. Endocrinol. 16:1367-1377 (2002). RN [7]; RE0049388. RX PUBMED: 15923626. RA Chalkiadaki A., Talianidis I. RT SUMO-dependent compartmentalization in promyelocytic leukemia protein nuclear bodies prevents the access of LRH-1 to chromatin. RL Mol. Cell. Biol. 25:5095-5105 (2005). RN [8]; RE0051247. RX PUBMED: 11518759. RA Chen W., Owsley E., Yang Y., Stroup D., Chiang J. Y. RT Nuclear receptor-mediated repression of human cholesterol 7alpha-hydroxylase gene transcription by bile acids. RL J. Lipid Res. 42:1402-1412 (2001). RN [9]; RE0053152. RX PUBMED: 15205472. RA Qin J., Gao D. M., Jiang Q. F., Zhou Q., Kong Y. Y., Wang Y., Xie Y. H. RT Prospero-related homeobox (Prox1) is a corepressor of human liver receptor homolog-1 and suppresses the transcription of the cholesterol 7-alpha-hydroxylase gene. RL Mol. Endocrinol. 18:2424-2439 (2004). RN [10]; RE0054989. RX PUBMED: 15604093. RA Albers M., Kranz H., Kober I., Kaiser C., Klink M., Suckow J., Kern R., Koegl M. RT Automated yeast two-hybrid screening for nuclear receptor-interacting proteins. RL Mol. Cell. Proteomics 4:205-213 (2005). XX //