TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T02872 XX ID T02872 XX DT 12.01.2000 (created); sur. DT 11.11.2016 (updated); mkl. CO Copyright (C), QIAGEN. XX FA beta-catenin XX SY catenin (cadherin-associated protein), beta 1, 88kDa; CTNNB; CTNNB1; DKFZp686D02253; FLJ25606; FLJ37923; OK/SW-cl.35. XX OS human, Homo sapiens OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates XX GE G001701 CTNNB1; HGNC: CTNNB1. XX HO armadillo (Drosophila melanogaster). XX SF E-cadherin and APC compete for binding to beta-catenin; SF armadillo-like repeats mediate the interaction with E-cadherin [6]; SF 13 armadillo-like repeats, with the N terminal repeats 1-7 being partly sufficient for interaction with LEF-1 [1]; SF gene: CTNNB1, 16 exons with an alternative splicing site within exon 16 which produced a splice variant that is 159-bp shorter in the 3'-prime untranslated region [64]; SF 5' flanking region contain potential binding sites for several transcription factors such as NFkappaB, SP1, AP2 and EGR1 [7]; SF binds to pontin52 which also binds to the TBP (TATA box binding protein) [9]; SF for nuclear localization of endogenous beta-catenin expression of LEF-1 and a Wnt-1 signal were found both to be required [10]; SF beta-catenin lacking aa 1-131 or having aa substitutions in the N terminus (S33->A, S37->A, T40->A, S45->A, S47->A) showed higher activation of a reporter gene than the wt beta-catenin [10]; SF unless it possesses no nuclear localization sequence (NLS) it can translocated to the nucleus independently of interaction with TCF/ LEF transcription factors [11]; XX EX brain,,,adult; detectable. EX brain,,,adult; detectable. EX brain,,,adult; detectable. XX FF beta-catenin links E-cadherin and APC to the cytoskeleton-associated protein alpha-catenin. Thus it represents an important link in the communication between cell adhesion, cytoskeletal interaction, and tumor progression; FF deregulation of beta-catenin signaling can lead to different types of cancer [5]; FF amino- and carboxyl- terminal regions of beta-catenin contain transcriptional activation domains which could function in a heterologous context by collaboration with one another of with LEF-1 [10]; FF the transcriptional activation domains of beta-catenin can functionally collaborate with protein domains of DNA-bound LEF-1 to stimulate transcription [10]; FF beta-catenin stabilizing mutations result in LEF-1 transactivation leading to development of human tumours of hair matrix differentiation [4]; XX IN T15601 AR; Mammalia. IN T18378 CBP; human, Homo sapiens. IN T00250 Elk-1; human, Homo sapiens. IN T02938 FOXO3a; human, Homo sapiens. IN T14002 GKLF; mouse, Mus musculus. IN T14243 GKLF; human, Homo sapiens. IN T00433 ITF-2; human, Homo sapiens. IN T08297 Kaiso; human, Homo sapiens. IN T02905 LEF-1-isoform1; human, Homo sapiens. IN T00930 LEF-1; mouse, Mus musculus. IN T16141 LEF-1; human, Homo sapiens. IN T02770 LRH-1; human, Homo sapiens. IN T01443 Nrf2; human, Homo sapiens. IN T02767 Nur77; human, Homo sapiens. IN T21984 p300; human, Homo sapiens. IN T23091 p300; Mammalia. IN T06132 p63-isoform1; human, Homo sapiens. IN T03214 Pontin52; human, Homo sapiens. IN T34674 