AC T10346
XX
ID T10346
XX
DT 10.03.2005 (created); nvo.
DT 24.12.2015 (updated); hna.
CO Copyright (C), QIAGEN.
XX
FA c-Fos
XX
SY c-fos oncogene.
XX
OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
XX
IN T06598 AML-1; mouse, Mus musculus.
IN T14315 AML1; Mammalia.
IN T08443 AML3; mouse, Mus musculus.
IN T08796 ASC-2; human, Homo sapiens.
IN T17532 Bcl-3; Mammalia.
IN T09446 c-Jun; Mammalia.
IN T18005 c-MAF; Mammalia.
IN T11261 c-Rel; Mammalia.
IN T09410 C/EBPbeta; Mammalia.
IN T15118 CBP; Mammalia.
IN T23077 CHOP-10; Mammalia.
IN T30386 Fra-1; Mammalia.
IN T30385 Fra-2; Mammalia.
IN T08629 GATA-4; Mammalia.
IN T10446 GR; Mammalia.
IN T10510 JunB; Mammalia.
IN T09447 JunD; Mammalia.
IN T13783 MafB; Mammalia.
IN T13873 MITF; Mammalia.
IN T11025 NFATc1; Mammalia.
IN T11024 NFATc2; Mammalia.
IN T17367 NRL; Mammalia.
IN T23091 p300; Mammalia.
IN T10138 SF-1; Mammalia.
IN T30703 SIRT1; Mammalia.
IN T09538 Smad3; Mammalia.
IN T13998 Smad4; Mammalia.
IN T08326 Sp1; Mammalia.
IN T04632 SRC-1; human, Homo sapiens.
IN T08256 SRC-1A; human, Homo sapiens.
IN T22156 TSC22D3; Mammalia.
XX
MX M00172 V$AP1FJ_Q2.
MX M00517 V$AP1_01.
MX M00924 V$AP1_Q2_01.
MX M00926 V$AP1_Q4_01.
MX M00925 V$AP1_Q6_01.
MX M07600 V$CFOS_Q4.
MX M03815 V$CFOS_Q6.
XX
BS R61972.
BS R31024.
BS R31558.
BS R04079.
BS R24781.
BS R60089.
XX
DR TRANSPATH: MO000047855.
XX
RN [1]; RE0005630.
RX PUBMED: 7588605.
RA Bannister A. J., Kouzarides T.
RT CBP-induced stimulation of c-Fos activity is abrogated by E1A
RL EMBO J. 14:4758-4762 (1995).
RN [2]; RE0007192.
RX PUBMED: 8493100.
RA Ombra M. N., Autiero M., DeLerma Barbaro A., Barretta R., Del Pozzo G., Guardiola J.
RT Recognition of distinct HLA-DQA1 promoter elements by a single nuclear factor containing Jun and Fos or antigenically related proteins
RL Nucleic Acids Res. 21:1811- 1818 (1993).
RN [3]; RE0015392.
RX PUBMED: 10777532.
RA Lee S. K., Kim J. H., Lee Y. C., Cheong J., Lee J. W.
RT Silencing mediator of retinoic acid and thyroid hormone receptors, as a novel transcriptional corepressor molecule of activating protein-1, nuclear factor-kappaB, and serum response factor
RL J. Biol. Chem. 275:12470-12474 (2000).
RN [4]; RE0023220.
RX PUBMED: 11274169.
RA Hess J., Porte D., Munz C., Angel P.
RT AP-1 and Cbfa/runt physically interact and regulate parathyroid hormone-dependent MMP13 expression in osteoblasts through a new osteoblast-specific element 2/AP-1 composite element.
RL J. Biol. Chem. 276:20029-20038 (2001).
RN [5]; RE0024046.
RX PUBMED: 12385031.
RA Castellanos Mdel C., Lopez-Giral S., Lopez-Cabrera M., de Landazuri M. O.
RT Multiple cis-acting elements regulate the expression of the early T cell activation antigen CD69.
RL Eur. J. Immunol. 32:3108-3117 (2002).
RN [6]; RE0025071.
RX PUBMED: 10657527.
RA Yukimasa N., Isobe K., Nagai H., Takuwa Y., Nakai T.
RT Successive occupancy by immediate early transcriptional factors of the tyrosine hydroxylase gene TRE and CRE sites in PACAP-stimulated PC12 pheochromocytoma cells.
RL Neuropeptides 33:475-482 (1999).
RN [7]; RE0025403.
RX PUBMED: 11352916.
RA Takeuchi K., Shibamoto S., Nagamine K., Shigemori I., Omura S., Kitamura N., Ito F.
