TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10510 XX ID T10510 XX DT 10.03.2005 (created); nvo. DT 04.07.2016 (updated); ros. CO Copyright (C), QIAGEN. XX FA JunB XX SY jun B proto-oncogene; Jun-b; MyD21; TRANSCRIPTION FACTOR JUN-B. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T16043 BCL-6; Mammalia. IN T04074 brca1; human, Homo sapiens. IN T15204 brca1; Mammalia. IN T10346 c-Fos; Mammalia. IN T09446 c-Jun; Mammalia. IN T00261 ER-alpha; human, Homo sapiens. IN T30386 Fra-1; Mammalia. IN T30385 Fra-2; Mammalia. IN T09354 Hex; mouse, Mus musculus. IN T06578 jdp2; rat, Rattus norvegicus. IN T09447 JunD; Mammalia. IN T23091 p300; Mammalia. IN T09538 Smad3; Mammalia. IN T13998 Smad4; Mammalia. IN T14175 TBP; Mammalia. XX MX M00517 V$AP1_01. MX M00924 V$AP1_Q2_01. MX M00926 V$AP1_Q4_01. MX M00925 V$AP1_Q6_01. MX M03551 V$JUNB_Q6. XX BS R62491. BS R62492. BS R21386. BS R24701. BS R73907. XX DR TRANSPATH: MO000046957. DR TRANSCOMPEL: C00079. DR TRANSCOMPEL: C00080. DR TRANSCOMPEL: C00195. XX RN [1]; RE0004737. RX PUBMED: 1945831. RA Suzuki T., Okuno H., Yoshida T., Endo T., Nishina H., Iba H. RT Difference in transcriptional regulatory function between c-Fos and Fra-2 RL Nucleic Acids Res. 19:5537-5542 (1991). RN [2]; RE0004865. RX PUBMED: 1406676. RA Kovary K., Bravo R. RT Existence of different Fos/Jun complexes during the G0-to-G1 transition and during exponential growth in mouse fibroblasts: differential role of Fos proteins RL Mol. Cell. Biol. 12:5015-5023 (1992). RN [3]; RE0011961. RX PUBMED: 7759510. RA Welter J. F., Crish J. F., Agarwal C., Eckert R. L. RT Fos-related antigen (Fra-1), junB, and junD activate human involucrin promoter transcription by binding to proximal and distal AP1 sites to mediate phorbol ester effects on promoter activity RL J. Biol. Chem. 270:12614-12622 (1995). RN [4]; RE0016410. RX PUBMED: 10485843. RA Luo K., Stroschein S. L., Wang W., Chen D., Martens E., Zhou S., Zhou Q. RT The Ski oncoprotein interacts with the Smad proteins to repress TGFbeta signaling. RL Genes Dev. 13:2196-2206 (1999). RN [5]; RE0018232. RX PUBMED: 8754832. RA Lee J. S., See R. H., Deng T., Shi Y. RT Adenovirus E1A downregulates cJun- and JunB-mediated transcription by targeting their coactivator p300. RL Mol. Cell. Biol. 16:4312-4326 (1996). RN [6]; RE0023952. RX PUBMED: 10903323. RA Verrecchia F., Pessah M., Atfi A., Mauviel A. RT Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation. RL J. Biol. Chem. 275:30226-30231 (2000). RN [7]; RE0025071. RX PUBMED: 10657527. RA Yukimasa N., Isobe K., Nagai H., Takuwa Y., Nakai T. RT Successive occupancy by immediate early transcriptional factors of the tyrosine hydroxylase gene TRE and CRE sites in PACAP-stimulated PC12 pheochromocytoma cells. RL Neuropeptides 33:475-482 (1999). RN [8]; RE0028124. RX PUBMED: 9889198. RA Li B., Tournier C., Davis R. J., Flavell R. A. RT Regulation of IL-4 expression by the transcription factor JunB during T helper cell differentiation. RL EMBO J. 18:420-32 (1999). RN [9]; RE0029294. RX PUBMED: 11698415. RA Balasubramanian S., Efimova T., Eckert R. L. RT Green tea polyphenol stimulates a Ras, MEKK1, MEK3, and p38 cascade to increase activator protein 1 factor-dependent involucrin gene expression in normal human keratinocytes. RL J. Biol. Chem. 277:1828-36 (2002). RN [10]; RE0029406. RX PUBMED: 11854297. RA Lai C. F., Cheng S. L. RT Signal transductions induced by bone morphogenetic protein-2 and transforming growth factor-beta in normal human osteoblastic cells. RL J. Biol. Chem. 277:15514-22 (2002). RN [11]; RE0030228. RX PUBMED: 12522006. RA Liu H., Keefer J. R., Wang Q. F., Friedman A. D. RT Reciprocal effects of C/EBPalpha and PKCdelta on JunB expression and monocytic differentiation depend upon the C/EBPalpha basic region. RL Blood 101:3885-92 (2003). RN [12]; RE0031549. RX PUBMED: 11477071. RA Teyssier C., Belguise K., Galtier F., Chalbos D. RT Characterization of the physical interaction between estrogen receptor alpha and JUN proteins. RL J. Biol. Chem. 276:36361-9 (2001). RN [13]; RE0032069. RX PUBMED: 7848298. RA Franklin C. C., McCulloch A. V., Kraft A. S. RT In vitro association between the Jun protein family and the general transcription factors, TBP and TFIIB. RL Biochem. J. 305:967-74 (1995). RN [14]; RE0032082. RX PUBMED: 11841562. RA