prohibitin-2; human, Homo sapiens. IN T01345 RXR-alpha; human, Homo sapiens. IN T04096 Smad3-isoform1; human, Homo sapiens. IN T04292 Smad4; human, Homo sapiens. IN T22380 Smad7; Mammalia. IN T06312 SNA; human, Homo sapiens. IN T15014 SNA; human, Homo sapiens. IN T06029 Sox-17; mouse, Mus musculus. IN T06030 Sox-17; human, Homo sapiens. IN T01109 TCF-1(P); mouse, Mus musculus. IN T02857 TCF-3; clawed frog, Xenopus laevis. IN T02861 TCF-3C; clawed frog, Xenopus laevis. IN T02862 TCF-3D; clawed frog, Xenopus laevis. IN T02918 TCF-4; human, Homo sapiens. IN T16010 TCF-4; Mammalia. IN T02917 TCF-4B; human, Homo sapiens. IN T02878 TCF-4E; human, Homo sapiens. IN T02483 TIF2; human, Homo sapiens. IN T25956 YAP-isoform2; human, Homo sapiens. IN T22876 YAP; human, Homo sapiens. XX MX M03539 V$BETACATENIN_Q3. MX M07376 V$BETACATENIN_Q3_01. MX M07035 V$BETACATENIN_Q6. MX M07599 V$BETACATENIN_Q6_01. XX BS R67620. BS R36821. BS R08646. BS R58003. BS R67625. BS R32371. BS R58010. BS R66716. BS R66717. BS R66719. BS R66720. BS R72968. BS R72972. BS R72973. BS R58479. BS R27836. BS R27838. BS R56941. BS R67667. BS R67668. BS R67669. BS R67663. BS R67664. BS R38813. BS R35535. BS R61549. XX DR TRANSPATH: MO000017049. DR PATHODB: MT010399. DR PATHODB: MT010400. DR PATHODB: MT010401. DR PATHODB: MT010402. DR PATHODB: MT010403. DR PATHODB: MT010404. DR PATHODB: MT010405. DR PATHODB: MT010406. DR PATHODB: MT010407. DR PATHODB: MT010408. DR PATHODB: MT010409. DR PATHODB: MT010410. DR PATHODB: MT010411. DR PATHODB: MT010412. DR PATHODB: MT010413. DR PATHODB: MT010414. DR PATHODB: MT010415. DR PATHODB: MT010416. DR PATHODB: MT010417. DR PATHODB: MT010418. DR PATHODB: MT010419. DR PATHODB: MT010420. DR PATHODB: MT010421. DR PATHODB: MT010422. DR PATHODB: MT010423. DR PATHODB: MT010424. DR PATHODB: MT010425. DR PATHODB: MT010426. DR PATHODB: MT010427. DR PATHODB: MT010428. DR PATHODB: MT010429. DR PATHODB: MT010430. DR PATHODB: MT010431. DR PATHODB: MT010432. DR PATHODB: MT010433. DR PATHODB: MT010434. DR PATHODB: MT010435. DR PATHODB: MT010436. DR PATHODB: MT010437. DR PATHODB: MT010438. DR PATHODB: MT010439. DR PATHODB: MT010441. DR PATHODB: MT010442. DR PATHODB: MT010443. DR PATHODB: MT010444. DR PATHODB: MT010445. DR PATHODB: MT010446. DR PATHODB: MT010447. DR PATHODB: MT010448. DR PATHODB: MT010449. DR PATHODB: MT010450. DR PATHODB: MT010451. DR PATHODB: MT010452. DR PATHODB: MT010453. DR PATHODB: MT010454. DR PATHODB: MT010455. DR PATHODB: MT010456. DR PATHODB: MT010457. DR PATHODB: MT010458. DR PATHODB: MT010459. DR PATHODB: MT010460. DR PATHODB: MT010461. DR PATHODB: MT010462. DR PATHODB: MT010463. DR PATHODB: MT010464. DR PATHODB: MT010465. DR PATHODB: MT010466. DR PATHODB: MT010467. DR PATHODB: MT010468. DR PATHODB: MT010469. DR PATHODB: MT010470. DR PATHODB: MT010486. DR PATHODB: MT010487. DR PATHODB: MT010488. DR PATHODB: MT010489. DR PATHODB: MT010664. DR PATHODB: MT010670. DR PATHODB: MT010671. DR PATHODB: MT010672. DR PATHODB: MT010673. DR UniProtKB: P35222; XX RN [1]; RE0006108. RX PUBMED: 8757136. RA Behrens J., von Kries J. P., Kuehl M., Bruhn L., Wedlich D., Grosschedl R., Birchmeier W. RT Functional interaction of beta-catenin with the transcription