RT Signaling pathways leading to transcription and translation cooperatively regulate the transient increase in expression of c-Fos protein.
RL J. Biol. Chem. 276:26077-26083 (2001).
RN [8]; RE0026240.
RX PUBMED: 9187264.
RA Shayo C., Davio C., Brodsky A., Mladovan A. G., Legnazzi B. L., Rivera E., Baldi A.
RT Histamine modulates the expression of c-fos through cyclic AMP production via the H2 receptor in the human promonocytic cell line U937.
RL Mol. Pharmacol. 51:983-90 (1997).
RN [9]; RE0026567.
RX PUBMED: 10918580.
RA Finzer P., Soto U., Delius H., Patzelt A., Coy J. F., Poustka A., zur Hausen H., Rosl F.
RT Differential transcriptional regulation of the monocyte-chemoattractant protein-1 (MCP-1) gene in tumorigenic and non-tumorigenic HPV 18 positive cells: the role of the chromatin structure and AP-1 composition
RL Oncogene 19:3235-44 (2000).
RN [10]; RE0026716.
RX PUBMED: 10731717.
RA Zhuang D., Kawajiri H., Takahashi Y., Yoshimoto T.
RT Suppression of prostaglandin E(2)-mediated c-fos mRNA induction by interleukin-4 in murine macrophages.
RL J. Biochem. 127:451-6 (2000).
RN [11]; RE0027049.
RX PUBMED: 8264643.
RA Nakagawara A., Azar C. G., Scavarda N. J., Brodeur G. M.
RT Expression and function of TRK-B and BDNF in human neuroblastomas.
RL Mol. Cell. Biol. 14:759-67 (1994).
RN [12]; RE0027167.
RX PUBMED: 10716983.
RA Bruning J. C., Gillette J. A., Zhao Y., Bjorbaeck C., Kotzka J., Knebel B., Avci H., Hanstein B., Lingohr P., Moller D. E., Krone W., Kahn C. R., Muller-Wieland D.
RT Ribosomal subunit kinase-2 is required for growth factor-stimulated transcription of the c-Fos gene.
RL Proc. Natl. Acad. Sci. USA 97:2462-7 (2000).
RN [13]; RE0027787.
RX PUBMED: 10497212.
RA Na S. Y., Choi J. E., Kim H. J., Jhun B. H., Lee Y. C., Lee J. W.
RT Bcl3, an IkappaB protein, stimulates activating protein-1 transactivation and cellular proliferation.
RL J. Biol. Chem. 274:28491-6 (1999).
RN [14]; RE0027846.
RX PUBMED: 9989826.
RA Yokouchi M., Wakioka T., Sakamoto H., Yasukawa H., Ohtsuka S., Sasaki A., Ohtsubo M., Valius M., Inoue A., Komiya S., Yoshimura A.
RT APS, an adaptor protein containing PH and SH2 domains, is associated with the PDGF receptor and c-Cbl and inhibits PDGF-induced mitogenesis.
RL Oncogene 18:759-67 (1999).
RN [15]; RE0027868.
RX PUBMED: 11353786.
RA Hu Y. L., Tee M. K., Goetzl E. J., Auersperg N., Mills G. B., Ferrara N., Jaffe R. B.
RT Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells.
RL J. Natl. Cancer Inst. 93:762-7 (2001).
RN [16]; RE0028565.
RX PUBMED: 8946053.
RA Nonomura T., Kubo T., Oka T., Shimoke K., Yamada M., Enokido Y., Hatanaka H.
RT Signaling pathways and survival effects of BDNF and NT-3 on cultured cerebellar granule cells.
RL Brain Res. Dev. Brain Res. 97:42-50 (1996).
RN [17]; RE0029294.
RX PUBMED: 11698415.
RA Balasubramanian S., Efimova T., Eckert R. L.
RT Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes.
RL J. Biol. Chem. 277:1828-36 (2002).
RN [18]; RE0029406.
RX PUBMED: 11854297.
RA Lai C. F., Cheng S. L.
RT Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells.
RL J. Biol. Chem. 277:15514-22 (2002).
RN [19]; RE0029861.
RX PUBMED: 12239223.
RA Guo Y. S., Cheng J. Z., Jin G. F., Gutkind J. S., Hellmich M. R., Townsend C. M. Jr.
RT Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways. Evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor.
RL J. Biol. Chem. 277:48755-63 (2002).
RN [20]; RE0033095.
RX PUBMED: 14673133.
RA Manna P. R., Eubank D. W., Stocco D. M.
RT Assessment of the role of activator protein-1 on transcription of the mouse steroidogenic acute regulatory protein gene.
RL Mol. Endocrinol. 18:558-73 (2004).
