TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T18596 XX ID T18596 XX DT 10.03.2005 (created); nvo. DT 07.07.2015 (updated); hna. CO Copyright (C), QIAGEN. XX FA Otx2 XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T09404 HNF-3beta; Mammalia. IN T17992 Lim-1; Mammalia. IN T13873 MITF; Mammalia. XX MX M08892 V$CRX_Q6. MX M01387 V$OTX2_01. MX M01719 V$OTX2_Q3. MX M04623 V$OTX2_Q3_01. MX M01117 V$OTX_Q1. XX BS R36664. BS R33369. BS R33370. BS R35869. BS R67189. BS R68675. BS R16176. BS R33342. XX DR TRANSPATH: MO000046604. XX RN [1]; RE0024922. RX PUBMED: 12663655. RA Martinez-Morales J. R., Dolez V., Rodrigo I., Zaccarini R., Leconte L., Bovolenta P., Saule S. RT OTX2 activates the molecular network underlying retina pigment epithelium differentiation. RL J. Biol. Chem. 278:21721-21731 (2003). RN [2]; RE0025313. RX PUBMED: 10935548. RA Kelley C. G., Lavorgna G., Clark M. E., Boncinelli E., Mellon P. L. RT The Otx2 homeoprotein regulates expression from the gonadotropin-releasing hormone proximal promoter. RL Mol. Endocrinol. 14:1246-1256 (2000). RN [3]; RE0036366. RX PUBMED: 11412024. RA Kimura C., Shen M. M., Takeda N., Aizawa S., Matsuo I. RT Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast RL Dev. Biol. 235:12-32 (2001). RN [4]; RE0036989. RX PUBMED: 11731459. RA Martinez-Barbera J. P., Signore M., Boyl P. P., Puelles E., Acampora D., Gogoi R., Schubert F., Lumsden A., Simeone A. RT Regionalisation of anterior neuroectoderm and its competence in responding to forebrain and midbrain inducing activities depend on mutual antagonism between OTX2 and GBX2 RL Development 128:4789-800 (2001). RN [5]; RE0037068. RX PUBMED: 11124114. RA Liu A., Joyner A. L. RT EN and GBX2 play essential roles downstream of FGF8 in patterning the mouse mid/hindbrain region RL Development 128:181-191 (2001). RN [6]; RE0037688. RX PUBMED: 10564872. RA Gofflot F., Kolf-Clauw M., Clotman F., Roux C., Picard J. J. RT Absence of ventral cell populations in the developing brain in a rat model of the Smith-Lemli-Opitz syndrome RL Am. J. Med. Genet. 87:207-16 (1999). RN [7]; RE0037995. RX PUBMED: 11231064. RA Garda A. L., Echevarria D., Martinez S. RT Neuroepithelial co-expression of Gbx2 and Otx2 precedes Fgf8 expression in the isthmic organizer RL Mech. Dev. 101:111-8 (2001). RN [8]; RE0037997. RX PUBMED: 11704761. RA Ye W., Bouchard M., Stone D., Liu X., Vella F., Lee J., Nakamura H., Ang S. L., Busslinger M., Rosenthal A. RT Distinct regulators control the expression of the mid-hindbrain organizer signal FGF8 RL Nat. Neurosci. 4:1175-81 (2001). RN [9]; RE0038001. RX PUBMED: 10216227. RA Nguyen Ba-Charvet K. T., von Boxberg Y., Godement P. RT The mouse homeodomain protein OTX2 regulates NCAM promoter activity RL Mol. Brain Res. 67:292-5 (1999). RN [10]; RE0038002. RX PUBMED: 9753681. RA Ba-Charvet K. T., von Boxberg Y., Guazzi S., Boncinelli E., Godement P. RT A potential role for the OTX2 homeoprotein in creating early 'highways' for axon extension in the rostral brain RL Development 125:4273-82 (1998). RN [11]; RE0038015. RX PUBMED: 11291866. RA Jin O., Harpal K., Ang S. L., Rossant J. RT Otx2 and HNF3beta genetically interact in anterior patterning RL Int. J. Dev. Biol. 45:357-65 (2001). RN [12]; RE0038016. RX PUBMED: 12231626. RA Riccomagno M. M., Martinu L., Mulheisen M., Wu D. K., Epstein D. J. RT Specification of the mammalian cochlea is dependent on Sonic hedgehog RL Genes Dev. 16:2365-78 (2002). RN [13]; RE0038018. RX PUBMED: 8613727. RA Robel L., Ding M., James A. J., Lin X., Simeone A., Leckman J. F., Vaccarino F. M. RT Fibroblast growth factor 2 increases Otx2 expression in precursor cells from mammalian telencephalon RL J. Neurosci. 15:7879-91 (1995). XX //