factor LEF -1 RL Nature 382:638-642 (1996). RN [2]; RE0006329. RX PUBMED: 9065402. RA Morin P. J., Sparks A. B., Korinek V., Barker N., Clevers H., Vogelstein B., Kinzler K. W. RT Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC RL Science 275:1787-1790 (1997). RN [3]; RE0006331. RX PUBMED: 9065403. RA Rubinfeld B., Robbins P., El-Gamil M., Albert I., Porfiri E., Polakis P. RT Stabilization of beta-catenin by genetic defects in melanoma cell lines RL Science 275:1790-1792 (1997). RN [4]; RE0014096. RX PUBMED: 10192393. RA Chan E. F., Gat U., McNiff J. M., Fuchs E. RT A common human skin tumour is caused by activating mutations in beta-catenin RL Nat. Genet. 21:410-413 (1999). RN [5]; RE0014117. RX PUBMED: 10580987. RA Morin P. J. RT Beta-catenin signaling and cancer RL BioEssays 21:1021-1030 (1999). RN [6]; RE0014125. RX PUBMED: 7806582. RA Hulsken J., Birchmeier W., Behrens J. RT E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton RL J. Cell Biol. 127:2061-2069 (1994). RN [7]; RE0014174. RX PUBMED: 8838805. RA Nollet F., Berx G., Molemans F., van Roy F. RT Genomic organization of the human beta-catenin gene (CTNNB1) RL Genomics 32:413-424 (1996). RN [8]; RE0014185. RX PUBMED: 8892228. RA Huber O., Korn R., McLaughlin J., Ohsugi M., Herrmann B. G., Kemler R. RT Nuclear localization of beta-catenin by interaction with transcription factor LEF-1 RL Mech. Dev. 59:3-10 (1996). RN [9]; RE0014262. RX PUBMED: 9843967. RA Bauer A., Huber O., Kemler R. RT Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein RL Proc. Natl. Acad. Sci. USA 95:14787-14792 (1998). RN [10]; RE0014336. RX PUBMED: 9671490. RA Hsu S.-C., Galceran J., Grosschedl R. RT Modulation of transcriptional regulation by LEF-1 in response to Wnt-1 signaling and association with beta-catenin RL Mol. Cell. Biol. 18:4807-4818 (1998). RN [11]; RE0014348. RX PUBMED: 9501980. RA Fagotto F., Gluck U., Gumbiner B. M. RT Nuclear localization signal-independent and importin/karyopherin-independent nuclear import of beta-catenin RL Curr. Biol. 12:181-190 (1998). RN [12]; RE0014350. RX PUBMED: 7907279. RA Peifer M., Berg S., Reynolds A. B. RT A repeating amino acid motif shared by proteins with diverse cellular roles RL Cell 76:789-791 (1994). RN [13]; RE0018458. RX PUBMED: 10477752. RA Espada J., Perez-Moreno M., Braga V. M., Rodriguez-Viciana P., Cano A. RT H-Ras activation promotes cytoplasmic accumulation and phosphoinositide 3-OH kinase association of beta-catenin in epidermal keratinocytes RL J. Cell Biol. 146:967-980 (1999). RN [14]; RE0018717. RX PUBMED: 10772923. RA Dobrosotskaya I. Y., James G. L. RT MAGI-1 interacts with beta-catenin and is associated with cell-cell adhesion structures RL Biochem. Biophys. Res. Commun. 