RN [21]; RE0034367.
RX PUBMED: 11441089.
RA Li W., Whaley C. D., Bonnevier J. L., Mondino A., Martin M. E., Aagaard-Tillery K. M., Mueller D. L.
RT CD28 signaling augments Elk-1-dependent transcription at the c-fos gene during antigen stimulation.
RL J. Immunol. 167:827-35 (2001).
RN [22]; RE0035949.
RX PUBMED: 11875070.
RA Abe M. K., Saelzler M. P., Espinosa R 3. r. d., Kahle K. T., Hershenson M. B., Le Beau M. M., Rosner M. R.
RT ERK8, a new member of the mitogen-activated protein kinase family.
RL J. Biol. Chem. 277:16733-16743 (2002).
RN [23]; RE0035966.
RX PUBMED: 8710853.
RA Wang W., Chevray P. M., Nathans D.
RT Mammalian Sug1 and c-Fos in the nuclear 26S proteasome.
RL Proc. Natl. Acad. Sci. USA 93:8236-8240 (1996).
RN [24]; RE0035983.
RX PUBMED: 8617766.
RA Hermida-Matsumoto M. L., Chock P. B., Curran T., Yang D. C.
RT Ubiquitinylation of transcription factors c-Jun and c-Fos using reconstituted ubiquitinylating enzymes.
RL J. Biol. Chem. 271:4930-4936 (1996).
RN [25]; RE0036252.
RX PUBMED: 8823316.
RA Ko F. N., Yang Y. C., Huang S. C., Ou J. T.
RT Coagulation factor Xa stimulates platelet-derived growth factor release and mitogenesis in cultured vascular smooth muscle cells of rat
RL J. Clin. Invest. 98:1493-501 (1996).
RN [26]; RE0036829.
RX PUBMED: 9259411.
RA Kamohara H., Sakamoto K., Ishiko T., Masuda Y., Abe T., Ogawa M.
RT Leukemia inhibitory factor induces apoptosis and proliferation of human carcinoma cells through different oncogene pathways
RL Int. J. Cancer 72:687-95 (1997).
RN [27]; RE0037042.
RX PUBMED: 12481140.
RA Ruby N. F., Brennan T. J., Xie X., Cao V., Franken P., Heller H. C., O'Hara B. F.
RT Role of melanopsin in circadian responses to light
RL Science 298:2211-3 (2002).
RN [28]; RE0037045.
RX PUBMED: 12399428.
RA Ozaki Y., Onaka T., Nakazato M., Saito J., Kanemoto K., Matsumoto T., Ueta Y.
RT Centrally administered neuromedin U activates neurosecretion and induction of c-fos messenger ribonucleic acid in the paraventricular and supraoptic nuclei of rat
RL Endocrinology 143:4320-9 (2002).
RN [29]; RE0037334.
RX PUBMED: 11459819.
RA Matsumoto H., Noguchi J., Takatsu Y., Horikoshi Y., Kumano S., Ohtaki T., Kitada C., Itoh T., Onda H., Nishimura O., Fujino M.
RT Stimulation effect of galanin-like peptide (GALP) on luteinizing hormone-releasing hormone-mediated luteinizing hormone (LH) secretion in male rats
RL Endocrinology 142:3693-6 (2001).
RN [30]; RE0037610.
RX PUBMED: 14635186.
RA Shea C. M., Edgar C. M., Einhorn T. A., Gerstenfeld L. C.
RT BMP treatment of C3H10T1/2 mesenchymal stem cells induces both chondrogenesis and osteogenesis
RL J. Cell. Biochem. 90:1112-27 (2003).
RN [31]; RE0037628.
RX PUBMED: 14565925.
RA Okada S., Obata S., Hatano M., Tokuhisa T.
RT Dominant-negative effect of the c-fos family gene products on inducible NO synthase expression in macrophages
RL Int. Immunol. 15:1275-82 (2003).
RN [32]; RE0037798.
RX PUBMED: 9135069.
RA Felts S. J., Stang M. T., Getz M. J.
RT A c-Fos- and E1A-interacting component of the tissue factor basal promoter complex mediates synergistic activation of transcription by transforming growth factor-beta1
RL Oncogene 14:1679-85 (1997).
RN [33]; RE0037865.
RX PUBMED: 14632195.
RA Kanda N., Watanabe S.
RT 17Beta-estradiol enhances the production of nerve growth factor in THP-1-derived macrophages or peripheral blood monocyte-derived macrophages
RL J. Invest. Dermatol 121:771-80 (2003).
RN [34]; RE0037970.
RX PUBMED: 12914529.
RA Nandy A., Jenatschke S., Hartung B., Milde-Langosch K., Bamberger A. M., Gellersen B.
