TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T14175 XX ID T14175 XX DT 10.03.2005 (created); nvo. DT 10.06.2014 (updated); hna. CO Copyright (C), QIAGEN. XX FA TBP XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T18749 Ahr-xbb2; human, Homo sapiens. IN T08910 Bcl-3; human, Homo sapiens. IN T09446 c-Jun; Mammalia. IN T14435 c-Myc; Mammalia. IN T11261 c-Rel; Mammalia. IN T08664 C/EBPalpha; Mammalia. IN T23087 C2TA; Mammalia. IN T15118 CBP; Mammalia. IN T10784 CtBP1; Mammalia. IN T09570 E2F-1; Mammalia. IN T17905 Gli2; Mammalia. IN T10446 GR; Mammalia. IN T16474 HMGB1; Mammalia. IN T14490 hnRNPK; Mammalia. IN T15348 Ikaros; Mammalia. IN T10510 JunB; Mammalia. IN T09447 JunD; Mammalia. IN T30592 Msx-1; Mammalia. IN T23091 p300; Mammalia. IN T10279 Pax-3; Mammalia. IN T10303 Pax-5; Mammalia. IN T13888 pax6; Mammalia. IN T08628 POU2F1; Mammalia. IN T25008 pRb; Mammalia. IN T10037 PU.1; Mammalia. IN T10429 PU.1; mouse, Mus musculus. IN T10397 RelA-p65; Mammalia. IN T10469 REST; Mammalia. IN T08433 RXR-alpha; human, Homo sapiens. IN T08326 Sp1; Mammalia. IN T09269 Spi-B-isoform1; human, Homo sapiens. IN T08256 SRC-1A; human, Homo sapiens. IN T17039 TEF-1; Mammalia. IN T10512 TFIIA-alpha/beta precursor; Mammalia. IN T17428 TFIIB; Mammalia. IN T09133 YY1; Mammalia. IN T10308 ZNF76-isoform1; human, Homo sapiens. IN T19572 ZNF76-isoform2; human, Homo sapiens. XX MX M00252 V$TATA_01. MX M00216 V$TATA_C. MX M00471 V$TBP_01. MX M00980 V$TBP_Q6. MX M03581 V$TBP_Q6_01. XX BS R26482. BS R30345. BS R61411. BS R62311. BS R23542. BS R31671. BS R26480. BS R31670. BS R33361. BS R57257. XX DR TRANSPATH: MO000046346. XX RN [1]; RE0004220. RX PUBMED: 8202368. RA Zwilling S., Annweiler A., Wirth T. RT The POU domains of the Oct1 and Oct2 transcription factors mediate specific interaction with TBP RL Nucleic Acids Res. 22:1655-1662 (1994). RN [2]; RE0004888. RX PUBMED: 8070410. RA Metz R., Kouzarides T., Bravo R. RT A C-terminal domain in FosB, absent in FosB/SF and Fra-1, which is able to interact with the TATA binding protein, is required for altered cell growth RL EMBO J. 13:3832-3842 (1994). RN [3]; RE0005594. RX PUBMED: 8663456. RA Hoffmann A., Roeder R. G. RT Cloning and characterization of human TAF20/15: Multiple interactions suggest a central role in TFIID complex formation RL J. Biol. Chem. 271:18194-18202 (1996). RN [4]; RE0006144. RX PUBMED: 9311784. RA Dantonel J. C., Murthy K. G. K., Manley J. L., Tora L. RT Transcription factor TFIID recruits factor CPSF for formation of 3� end of mRNA RL Nature 389:399-402 (1997). RN [5]; RE0006836. RX PUBMED: 8657158. RA Malik S., Karathanasis S. K. RT TFIIB-directed transcriptional activation by the Orphan nuclear receptor hepatocyte nuclear factor 4 RL Mol. Cell. Biol. 16:1824-1831 (1996). RN [6]; RE0009292. RX PUBMED: 8006019. RA Ge H., Roeder R. G. RT The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein RL J. Biol. Chem. 269:17136-17140 (1994). RN [7]; RE0009859. RX PUBMED: 7935440. RA Kim Y. W., Otterson G. A., Kratzke R. A., Coxon A. B., Kaye F. J. RT Differential specificity for binding of retinoblastoma binding protein 2 to RB, p107, and TATA-binding protein RL Mol. Cell. Biol. 14:7256-7264 (1994). RN [8]; RE0010799. RX PUBMED: 7667283. RA Schulman I. G., Chakravarti D., Juguilon H., Romo A., Evans R. M. RT Interactions between the retinoid X receptor and a conserved region of the TATA-binding protein mediate hormone-dependent transactivation RL Proc. Natl. Acad. Sci. USA 92:8288-8292 (1995). RN [9]; RE0012275. RX PUBMED: 8628302. RA Michelotti E. F., Michelotti G. A., Aronsohn A. I., Levens D. RT Heterogenous nuclear ribonucleoprotein K is a transcriptional factor RL Mol. Cell. Biol. 16:2350-2360 (1996). RN [10]; RE0014899. RX PUBMED: 10373544. RA Hsieh Y. J., Wang Z., Kovelman R., Roeder R. G. RT Cloning and characterization of two evolutionarily conserved subunits (TFIIIC102 and TFIIIC63) of human TFIIIC and their involvement in functional interactions with