270:903-909 (2000). RN [15]; RE0021674. RX PUBMED: 9497337. RA Ozawa M., Kemler R. RT Altered cell adhesion activity by pervanadate due to the dissociation of alpha-catenin from the E-cadherin.catenin complex RL J. Biol. Chem. 273:6166-6170 (1998). RN [16]; RE0031565. RX PUBMED: 14638683. RA Li H., Kim J. H., Koh S. S., Stallcup M. R. RT Synergistic effects of coactivators GRIP1 and beta-catenin on gene activation: cross-talk between androgen receptor and Wnt signaling pathways. RL J. Biol. Chem. 279:4212-20 (2004). RN [17]; RE0031743. RX PUBMED: 11792709. RA Yang F., Li X., Sharma M., Sasaki C. Y., Longo D. L., Lim B., Sun Z. RT Linking beta-catenin to androgen-signaling pathway. RL J. Biol. Chem. 277:11336-44 (2002). RN [18]; RE0032212. RX PUBMED: 12571228. RA Duchesne C., Charland S., Asselin C., Nahmias C., Rivard N. RT Negative regulation of beta-catenin signaling by tyrosine phosphatase SHP-1 in intestinal epithelial cells. RL J. Biol. Chem. 278:14274-83 (2003). RN [19]; RE0035178. RX PUBMED: 11463391. RA Yu J., Zhang L., Hwang P. M., Kinzler K. W., Vogelstein B. RT PUMA induces the rapid apoptosis of colorectal cancer cells. RL Mol. Cell 7:673-682 (2001). RN [20]; RE0037059. RX PUBMED: 10769211. RA Hanakawa Y., Amagai M., Shirakata Y., Sayama K., Hashimoto K. RT Different effects of dominant negative mutants of desmocollin and desmoglein on the cell-cell adhesion of keratinocytes RL J. Cell Sci. 113:1803-11 (2000). RN [21]; RE0038022. RX PUBMED: 11590244. RA Janssens B., Goossens S., Staes K., Gilbert B., van Hengel J., Colpaert C., Bruyneel E., Mareel M., van Roy F. RT alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion RL J. Cell Sci. 114:3177-88 (2001). RN [22]; RE0040482. RX PUBMED: 12692135. RA Fomenkov A., Huang Y. P., Topaloglu O., Brechman A., Osada M., Fomenkova T., Yuriditsky E., Trink B., Sidransky D., Ratovitski E. RT P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome RL J. Biol. Chem. 278:23906-14 (2003). RN [23]; RE0047144. RX PUBMED: 15256534. RA Masiello D., Chen S. Y., Xu Y., Verhoeven M. C., Choi E., Hollenberg A. N., Balk S. P. RT Recruitment of beta-catenin by wild-type or mutant androgen receptors correlates with ligand-stimulated growth of prostate cancer cells RL Mol. Endocrinol. 18:2388-401 (2004). RN [24]; RE0047219. RX PUBMED: 15604245. RA Verras M., Brown J., Li X., Nusse R., Sun Z. RT Wnt3a growth factor induces androgen receptor-mediated transcription and enhances cell growth in human prostate cancer cells RL Cancer Res. 64:8860-6 (2004). RN [25]; RE0049966. RX PUBMED: 12003790. RA Shasby D. M., Ries D. R., Shasby S. S., Winter M. C. RT Histamine stimulates phosphorylation of adherens junction proteins and alters their link to vimentin. RL Am. J. Physiol. Lung Cell. Mol. Physiol. 282:L1330-1338 (2002). RN [26]; RE0050482. RX PUBMED: 16707106. RA Uemura K., Kihara T., Kuzuya A., Okawa K., Nishimoto T., Bito H., Ninomiya H., Sugimoto H., Kinoshita A., Shimohama S. RT Activity-dependent regulation of beta-catenin via epsilon-cleavage of N-cadherin. RL Biochem. Biophys. Res. Commun. 345:951-958 (2006). RN [27]; RE0050795. RX PUBMED: 12939402. RA Li Y., Yu W. H., Ren J., Chen W., Huang L., Kharbanda S., Loda M., Kufe D. RT Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein. RL Mol. Cancer Res. 1:765-775 (2003). RN [28]; RE0052383. RX PUBMED: 16724116. RA Valenta T., Lukas J., Doubravska L., Fafilek B., Korinek V. RT HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. RL EMBO J. 25:2326-2337 (2006). RN [29]; RE0052860. RX PUBMED: 17283121. RA Idogawa M., Masutani M., Shitashige M., Honda K., Tokino T., Shinomura Y., Imai K., Hirohashi