RT Genomic structure and transcriptional regulation of the human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene
RL J. Mol. Endocrinol. 31:105-21 (2003).
RN [35]; RE0038457.
RX PUBMED: 12667961.
RA Hattori Y., Matsumura M., Kasai K.
RT Vascular smooth muscle cell activation by C-reactive protein
RL Cardiovasc. Res. 58:186-95 (2003).
RN [36]; RE0038505.
RX PUBMED: 7519434.
RA Felley-Bosco E., Ambs S., Lowenstein C. J., Keefer L. K., Harris C. C.
RT Constitutive expression of inducible nitric oxide synthase in human bronchial epithelial cells induces c-fos and stimulates the cGMP pathway
RL Am. J. Respir. Cell Mol. Biol. 11:159-64 (1994).
RN [37]; RE0038686.
RX PUBMED: 9027324.
RA Nolan E. M., Cheung T. C., Burton D. W., Deftos L. J.
RT Transcriptional regulation of the human chromogranin A gene by its 5' distal regulatory element: novel effects of orientation, structure, flanking sequences, and position on expression
RL Mol. Cell. Endocrinol. 124:51-62 (1996).
RN [38]; RE0039515.
RX PUBMED: 1766667.
RA Abate C., Marshak D. R., Curran T.
RT Fos is phosphorylated by p34cdc2, cAMP-dependent protein kinase and protein kinase C at multiple sites clustered within regulatory regions
RL Oncogene 6:2179-85 (1991).
RN [39]; RE0039591.
RX PUBMED: 10799319.
RA Huang Y., Deng T., Winston B. W.
RT Characterization of hPRP4 kinase activation: potential role in signaling
RL Biochem. Biophys. Res. Commun. 271:456-63 (2000).
RN [40]; RE0039869.
RX PUBMED: 12177049.
RA Kannan-Thulasiraman P., Shapiro D. J.
RT Modulators of inflammation use nuclear factor-kappa B and activator protein-1 sites to induce the caspase-1 and granzyme B inhibitor, proteinase inhibitor 9
RL J. Biol. Chem. 277:41230-9 (2002).
RN [41]; RE0039885.
RX PUBMED: 11039902.
RA Sheng Z., Sun W., Smith E., Cohen C., Sheng Z., Xu X. X.
RT Restoration of positioning control following Disabled-2 expression in ovarian and breast tumor cells
RL Oncogene 19:4847-54 (2000).
RN [42]; RE0039886.
RX PUBMED: 11359772.
RA He J., Smith E. R., Xu X. X.
RT Disabled-2 exerts its tumor suppressor activity by uncoupling c-Fos expression and MAP kinase activation
RL J. Biol. Chem. 276:26814-8 (2001).
RN [43]; RE0040016.
RX PUBMED: 10449752.
RA Marconcini L., Marchio S., Morbidelli L., Cartocci E., Albini A., Ziche M., Bussolino F., Oliviero S.
RT c-fos-induced growth factor/vascular endothelial growth factor D induces angiogenesis in vivo and in vitro
RL Proc. Natl. Acad. Sci. USA 96:9671-6 (1999).
RN [44]; RE0040023.
RX PUBMED: 8036026.
RA Vara Prasad M. V., Shore S. K., Dhanasekaran N.
RT Activated mutant of G alpha 13 induces Egr-1, c-fos, and transformation in NIH 3T3 cells
RL Oncogene 9:2425-9 (1994).
RN [45]; RE0040414.
RX PUBMED: 9610372.
RA Kawata A., Mikuni-Takagaki Y.
RT Mechanotransduction in stretched osteocytes--temporal expression of immediate early and other genes
RL Biochem. Biophys. Res. Commun. 246:404-8 (1998).
RN [46]; RE0040415.
RX PUBMED: 12239115.
RA Demiralp B., Chen H. L., Koh A. J., Keller E. T., McCauley L. K.
RT Anabolic actions of parathyroid hormone during bone growth are dependent on c-fos
RL Endocrinology 143:4038-47 (2002).
RN [47]; RE0040733.
RX PUBMED: 10657480.
RA Redburn J. L., Leah J. D.
RT The induction and potentiation of c-Jun and c-Fos expression in spinal neurons mediated by NK1 and NK2 receptors
RL Neuropeptides 33:115-9 (1999).
RN [48]; RE0041086.
RX PUBMED: 9513047.
RA Tsygankova O. M., Peng M., Maloney J. A., Hopkins N., Williamson J. R.
RT Angiotensin II induces diverse signal transduction pathways via both Gq and Gi proteins in liver epithelial cells
RL J. Cell. Biochem. 69:63-71 (1998).
