TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T13873 XX ID T13873 XX DT 10.03.2005 (created); nvo. DT 09.09.2014 (updated); spk. CO Copyright (C), QIAGEN. XX FA MITF XX SY microphthalmia-associated transcription factor. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T10346 c-Fos; Mammalia. IN T09446 c-Jun; Mammalia. IN T15118 CBP; Mammalia. IN T10049 GABP-alpha; Mammalia. IN T10052 GABP-beta; Mammalia. IN T00403 Id1; mouse, Mus musculus. IN T10004 Id2; mouse, Mus musculus. IN T09198 Id3; mouse, Mus musculus. IN T16141 LEF-1; human, Homo sapiens. IN T13783 MafB; Mammalia. IN T18596 Otx2; Mammalia. IN T23091 p300; Mammalia. IN T10037 PU.1; Mammalia. IN T09538 Smad3; Mammalia. IN T17416 tfeb; Mammalia. IN T18332 TLS; mouse, Mus musculus. IN T00915 YY1; human, Homo sapiens. XX MX M01034 V$EBOX_Q6_01. MX M07050 V$MITF_Q4. MX M02099 V$MITF_Q6. MX M01029 V$TFE_Q6. XX BS R22871. BS R22872. BS R30051. BS R30052. BS R22975. BS R22945. BS R15438. BS R15440. BS R27387. BS R27388. BS R27390. BS R22971. BS R22968. BS R22969. BS R22970. BS R22957. BS R22953. BS R22997. BS R15374. BS R62671. BS R22972. BS R15422. BS R62857. BS R62858. BS R15424. XX DR TRANSPATH: MO000046905. DR TRANSCOMPEL: C00597. XX RN [1]; RE0016864. RX PUBMED: 10770922. RA Carreira S., Liu B., Goding C. R. RT The gene encoding the T-box factor Tbx2 is a target for the microphthalmia-associated transcription factor in melanocytes RL J. Biol. Chem. 275:21920-21927 (2000). RN [2]; RE0021075. RX PUBMED: 10673502. RA Wu M., Hemesath T. J., Takemoto C. M., Horstmann M. A., Wells A. G., Price E. R., Fisher D. Z., Fisher D. E. RT c-Kit triggers dual phosphorylations, which couple activation and degradation of the essential melanocyte factor Mi RL Genes Dev. 14:301-312 (2000). RN [3]; RE0021077. RX PUBMED: 9660747. RA Price E. R., Ding H. F., Badalian T., Bhattacharya S., Takemoto C., Yao T. P., Hemesath T. J., Fisher D. E. RT Lineage-specific signaling in melanocytes. C-kit stimulation recruits p300/CBP to microphthalmia RL J. Biol. Chem. 273:17983-17986 (1998). RN [4]; RE0024414. RX PUBMED: 11331755. RA Motyckova G., Weilbaecher K. N., Horstmann M., Rieman D. J., Fisher D. Z., Fisher D. E. RT Linking osteopetrosis and pycnodysostosis: regulation of cathepsin K expression by the microphthalmia transcription factor family. RL Proc. Natl. Acad. Sci. USA 98:5798-5803 (2001). RN [5]; RE0024466. RX PUBMED: 14527958. RA Funaba M., Ikeda T., Murakami M., Ogawa K., Tsuchida K., Sugino H., Abe M. RT Transcriptional activation of mouse mast cell Protease-7 by activin and transforming growth factor-beta is inhibited by microphthalmia-associated transcription factor. RL J. Biol. Chem. 278:52032-52041 (2003). RN [6]; RE0024475. RX PUBMED: 12032083. RA Yasumoto K., Takeda K., Saito H., Watanabe K., Takahashi K., Shibahara S. RT Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling. RL EMBO J. 21:2703-2714 (2002). RN [7]; RE0024476. RX PUBMED: 11709556. RA Levy C., Nechushtan H., Razin E. RT A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor. RL J. Biol. Chem. 277:1962-1966 (2002). RN [8]; RE0024478. RX PUBMED: 11157480. RA Ogihara H., Morii E., Kim D. K., Oboki K., Kitamura Y. RT Inhibitory effect of the transcription factor encoded by the mutant mi microphthalmia allele on transactivation of mouse mast cell protease 7 gene. RL Blood 97:645-651 (2001). RN [9]; RE0024922. RX PUBMED: 12663655. RA Martinez-Morales J. R., Dolez V., Rodrigo I., Zaccarini