S., Yamada T. RT Ku70 and poly(ADP-ribose) polymerase-1 competitively regulate beta-catenin and T-cell factor-4-mediated gene transactivation: possible linkage of DNA damage recognition and Wnt signaling. RL Cancer Res. 67:911-918 (2007). RN [30]; RE0054638. RX PUBMED: 18593713. RA Tang Y., Liu Z., Zhao L., Clemens T. L., Cao X. RT Smad7 stabilizes beta-catenin binding to E-cadherin complex and promotes cell-cell adhesion. RL J. Biol. Chem. 283:23956-23963 (2008). RN [31]; RE0054809. RX PUBMED: 16288032. RA Huang L., Chen D., Liu D., Yin L., Kharbanda S., Kufe D. RT MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin. RL Cancer Res. 65:10413-10422 (2005). RN [32]; RE0062741. RX PUBMED: 18086858. RA Bahmanyar S., Kaplan D. D., Deluca J. G., Giddings TH J. r., O'Toole E. T., Winey M., Salmon E. D., Casey P. J., Nelson W. J., Barth A. I. RT beta-Catenin is a Nek2 substrate involved in centrosome separation. RL Genes Dev. 22:91-105 (2008). RN [33]; RE0062827. RX PUBMED: 19443654. RA Hong C. F., Chou Y. T., Lin Y. S., Wu C. W. RT MAD2B, a novel TCF4-binding protein, modulates TCF4-mediated epithelial-mesenchymal transdifferentiation. RL J. Biol. Chem. 284:19613-19622 (2009). RN [34]; RE0064539. RX PUBMED: 18451303. RA Thornton T. M., Pedraza-Alva G., Deng B., Wood C. D., Aronshtam A., Clements J. L., Sabio G., Davis R. J., Matthews D. E., Doble B., Rincon M. RT Phosphorylation by p38 MAPK as an alternative pathway for GSK3beta inactivation. RL Science 320:667-670 (2008). RN [35]; RE0065560. RX PUBMED: 19038973. RA Wang H. X., Tekpetey F. R., Kidder G. M. RT Identification of WNT/beta-CATENIN signaling pathway components in human cumulus cells. RL Mol. Hum. Reprod. 15:11-17 (2009). RN [36]; RE0065601. RX PUBMED: 19244247. RA Medrek C., Landberg G., Andersson T., Leandersson K. RT Wnt-5a-CKI{alpha} signaling promotes {beta}-catenin/E-cadherin complex formation and intercellular adhesion in human breast epithelial cells. RL J. Biol. Chem. 284:10968-10979 (2009). RN [37]; RE0065788. RX PUBMED: 19198599. RA Kajiro M., Hirota R., Nakajima Y., Kawanowa K., So-ma K., Ito I., Yamaguchi Y., Ohie S. H., Kobayashi Y., Seino Y., Kawano M., Kawabe Y., Takei H., Hayashi S., Kurosumi M., Murayama A., Kimura K., Yanagisawa J. RT The ubiquitin ligase CHIP acts as an upstream regulator of oncogenic pathways. RL Nat. Cell Biol. 11:312-319 (2009). RN [38]; RE0066118. RX PUBMED: 20048167. RA Adam A. P., Sharenko A. L., Pumiglia K., Vincent P. A. RT Src-induced Tyrosine Phosphorylation of VE-cadherin Is Not Sufficient to Decrease Barrier Function of Endothelial Monolayers. RL J. Biol. Chem. 285:7045-7055 (2010). RN [39]; RE0066141. RX PUBMED: 19477926. RA Binnerts M. E., Tomasevic N., Bright J. M., Leung J., Ahn V. E., Kim K. A., Zhan X., Liu S., Yonkovich S., Williams J., Zhou M., Gros D., Dixon M., Korver W., Weis W. I., Abo A. RT The first propeller domain of LRP6 regulates sensitivity to DKK1. RL Mol. Biol. Cell 20:3552-3560 (2009). RN [40]; RE0066171. RX PUBMED: 17159916. RA Yamaguchi Y., Passeron T., Watabe H., Yasumoto K., Rouzaud F., Hoashi T., Hearing V. J. RT The effects of dickkopf 1 on gene expression and Wnt signaling by melanocytes: mechanisms