RN [49]; RE0041366.
RX PUBMED: 9001250.
RA Lamb R. F., Hennigan R. F., Turnbull K., Katsanakis K. D., MacKenzie E. D., Birnie G. D., Ozanne B. W.
RT AP-1-mediated invasion requires increased expression of the hyaluronan receptor CD44
RL Mol. Cell. Biol. 17:963-76 (1997).
RN [50]; RE0041478.
RX PUBMED: 8891291.
RA Honore P., Buritova J., Besson J. M.
RT The effects of morphine on carrageenin-induced spinal c-Fos expression are completely blocked by beta-funaltrexamine, a selective mu-opioid receptor antagonist
RL Brain Res. 732:242-6 (1996).
RN [51]; RE0041611.
RX PUBMED: 9651224.
RA Bitner R. S., Nikkel A. L., Curzon P., Arneric S. P., Bannon A. W., Decker M. W.
RT Role of the nucleus raphe magnus in antinociception produced by ABT-594: immediate early gene responses possibly linked to neuronal nicotinic acetylcholine receptors on serotonergic neurons
RL J. Neurosci. 18:5426-32 (1998).
RN [52]; RE0041692.
RX PUBMED: 10713736.
RA Preston G. A., Srinivasan D., Barrett J. C.
RT Apoptotic response to growth factor deprivation involves cooperative interactions between c-Fos and p300
RL Cell Death Differ. 7:215-26 (2000).
RN [53]; RE0041735.
RX PUBMED: 12590600.
RA Schwindt T. T., Forti F. L., Juliano M. A., Juliano L., Armelin H. A.
RT Arginine vasopressin inhibition of cyclin D1 gene expression blocks the cell cycle and cell proliferation in the mouse Y1 adrenocortical tumor cell line
RL Biochemistry 42:2116-21 (2003).
RN [54]; RE0041765.
RX PUBMED: 12618529.
RA Faccio R., Takeshita S., Zallone A., Ross F. P., Teitelbaum S. L.
RT c-Fms and the alphavbeta3 integrin collaborate during osteoclast differentiation
RL J. Clin. Invest. 111:749-58 (2003).
RN [55]; RE0041784.
RX PUBMED: 12622723.
RA Terasawa K., Okazaki K., Nishida E.
RT Regulation of c-Fos and Fra-1 by the MEK5-ERK5 pathway
RL Genes Cells 8:263-73 (2003).
RN [56]; RE0042023.
RX PUBMED: 15056714.
RA Zhang L., Lou D., Jiao H., Zhang D., Wang X., Xia Y., Zhang J., Xu M.
RT Cocaine-induced intracellular signaling and gene expression are oppositely regulated by the dopamine D1 and D3 receptors
RL J. Neurosci. 24:3344-54 (2004).
RN [57]; RE0042112.
RX PUBMED: 11446746.
RA Fernandez S., Knopf M. A., Bjork S. K., McGillis J. P.
RT Bone marrow-derived macrophages express functional CGRP receptors and respond to CGRP by increasing transcription of c-fos and IL-6 mRNA
RL Cell. Immunol. 209:140-8 (2001).
RN [58]; RE0042144.
RX PUBMED: 9517481.
RA Marz P., Herget T., Lang E., Otten U., Rose-John S.
RT Activation of gp130 by IL-6/soluble IL-6 receptor induces neuronal differentiation
RL Eur. J. Neurosci. 9:2765-73 (1997).
RN [59]; RE0042168.
RX PUBMED: 7824266.
RA Seetharam L., Gotoh N., Maru Y., Neufeld G., Yamaguchi S., Shibuya M.
RT A unique signal transduction from FLT tyrosine kinase, a receptor for vascular endothelial growth factor VEGF
RL Oncogene 10:135-47 (1995).
RN [60]; RE0042201.
RX PUBMED: 10973597.
RA Olszewski P. K., Grace M. K., Billington C. J., Levine A. S.
RT The effect of [Phe(1)psi(CH(2)-NH)Gly(2)]-nociceptin(1-13)NH(2) on feeding and c-Fos immunoreactivity in selected brain sites
RL Brain Res. 876:95-102 (2000).
RN [61]; RE0042389.
RX PUBMED: 9580241.
RA Castellanos M. C., Munoz C., Montoya M. C., Lara-Pezzi E., Lopez-Cabrera M., de Landazuri M. O.
RT Expression of the leukocyte early activation antigen CD69 is regulated by the transcription factor AP-1
RL J. Immunol. 159:5463-73 (1997).
RN [62]; RE0042405.
RX PUBMED: 12598637.