R., Leconte L., Bovolenta P., Saule S. RT OTX2 activates the molecular network underlying retina pigment epithelium differentiation. RL J. Biol. Chem. 278:21721-21731 (2003). RN [10]; RE0030581. RX PUBMED: 14583455. RA Chen D., Xu W., Bales E., Colmenares C., Conacci-Sorrell M., Ishii S., Stavnezer E., Campisi J., Fisher D. E., Ben-Ze'ev A., Medrano E. E. RT SKI activates Wnt/beta-catenin signaling in human melanoma. RL Cancer Res. 63:6626-34 (2003). RN [11]; RE0043874. RX PUBMED: 10361115. RA Kim D. K., Morii E., Ogihara H., Lee Y. M., Jippo T., Adachi S., Maeyama K., Kim H. M., Kitamura Y. RT Different effect of various mutant MITF encoded by mi, Mior, or Miwh allele on phenotype of murine mast cells RL Blood 93:4179-86 (1999). RN [12]; RE0044140. RX PUBMED: 12167402. RA Galy A., Neron B., Planque N., Saule S., Eychene A. RT Activated MAPK/ERK kinase (MEK-1) induces transdifferentiation of pigmented epithelium into neural retina RL Dev. Biol. 248:251-64 (2002). RN [13]; RE0044141. RX PUBMED: 15158462. RA Ito A., Koma Y., Watabe K., Jippo T., Wakayama T., Iseki S., Kitamura Y. RT Contribution of the SgIGSF adhesion molecule to survival of cultured mast cells in vivo RL Biochem. Biophys. Res. Commun. 319:200-6 (2004). RN [14]; RE0044142. RX PUBMED: 14975237. RA Lee Y. N., Nechushtan H., Figov N., Razin E. RT The function of lysyl-tRNA synthetase and Ap4A as signaling regulators of MITF activity in FcepsilonRI-activated mast cells RL Immunity 20:145-51 (2004). RN [15]; RE0044143. RX PUBMED: 9352446. RA Smith S. B., McClung J., Wiggert B. N., Nir I. RT Delayed rhodopsin regeneration and altered distribution of interphotoreceptor retinoid binding protein (IRBP) in the mi(vit)/mi(vit) (vitiligo) mouse RL J. Neurocytol. 26:605-13 (1997). RN [16]; RE0044171. RX PUBMED: 15254223. RA Vetrini F., Auricchio A., Du J., Angeletti B., Fisher D. E., Ballabio A., Marigo V. RT The microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesis RL Mol. Cell. Biol. 24:6550-9 (2004). RN [17]; RE0044172. RX PUBMED: 11700328. RA Du J., Fisher D. E. RT Identification of Aim-1 as the underwhite mouse mutant and its transcriptional regulation by MITF RL J. Biol. Chem. 277:402-6 (2002). RN [18]; RE0044187. RX PUBMED: 10694430. RA Xu W., Gong L., Haddad M. M., Bischof O., Campisi J., Yeh E. T., Medrano E. E. RT Regulation of microphthalmia-associated transcription factor MITF protein levels by association with the ubiquitin-conjugating enzyme hUBC9 RL Exp. Cell Res. 255:135-43 (2000). RN [19]; RE0044188. RX PUBMED: 14744763. RA Miller A. J., Du J., Rowan S., Hershey C. L., Widlund H. R., Fisher D. E. RT Transcriptional regulation of the melanoma prognostic marker melastatin (TRPM1) by MITF in melanocytes and melanoma RL Cancer Res. 64:509-16 (2004). RN [20]; RE0051632. RX PUBMED: 17371876. RA Beuret L., Flori E., Denoyelle C., Bille K., Busca R., Picardo M., Bertolotto C., Ballotti R. RT Up-regulation of MET expression by alpha-melanocyte-stimulating hormone and MITF allows hepatocyte growth factor to protect melanocytes and melanoma cells from apoptosis. RL J. Biol. Chem. 282:14140-14147 (2007). RN [21]; RE0056028. RX PUBMED: 19321441. RA Feng H., Cheng T., Steer J. H., Joyce D. A., Pavlos N. J., Leong C., Kular J., Liu J., Feng X., Zheng M. H., Xu J. RT MEF2 and MITF cooperate with NFATC1 to transactivate the V-ATPase D2 promoter during rankl-induced osteoclastogenesis. RL J. Biol. Chem. 284:14667-14676 (2009). XX //