AC T18332
XX
ID T18332
XX
DT 24.08.2006 (created); jag.
DT 03.01.2014 (updated); spk.
CO Copyright (C), QIAGEN.
XX
FA TLS
XX
SY D430004D17Rik; D930039C12Rik; FUS; FUS1; fusion, derived from t(12;16) malignant liposarcoma (human); Pigpen protein; RNA-binding protein FUS; TLS.
XX
OS mouse, Mus musculus
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; rodentia; myomorpha; muridae; murinae
XX
GE G037215 Fus.
XX
SF The TLS protein contains a transcriptional activation domain rich in glutamine residues (AD) (aa 1-165), three RGG domains (repeats of the tripeptide Arg-Gly-Gly) (aa 165-246, 372-425, and 454-526) and an 80-amino acid RNA recognition motif (RRM) (aa 287-372), both involved in the binding to RNA. [2];
XX
IN T09287 MITF-M; mouse, Mus musculus.
IN T01554 MITF; mouse, Mus musculus.
IN T13873 MITF; Mammalia.
IN T08317 PU.1-xbb1; mouse, Mus musculus.
IN T00702 PU.1; mouse, Mus musculus.
XX
BS R32612.
BS R32614.
BS R32616.
XX
DR TRANSPATH: MO000085572.
DR UniProtKB: P56959; FUS_MOUSE.
XX
RN [1]; RE0048819.
RX PUBMED: 16785428.
RA Bose R., Molina H., Patterson A. S., Bitok J. K., Periaswamy B., Bader J. S., Pandey A., Cole P. A.
RT Phosphoproteomic analysis of Her2/neu signaling and inhibition.
RL Proc. Natl. Acad. Sci. USA 103:9773-9778 (2006).
RN [2]; RE0048122.
RX PUBMED: 9478924.
RA Hallier M., Lerga A., Barnache S., Tavitian A., Moreau-Gachelin F.
RT The transcription factor Spi-1/PU.1 interacts with the potential splicing factor TLS.
RL J. Biol. Chem. 273:4838-4842 (1998).
XX
//