RA Campbell R. E., Smith M. S., Allen S. E., Grayson B. E., Ffrench-Mullen J. M., Grove K. L.
RT Orexin neurons express a functional pancreatic polypeptide Y4 receptor
RL J. Neurosci. 23:1487-97 (2003).
RN [63]; RE0042469.
RX PUBMED: 9064320.
RA Trotta R., Kanakaraj P., Perussia B.
RT Fc gamma R-dependent mitogen-activated protein kinase activation in leukocytes: a common signal transduction event necessary for expression of TNF-alpha and early activation genes
RL J. Exp. Med. 184:1027-35 (1996).
RN [64]; RE0042486.
RX PUBMED: 12441106.
RA Zhang S., Liu J., MacGibbon G., Dragunow M., Cooper G. J.
RT Increased expression and activation of c-Jun contributes to human amylin-induced apoptosis in pancreatic islet beta-cells
RL J. Mol. Biol. 324:271-85 (2002).
RN [65]; RE0042501.
RX PUBMED: 15194005.
RA Kim J. I., Jo E. J., Lee H. Y., Kang H. K., Lee Y. N., Kwak J. Y., Bae Y. S.
RT Stimulation of early gene induction and cell proliferation by lysophosphatidic acid in human amnion-derived WISH cells: role of phospholipase D-mediated pathway
RL Biochem. Pharmacol. 68:333-40 (2004).
RN [66]; RE0042692.
RX PUBMED: 12464353.
RA Tsubokou Y., Kobayashi N., Mita S., Yoshida K., Matsuoka H.
RT Celiprolol inhibits mitogen-activated protein kinase and endothelin-1 and transforming growth factor-beta(1) gene in rats
RL Eur. J. Pharmacol. 457:85-93 (2002).
RN [67]; RE0042888.
RX PUBMED: 9500466.
RA Sapi E., Flick M. B., Rodov S., Kacinski B. M.
RT Ets-2 transdominant mutant abolishes anchorage-independent growth and macrophage colony-stimulating factor-stimulated invasion by BT20 breast carcinoma cells
RL Cancer Res. 58:1027-33 (1998).
RN [68]; RE0043213.
RX PUBMED: 9203564.
RA Panegyres P. K., Hughes J.
RT Activation of c-fos mRNA in the brain by the kappa-opioid receptor agonist enadoline and the NMDA receptor antagonist dizocilpine
RL Eur. J. Pharmacol. 328:31-6 (1997).
RN [69]; RE0043214.
RX PUBMED: 12721110.
RA Laorden M. L., Castells M. T., Milanes M. V.
RT Effects of U-50,488H and U-50,488H withdrawal on c-fos expression in the rat paraventricular nucleus. Correlation with c-fos in brainstem catecholaminergic neurons
RL Br. J. Pharmacol. 138:1544-52 (2003).
RN [70]; RE0043663.
RX PUBMED: 10585578.
RA Itakura J., Ishiwata T., Shen B., Kornmann M., Korc M.
RT Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer
RL Int. J. Cancer 85:27-34 (2000).
RN [71]; RE0043769.
RX PUBMED: 8114760.
RA Kimura E., Sonobe M. H., Armelin M. C., Armelin H. A.
RT Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives
RL Mol. Endocrinol. 7:1463-71 (1993).
RN [72]; RE0043774.
RX PUBMED: 8188692.
RA Sakurai T., Abe Y., Kasuya Y., Takuwa N., Shiba R., Yamashita T., Endo T., Goto K.
RT Activin A stimulates mitogenesis in Swiss 3T3 fibroblasts without activation of mitogen-activated protein kinases
RL J. Biol. Chem. 269:14118-22 (1994).
RN [73]; RE0043828.
RX PUBMED: 1382409.
RA Tripathi Y. B., Lim R. W., Fernandez-Gallardo S., Kandala J. C., Guntaka R. V., Shukla S. D.
RT Involvement of tyrosine kinase and protein kinase C in platelet- activating-factor-induced c-fos gene expression in A-431 cells
RL Biochem. J. 286:527-33 (1992).
RN [74]; RE0044553.
RX PUBMED: 12151802.
RA Wirth M. M., Olszewski P. K., Levine A. S., Giraudo S. Q.
RT Effect of Agouti-related protein on development of conditioned taste aversion and oxytocin neuronal activation
RL Neuroreport 13:1355-8 (2002).
RN [75]; RE0044576.
RX PUBMED: 12221085.
RA Li X., Massa P. E., Hanidu A., Peet G. W., Aro P., Savitt A., Mische S., Li J., Marcu K. B.