TFIIIB and RNA polymerase III RL Mol. Cell. Biol. 19:4944-4952 (1999). RN [11]; RE0015991. RX PUBMED: 11121026. RA Teichmann M., Wang Z., Roeder R. G. RT A stable complex of a novel transcription factor IIB- related factor, human TFIIIB50, and associated proteins mediate selective transcription by RNA polymerase III of genes with upstream promoter elements. RL Proc. Natl. Acad. Sci. USA 97:14200-14205 (2000). RN [12]; RE0017031. RX PUBMED: 10648625. RA Oda T., Kayukawa K., Hagiwara H., Yudate H. T., Masuho Y., Murakami Y., Tamura T. A., Muramatsu M. A. RT A novel TATA-binding protein-binding protein, ABT1, activates basal transcription and has a yeast homolog that is essential for growth. RL Mol. Cell. Biol. 20:1407-1418 (2000). RN [13]; RE0021242. RX PUBMED: 8502484. RA Abraham S. E., Lobo S., Yaciuk P., Wang H. G., Moran E. RT p300, and p300-associated proteins, are components of TATA-binding protein (TBP) complexes RL Oncogene 8:1639-1647 (1993). RN [14]; RE0022568. RX PUBMED: 9177216. RA Mahanta S. K., Scholl T., Yang F. C., Strominger J. L. RT Transactivation by CIITA, the type II bare lymphocyte syndrome-associated factor, requires participation of multiple regions of the TATA box binding protein. RL Proc. Natl. Acad. Sci. USA 94:6324-6329 (1997). RN [15]; RE0024034. RX PUBMED: 11313476. RA Kim L. J., Seto A. G., Nguyen T. N., Goodrich J. A. RT Human Taf(II)130 is a coactivator for NFATp. RL Mol. Cell. Biol. 21:3503-3513 (2001). RN [16]; RE0028100. RX PUBMED: 11316804. RA Lively T. N., Ferguson H. A., Galasinski S. K., Seto A. G., Goodrich J. A. RT c-Jun binds the N terminus of human TAF(II)250 to derepress RNA polymerase II transcription in vitro. RL J. Biol. Chem. 276:25582-8 (2001). RN [17]; RE0029739. RX PUBMED: 12217962. RA Wang P. J., Page D. C. RT Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis. RL Hum. Mol. Genet. 11:2341-6 (2002). RN [18]; RE0032026. RX PUBMED: 11959865. RA Koipally J., Georgopoulos K. RT Ikaros-CtIP interactions do not require C-terminal binding protein and participate in a deacetylase-independent mode of repression. RL J. Biol. Chem. 277:23143-9 (2002). RN [19]; RE0032069. RX PUBMED: 7848298. RA Franklin C. C., McCulloch A. V., Kraft A. S. RT In vitro association between the Jun protein family and the general transcription factors, TBP and TFIIB. RL Biochem. J. 305:967-74 (1995). RN [20]; RE0034939. RX PUBMED: 8761475. RA Kim R. H., Li J. J., Ogata Y., Yamauchi M., Freedman L. P., Sodek J. RT Identification of a vitamin D3-response element that overlaps a unique inverted TATA box in the rat bone sialoprotein gene. RL Biochem. J. 318:219-26 (1996). RN [21]; RE0036500. RX PUBMED: 11564744. RA Cabart P., Murphy S. RT BRFU, a TFIIB-like Factor, Is Directly Recruited to the TATA-box of Polymerase III Small Nuclear RNA Gene Promoters through Its Interaction with TATA-binding Protein RL J. Biol. Chem. 276:43056-64 (2001). RN [22]; RE0036545. RX PUBMED: 12621023. RA Hinkley C. S., Hirsch H. A., Gu L., LaMere B., Henry R. W. RT The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition RL J. Biol. Chem. 278:18649-57 (2003). RN [23]; RE0037355. RX PUBMED: 12665565. RA Pointud J. C., Mengus G., Brancorsini S., Monaco L., Parvinen M., Sassone-Corsi P., Davidson I. RT The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation RL J. Cell Sci. 116:1847-58 (2003). RN [24]; RE0037356. RX PUBMED: 11438666. RA Gangloff Y. G., Pointud J. C., Thuault S., Carre L., Romier C., Muratoglu S., Brand M., Tora L., Couderc J. L., Davidson I. RT The TFIID components human TAF(II)140 and Drosophila BIP2 (TAF(II)155) are novel metazoan homologues of yeast TAF(II)47 containing a histone fold and a PHD finger RL Mol. Cell. Biol. 21:5109-21 (2001). RN [25]; RE0037523. RX PUBMED: 9989412. RA Ryu S., Zhou S., Ladurner A. G., Tjian R. RT The transcriptional cofactor complex CRSP is required for activity of the enhancer-binding protein Sp1 RL Nature 397:446-50 (1999). RN [26]; RE0039168. RX PUBMED: 14580349. RA