underlying its suppression of melanocyte function and proliferation. RL J. Invest. Dermatol 127:1217-1225 (2007). RN [41]; RE0066261. RX PUBMED: 18936100. RA Gao X., Wen J., Zhang L., Li X., Ning Y., Meng A., Chen Y. G. RT Dapper1 is a nucleocytoplasmic shuttling protein that negatively modulates Wnt signaling in the nucleus. RL J. Biol. Chem. 283:35679-35688 (2008). RN [42]; RE0066482. RX PUBMED: 16571670. RA Bachar-Dahan L., Goltzmann J., Yaniv A., Gazit A. RT Engrailed-1 negatively regulates beta-catenin transcriptional activity by destabilizing beta-catenin via a glycogen synthase kinase-3beta-independent pathway. RL Mol. Biol. Cell 17:2572-2580 (2006). RN [43]; RE0066740. RX PUBMED: 18667832. RA Ress A., Moelling K. RT The PDZ protein erbin modulates beta-catenin-dependent transcription. RL Eur. Surg. Res. 41:284-289 (2008). RN [44]; RE0067112. RX PUBMED: 17875931. RA Sinner D., Kordich J. J., Spence J. R., Opoka R., Rankin S., Lin S. C., Jonatan D., Zorn A. M., Wells J. M. RT Sox17 and Sox4 differentially regulate beta-catenin/T-cell factor activity and proliferation of colon carcinoma cells. RL Mol. Cell. Biol. 27:7802-7815 (2007). RN [45]; RE0068708. RX PUBMED: 20307497. RA Kim E. A., Kim J. E., Sung K. S., Choi D. W., Lee B. J., Choi C. Y. RT Homeodomain-interacting protein kinase 2 (HIPK2) targets beta-catenin for phosphorylation and proteasomal degradation. RL Biochem. Biophys. Res. Commun. 394:966-971 (2010). RN [46]; RE0069589. RX PUBMED: 20862283. RA Lovatt M., Bijlmakers M. J. RT Stabilisation of beta-catenin downstream of T cell receptor signalling. RL PLoS ONE 5:e12794 (2010). RN [47]; RE0070036. RX PUBMED: 21118991. RA Hay-Koren A., Caspi M., Zilberberg A., Rosin-Arbesfeld R. RT The EDD E3 ubiquitin ligase ubiquitinates and up-regulates beta-catenin. RL Mol. Biol. Cell 22:399-411 (2011). RN [48]; RE0070462. RX PUBMED: 20519433. RA Harris E. S., Nelson W. J. RT Adenomatous polyposis coli regulates endothelial cell migration independent of roles in beta-catenin signaling and cell-cell adhesion. RL Mol. Biol. Cell 21:2611-2623 (2010). RN [49]; RE0070502. RX PUBMED: 21303975. RA Al-Mulla F., Bitar M. S., Al-Maghrebi M., Behbehani A. I., Al-Ali W., Rath O., Doyle B., Tan K. Y., Pitt A., Kolch W. RT Raf kinase inhibitor protein RKIP enhances signaling by glycogen synthase kinase-3beta. RL Cancer Res. 71:1334-1343 (2011). RN [50]; RE0071171. RX PUBMED: 16007092. RA Martin M., Rehani K., Jope R. S., Michalek S. M. RT Toll-like receptor-mediated cytokine production is differentially regulated by glycogen synthase kinase 3. RL Nat. Immunol. 6:777-784 (2005). RN [51]; RE0071192. RX PUBMED: 15371335. RA Brembeck F. H., Schwarz-Romond T., Bakkers J., Wilhelm S., Hammerschmidt M., Birchmeier W. RT Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions. RL Genes Dev. 18:2225-2230 (2004). RN [52]; RE0071383. RX PUBMED: 7790378. RA Knudsen K. A., Soler A. P., Johnson K. R., Wheelock M. J. RT Interaction of alpha-actinin with the cadherin/catenin cell-cell adhesion complex via alpha-catenin. RL J. Cell Biol. 130:67-77 (1995). RN [53]; RE0071402. RX PUBMED: 20086044. RA Peng X., Cuff L. E., Lawton C. D., DeMali K. A. RT Vinculin