RT IKKalpha, IKKbeta, and NEMO/IKKgamma are each required for the NF-kappa B-mediated inflammatory response program
RL J. Biol. Chem. 277:45129-40 (2002).
RN [76]; RE0044655.
RX PUBMED: 11817901.
RA Hilgenberg L. G., Ho K. D., Lee D., O'Dowd D. K., Smith M. A.
RT Agrin regulates neuronal responses to excitatory neurotransmitters in vitro and in vivo
RL Mol. Cell. Neurosci. 19:97-110 (2002).
RN [77]; RE0044656.
RX PUBMED: 10460245.
RA Hilgenberg L. G., Hoover C. L., Smith M. A.
RT Evidence of an agrin receptor in cortical neurons
RL J. Neurosci. 19:7384-93 (1999).
RN [78]; RE0044868.
RX PUBMED: 8544984.
RA Moorman J. M., Jackson A., Grahame-Smith D. G., Leslie R. A.
RT Induction of c-fos in rat forebrain by pharmacological manipulation of 5-hydroxytryptamine levels
RL Neuroscience 68:1089-96 (1995).
RN [79]; RE0044873.
RX PUBMED: 8798649.
RA Jang S. I., Steinert P. M., Markova N. G.
RT Activator protein 1 activity is involved in the regulation of the cell type-specific expression from the proximal promoter of the human profilaggrin gene
RL J. Biol. Chem. 271:24105-14 (1996).
RN [80]; RE0044892.
RX PUBMED: 10804201.
RA Figiel M., Engele J.
RT Pituitary adenylate cyclase-activating polypeptide (PACAP), a neuron-derived peptide regulating glial glutamate transport and metabolism
RL J. Neurosci. 20:3596-605 (2000).
RN [81]; RE0045049.
RX PUBMED: 12112414.
RA Yatin S. M., Miller G. M., Norton C., Madras B. K.
RT Dopamine transporter-dependent induction of C-Fos in HEK cells
RL Synapse 45:52-65 (2002).
RN [82]; RE0045303.
RX PUBMED: 15086567.
RA Gangnuss S., Cowin A. J., Daehn I. S., Hatzirodos N., Rothnagel J. A., Varelias A., Rayner T. E.
RT Regulation of MAPK activation, AP-1 transcription factor expression and keratinocyte differentiation in wounded fetal skin.
RL J. Invest. Dermatol 122:791-804 (2004).
RN [83]; RE0045304.
RX PUBMED: 14673150.
RA Murphy L. O., MacKeigan J. P., Blenis J.
RT A network of immediate early gene products propagates subtle differences in mitogen-activated protein kinase signal amplitude and duration
RL Mol. Cell. Biol. 24:144-53 (2004).
RN [84]; RE0045331.
RX PUBMED: 8816391.
RA Maroder M., Bellavia D., Meco D., Napolitano M., Stigliano A., Alesse E., Vacca A., Giannini G., Frati L., Gulino A., Screpanti I.
RT Expression of trKB neurotrophin receptor during T cell development. Role of brain derived neurotrophic factor in immature thymocyte survival
RL J. Immunol. 157:2864-72 (1996).
RN [85]; RE0045389.
RX PUBMED: 10487857.
RA Kelley K. A., Ho L., Winger D., Freire-Moar J., Borelli C. B., Aisen P. S., Pasinetti G. M.
RT Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2
RL Am. J. Pathol. 155:995-1004 (1999).
RN [86]; RE0045673.
RX PUBMED: 10816578.
RA Ng D. C., Shafaee S., Lee D., Bikle D. D.
RT Requirement of an AP-1 site in the calcium response region of the involucrin promoter
RL J. Biol. Chem. 275:24080-8 (2000).
RN [87]; RE0045740.
RX PUBMED: 7532277.
RA Graus-Porta D., Beerli R. R., Hynes N. E.
RT Single-chain antibody-mediated intracellular retention of ErbB-2 impairs Neu differentiation factor and epidermal growth factor signaling
RL Mol. Cell. Biol. 15:1182-91 (1995).
RN [88]; RE0045833.
RX PUBMED: 9435201.
RA Hammond D. L., Wang H., Nakashima N., Basbaum A. I.
RT Differential effects of intrathecally administered delta and mu opioid receptor agonists on formalin-evoked nociception and on the expression of Fos-like immunoreactivity in the spinal cord of the rat
RL J. Pharmacol. Exp. Ther. 284:378-87 (1998).
RN [89]; RE0045859.
RX PUBMED: 9854051.
RA Lane S. J., Adcock I. M., Richards D., Hawrylowicz C., Barnes P. J., Lee T. H.
RT Corticosteroid-resistant bronchial asthma is associated with increased c-fos expression in monocytes and T lymphocytes
RL J. Clin. Invest. 102:2156-64 (1998).
