AC T16141
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ID T16141
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DT 30.06.2009 (created); apk.
DT 07.12.2015 (updated); sup.
CO Copyright (C), QIAGEN.
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FA LEF-1
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SY hLEF-1; human LEF-1; Lymphocyte enhancer binding factor 1; lymphoid enhancer binding factor 1; lymphoid enhancing factor 1; TCF-1alpha; TCF1-alpha; transcription factor 1-alpha.
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OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
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GE G013559 LEF1; HGNC: Lef1.
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CL C0015; HMG; 4.1.3.0.4.
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IN T10136 ATF-2; human, Homo sapiens.
IN T18797 ATFa; human, Homo sapiens.
IN T02872 beta-catenin; human, Homo sapiens.
IN T14513 beta-catenin; Mammalia.
IN T00241 Egr-1; human, Homo sapiens.
IN T23418 HDAC1; mouse, Mus musculus.
IN T13873 MITF; Mammalia.
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MX M00978 V$LEF1TCF1_Q4.
MX M04003 V$LEF1_05.
MX M05489 V$LEF1_06.
MX M08948 V$LEF1_07.
MX M00805 V$LEF1_Q2.
MX M01022 V$LEF1_Q2_01.
MX M07046 V$LEF1_Q3.
MX M07605 V$LEF1_Q4.
MX M02019 V$LEF1_Q5.
MX M03794 V$LEF1_Q5_01.
MX M08902 V$TCF7RELATED_Q4.
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BS R28281.
BS R35952.
BS R35953.
BS R38036.
BS R38037.
BS R65990.
BS R28283.
BS R28290.
BS R31602.
BS R31603.
BS R68236.
BS R68237.
BS R68238.
BS R68239.
BS R70598.
BS R70600.
BS R70602.
BS R70603.
BS R70604.
BS R70607.
BS R70597.
BS R40750.
BS R31116.
BS R31117.
BS R60921.
BS R30947.
BS R33870.
BS R28356.
BS R30795.
BS R40433.
BS R66394.
BS R66395.
BS R66400.
BS R25773.
BS R71211.
BS R28447.
BS R18881.
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DR TRANSPATH: MO000159782.
DR UniProtKB: Q9UJU2;
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RN [1]; RE0023725.
RX PUBMED: 12556497.
RA Ishitani T., Ninomiya-Tsuji J., Matsumoto K.
RT Regulation of lymphoid enhancer factor 1/T-cell factor by mitogen-activated protein kinase-related Nemo-like kinase-dependent phosphorylation in Wnt/beta-catenin signaling.
RL Mol. Cell. Biol. 23:1379-1389 (2003).
RN [2]; RE0024474.
RX PUBMED: 12048204.
RA Saito H., Yasumoto K., Takeda K., Takahashi K., Fukuzaki A., Orikasa S., Shibahara S.
RT Melanocyte-specific microphthalmia-associated transcription factor isoform activates its own gene promoter through physical interaction with lymphoid-enhancing factor 1.
RL J. Biol. Chem. 277:28787-28794 (2002).
RN [3]; RE0024475.
RX PUBMED: 12032083.
RA Yasumoto K., Takeda K., Saito H., Watanabe K., Takahashi K., Shibahara S.
RT Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling.
RL EMBO J. 21:2703-2714 (2002).
RN [4]; RE0024619.
RX PUBMED: 10747853.
RA Takeda K., Yasumoto K., Takada R., Takada S., Watanabe K., Udono T., Saito H., Takahashi K., Shibahara S.
RT Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a.
RL J. Biol. Chem. 275:14013-14016 (2000).
RN [5]; RE0070604.
RX PUBMED: 20363964.
RA Chen Q. Y., Zhang T., Pincus S. H., Wu S., Ricks D., Liu D., Sun Z., Maclaren N., Lan M. S.
RT Human CD1D gene expression is regulated by LEF-1 through distal promoter regulatory elements.
RL J. Immunol. 184:5047-5054 (2010).
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