Jha N., Kumar M. J., Boonplueang R., Andersen J. K. RT Glutathione decreases in dopaminergic PC12 cells interfere with the ubiquitin protein degradation pathway: relevance for Parkinson's disease? RL J. Neurochem 80:555-61 (2002). RN [15]; RE0036829. RX PUBMED: 9259411. RA Kamohara H., Sakamoto K., Ishiko T., Masuda Y., Abe T., Ogawa M. RT Leukemia inhibitory factor induces apoptosis and proliferation of human carcinoma cells through different oncogene pathways RL Int. J. Cancer 72:687-95 (1997). RN [16]; RE0039765. RX PUBMED: 9405416. RA Fuchs S. Y., Xie B., Adler V., Fried V. A., Davis R. J., Ronai Z. RT c-Jun NH2-terminal kinases target the ubiquitination of their associated transcription factors RL J. Biol. Chem. 272:32163-8 (1997). RN [17]; RE0039777. RX PUBMED: 10683516. RA Wang H. Y., Jiang X. M., Ganea D. RT The neuropeptides VIP and PACAP inhibit IL-2 transcription by decreasing c-Jun and increasing JunB expression in T cells RL J. Neuroimmunol. 104:68-78 (2000). RN [18]; RE0039895. RX PUBMED: 14570911. RA Coss D., Jacobs S. B., Bender C. E., Mellon P. L. RT A novel AP-1 site is critical for maximal induction of the follicle-stimulating hormone beta gene by gonadotropin-releasing hormone RL J. Biol. Chem. 279:152-62 (2004). RN [19]; RE0039898. RX PUBMED: 14769860. RA Kenner L., Hoebertz A., Beil T., Keon N., Karreth F., Eferl R., Scheuch H., Szremska A., Amling M., Schorpp-Kistner M., Angel P., Wagner E. F. RT Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects RL J. Cell Biol. 164:613-23 (2004). RN [20]; RE0041564. RX PUBMED: 8793851. RA Autelitano D. J., Cohen D. R. RT CRF stimulates expression of multiple fos and jun related genes in the AtT-20 corticotroph cell RL Mol. Cell. Endocrinol. 119:25-35 (1996). RN [21]; RE0041565. RX PUBMED: 10618645. RA Zhang M., Miller C., He Y., Martel-Pelletier J., Pelletier J. P., Di Battista J. A. RT Calphostin C induces AP1 synthesis and AP1-dependent c-jun transactivation in normal human chondrocytes independent of protein kinase C-alpha inhibition: possible role for c-jun N-terminal kinase RL J. Cell. Biochem. 76:290-302 (1999). RN [22]; RE0043323. RX PUBMED: 15187104. RA Voice J., Donnelly S., Dorsam G., Dolganov G., Paul S., Goetzl E. J. RT c-Maf and JunB mediation of Th2 differentiation induced by the type 2 G protein-coupled receptor (VPAC2) for vasoactive intestinal peptide RL J. Immunol. 172:7289-96 (2004). RN [23]; RE0043769. RX PUBMED: 8114760. RA Kimura E., Sonobe M. H., Armelin M. C., Armelin H. A. RT Induction of FOS and JUN proteins by adrenocorticotropin and phorbol ester but not by 3',5'-cyclic adenosine monophosphate derivatives RL Mol. Endocrinol. 7:1463-71 (1993). RN [24]; RE0046985. RX PUBMED: 15358865. RA Gao M., Labuda T., Xia Y., Gallagher E., Fang D., Liu Y. C., Karin M. RT Jun turnover is controlled through JNK-dependent phosphorylation of the E3 ligase Itch RL Science 306:271-5 (2004). RN [25]; RE0047040. RX PUBMED: 15087382. RA Brellier F., Marionnet C., Chevallier-Lagente O., Toftgard R., Mauviel A., Sarasin A., Magnaldo T. RT Ultraviolet irradiation represses PATCHED gene transcription in human epidermal keratinocytes through an activator protein-1-dependent process RL Cancer Res. 64:2699-704 (2004). RN [26]; RE0048037. RX PUBMED: 12080089. RA Hu Y. F., Li R. RT JunB potentiates function of BRCA1 activation domain 1 (AD1) through a coiled-coil-mediated interaction. RL Genes Dev. 16:1509-1517 (2002). RN [27]; RE0048039. RX PUBMED: 12052834. RA Yazgan O., Pfarr C. M. RT Regulation of two JunD isoforms by Jun N-terminal kinases. RL J. Biol. Chem. 277:29710-29718 (2002). RN [28]; RE0048088. RX PUBMED: 8945519. RA Kallunki T., Deng T., Hibi M., Karin M. RT c-Jun can recruit JNK to phosphorylate dimerization partners via specific docking interactions. RL Cell 87:929-939 (1996). RN [29]; RE0048805. RX PUBMED: 15308641. RA Narayanan K., Srinivas R., Peterson M. C., Ramachandran A., Hao J., Thimmapaya B., Scherer P. E., George A. RT Transcriptional regulation of dentin matrix protein 1 by JunB and p300 during osteoblast differentiation. RL J. Biol. Chem. 279:44294-44302 (2004). RN [30]; RE0052694. RX PUBMED: 11551904. RA Schaefer L. K., Wang S., Schaefer T. S. RT Functional interaction of Jun and homeodomain proteins. RL J. Biol. Chem. 276:43074-43082 (2001). XX //