RN [90]; RE0046495.
RX PUBMED: 9605760.
RA Hishiki T., Nimura Y., Isogai E., Kondo K., Ichimiya S., Nakamura Y., Ozaki T., Sakiyama S., Hirose M., Seki N., Takahashi H., Ohnuma N., Tanabe M., Nakagawara A.
RT Glial cell line-derived neurotrophic factor/neurturin-induced differentiation and its enhancement by retinoic acid in primary human neuroblastomas expressing c-Ret, GFR alpha-1, and GFR alpha-2
RL Cancer Res. 58:2158-65 (1998).
RN [91]; RE0046559.
RX PUBMED: 11397794.
RA Mittelstadt P. R., Ashwell J. D.
RT Inhibition of AP-1 by the glucocorticoid-inducible protein GILZ
RL J. Biol. Chem. 276:29603-10 (2001).
RN [92]; RE0047040.
RX PUBMED: 15087382.
RA Brellier F., Marionnet C., Chevallier-Lagente O., Toftgard R., Mauviel A., Sarasin A., Magnaldo T.
RT Ultraviolet irradiation represses PATCHED gene transcription in human epidermal keratinocytes through an activator protein-1-dependent process
RL Cancer Res. 64:2699-704 (2004).
RN [93]; RE0047363.
RX PUBMED: 9642216.
RA Lee S. K., Kim H. J., Na S. Y., Kim T. S., Choi H. S., Im S. Y., Lee J. W.
RT Steroid receptor coactivator-1 coactivates activating protein-1-mediated transactivations through interaction with the c-Jun and c-Fos subunits.
RL J. Biol. Chem. 273:16651-16654 (1998).
RN [94]; RE0047533.
RX PUBMED: 10523647.
RA Ubeda M., Vallejo M., Habener J. F.
RT CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins.
RL Mol. Cell. Biol. 19:7589-7599 (1999).
RN [95]; RE0047851.
RX PUBMED: 10847592.
RA Lee S. K., Na S. Y., Jung S. Y., Choi J. E., Jhun B. H., Cheong J., Meltzer P. S., Lee Y. C., Lee J. W.
RT Activating protein-1, nuclear factor-kappaB, and serum response factor as novel target molecules of the cancer-amplified transcription coactivator ASC-2.
RL Mol. Endocrinol. 14:915-925 (2000).
RN [96]; RE0047941.
RX PUBMED: 8387155.
RA Kroll D. J., Sullivan D. M., Gutierrez-Hartmann A., Hoeffler J. P.
RT Modification of DNA topoisomerase II activity via direct interactions with the cyclic adenosine-3',5'-monophosphate response element-binding protein and related transcription factors.
RL Mol. Endocrinol. 7:305-318 (1993).
RN [97]; RE0048088.
RX PUBMED: 8945519.
RA Kallunki T., Deng T., Hibi M., Karin M.
RT c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions.
RL Cell 87:929-939 (1996).
RN [98]; RE0054705.
RX PUBMED: 18342022.
RA Tapias A., Ciudad C. J., Noe V.
RT Transcriptional regulation of the 5'-flanking region of the human transcription factor Sp3 gene by NF-1, c-Myb, B-Myb, AP-1 and E2F.
RL Biochim. Biophys. Acta 1779:318-329 (2008).
RN [99]; RE0055798.
RX PUBMED: 19164283.
RA Gao S. Y., Li E. M., Cui L., Lu X. F., Meng L. Y., Yuan H. M., Xie J. J., Du Z. P., Pang J. X., Xu L. Y.
RT Sp1 and AP-1 regulate expression of the human gene VIL2 in esophageal carcinoma cells.
RL J. Biol. Chem. 284:7995-8004 (2009).
RN [100]; RE0066089.
RX PUBMED: 20042607.
RA Zhang R., Chen H. Z., Liu J. J., Jia Y. Y., Zhang Z. Q., Yang R. F., Zhang Y., Xu J., Wei Y. S., Liu D. P., Liang C. C.
RT SIRT1 Suppresses Activator Protein-1 Transcriptional Activity and Cyclooxygenase-2 Expression in Macrophages.
RL J. Biol. Chem. 285:7097-7110 (2010).
RN [101]; RE0070412.
RX PUBMED: 20498278.
RA Adler J., Reuven N., Kahana C., Shaul Y.
RT c-Fos proteasomal degradation is activated by a default mechanism, and its regulation by NAD(P)H:quinone oxidoreductase 1 determines c-Fos serum response kinetics.
RL Mol. Cell. Biol. 30:3767-3778 (2010).
XX
//