regulates cell-surface E-cadherin expression by binding to beta-catenin. RL J. Cell Sci. 123:567-577 (2010). RN [54]; RE0071464. RX PUBMED: 10629228. RA Thoreson M. A., Anastasiadis P. Z., Daniel J. M., Ireton R. C., Wheelock M. J., Johnson K. R., Hummingbird D. K., Reynolds A. B. RT Selective uncoupling of p120(ctn) from E-cadherin disrupts strong adhesion. RL J. Cell Biol. 148:189-202 (2000). RN [55]; RE0071489. RX PUBMED: 17996206. RA Marchesini N., Jones J. A., Hannun Y. A. RT Confluence induced threonine41/serine45 phospho-beta-catenin dephosphorylation via ceramide-mediated activation of PP1cgamma. RL Biochim. Biophys. Acta 1771:1418-1428 (2007). RN [56]; RE0071593. RX PUBMED: 11716761. RA Woodfield R. J., Hodgkin M. N., Akhtar N., Morse M. A., Fuller K. J., Saqib K., Thompson N. T., Wakelam M. J. RT The p85 subunit of phosphoinositide 3-kinase is associated with beta-catenin in the cadherin-based adhesion complex. RL Biochem. J. 360:335-344 (2001). RN [57]; RE0071618. RX PUBMED: 19001871. RA Arai T., Haze K., Iimura-Morita Y., Machida T., Iida M., Tanaka K., Komatani H. RT Identification of beta-catenin as a novel substrate of Polo-like kinase 1. RL Cell Cycle 7:3556-3563 (2008). RN [58]; RE0071692. RX PUBMED: 21730131. RA Kim N. G., Koh E., Chen X., Gumbiner B. M. RT E-cadherin mediates contact inhibition of proliferation through Hippo signaling-pathway components. RL Proc. Natl. Acad. Sci. USA 108:11930-11935 (2011). RN [59]; RE0071696. RX PUBMED: 17318191. RA Coluccia A. M., Vacca A., Dunach M., Mologni L., Redaelli S., Bustos V. H., Benati D., Pinna L. A., Gambacorti-Passerini C. RT Bcr-Abl stabilizes beta-catenin in chronic myeloid leukemia through its tyrosine phosphorylation. RL EMBO J. 26:1456-1466 (2007). RN [60]; RE0071936. RX PUBMED: 15905404. RA Essers M. A., de Vries-Smits L. M., Barker N., Polderman P. E., Burgering B. M., Korswagen H. C. RT Functional interaction between beta-catenin and FOXO in oxidative stress signaling. RL Science 308:1181-1184 (2005). RN [61]; RE0072503. RX PUBMED: 20840866. RA Simoneau M., Coulombe G., Vandal G., Vezina A., Rivard N. RT SHP-1 inhibits beta-catenin function by inducing its degradation and interfering with its association with TATA-binding protein. RL Cell. Signal. 23:269-279 (2011). RN [62]; RE0072530. RX PUBMED: 16648485. RA Anders L., Mertins P., Lammich S., Murgia M., Hartmann D., Saftig P., Haass C., Ullrich A. RT Furin-, ADAM 10-, and gamma-secretase-mediated cleavage of a receptor tyrosine phosphatase and regulation of beta-catenin's transcriptional activity. RL Mol. Cell. Biol. 26:3917-3934 (2006). RN [63]; RE0073076. RX PUBMED: 22194609. RA Chervin-Petinot A., Courcon M., Almagro S., Nicolas A., Grichine A., Grunwald D., Prandini M. H., Huber P., Gulino-Debrac D. RT Epithelial Protein Lost In Neoplasm (EPLIN) Interacts with alpha-Catenin and Actin Filaments in Endothelial Cells and Stabilizes Vascular Capillary Network in Vitro. RL J. Biol. Chem. 287:7556-7572 (2012). RN [64]; RE0000035. RX PUBMED: 6537904. RA Parker C. S., Topol J. RT A Drosophila RNA polymerase II transcription factor contains a promoter-region-specific DNA-binding activity RL Cell 36:357-369 (1984). XX //