Guermah M., Ge K., Chiang C. M., Roeder R. G. RT The TBN protein, which is essential for early embryonic mouse development, is an inducible TAFII implicated in adipogenesis RL Mol. Cell 12:991-1001 (2003). RN [27]; RE0041095. RX PUBMED: 9710587. RA Veal E., Eisenstein M., Tseng Z. H., Gill G. RT A cellular repressor of E1A-stimulated genes that inhibits activation by E2F RL Mol. Cell. Biol. 18:5032-41 (1998). RN [28]; RE0042506. RX PUBMED: 15225551. RA Schaffar G., Breuer P., Boteva R., Behrends C., Tzvetkov N., Strippel N., Sakahira H., Siegers K., Hayer-Hartl M., Hartl F. U. RT Cellular toxicity of polyglutamine expansion proteins: mechanism of transcription factor deactivation RL Mol. Cell 15:95-105 (2004). RN [29]; RE0042804. RX PUBMED: 10454579. RA Kim H. J., Yi J. Y., Sung H. S., Moore D. D., Jhun B. H., Lee Y. C., Lee J. W. RT Activating signal cointegrator 1, a novel transcription coactivator of nuclear receptors, and its cytosolic localization under conditions of serum deprivation RL Mol. Cell. Biol. 19:6323-32 (1999). RN [30]; RE0043608. RX PUBMED: 9372915. RA Wang H. D., Trivedi A., Johnson D. L. RT Hepatitis B virus X protein induces RNA polymerase III-dependent gene transcription and increases cellular TATA-binding protein by activating the Ras signaling pathway RL Mol. Cell. Biol. 17:6838-46 (1997). RN [31]; RE0043934. RX PUBMED: 9288944. RA Chibazakura T., Watanabe F., Kitajima S., Tsukada K., Yasukochi Y., Teraoka H. RT Phosphorylation of human general transcription factors TATA-binding protein and transcription factor IIB by DNA-dependent protein kinase--synergistic stimulation of RNA polymerase II basal transcription in vitro RL Eur. J. Biochem. 247:1166-73 (1997). RN [32]; RE0045405. RX PUBMED: 14645237. RA Fang X., Han H., Stamatoyannopoulos G., Li Q. RT Developmentally specific role of the CCAAT box in regulation of human gamma-globin gene expression RL J. Biol. Chem. 279:5444-9 (2004). RN [33]; RE0045657. RX PUBMED: 10816571. RA Mariotti M., De Benedictis L., Avon E., Maier J. A. RT Interaction between endothelial differentiation-related factor-1 and calmodulin in vitro and in vivo RL J. Biol. Chem. 275:24047-51 (2000). RN [34]; RE0046306. RX PUBMED: 10921893. RA McCulloch V., Hardin P., Peng W., Ruppert J. M., Lobo-Ruppert S. M. RT Alternatively spliced hBRF variants function at different RNA polymerase III promoters RL EMBO J. 19:4134-43 (2000). RN [35]; RE0046399. RX PUBMED: 11058964. RA Wang Y. C., Huang C. F., Tung S. F., Lin Y. S. RT Competition with TATA box-binding protein for binding to the TATA box implicated in human cytomegalovirus IE2-mediated transcriptional repression of cellular promoters RL DNA Cell Biol. 19:613-9 (2000). RN [36]; RE0046515. RX PUBMED: 10471789. RA Yoshida T., Makino Y., Tamura T. RT Association of the rat heterogeneous nuclear RNA-ribonucleoprotein F with TATA-binding protein RL FEBS Lett. 457:251-4 (1999). RN [37]; RE0046518. RX PUBMED: 14592981. RA Fairley J. A., Scott P. H., White R. J. RT TFIIIB is phosphorylated, disrupted and selectively released from tRNA promoters during mitosis in vivo RL EMBO J. 22:5841-50 (2003). RN [38]; RE0046520. RX PUBMED: 10567391. RA Kabe Y., Goto M., Shima D., Imai T., Wada T., Morohashi K., Shirakawa M., Hirose S., Handa H. RT The role of human MBF1 as a transcriptional coactivator RL J. Biol. Chem. 274:34196-202 (1999). RN [39]; RE0046523. RX PUBMED: 15197246. RA Murai K., Naruse Y., Shaul Y., Agata Y., Mori N. RT Direct interaction of NRSF with TBP: chromatin reorganization and core promoter repression for neuron-specific gene transcription RL Nucleic Acids Res. 32:3180-9 (2004). RN [40]; RE0046528. RX PUBMED: 8621623. RA Jiang S. W., Eberhardt N. L. RT TEF-1 transrepression in BeWo cells is mediated through interactions with the TATA-binding protein, TBP RL J. Biol. Chem. 271:9510-8 (1996). RN [41]; RE0046529. RX PUBMED: 8051080. RA Coulombe B., Li J., Greenblatt J. RT Topological localization of the human transcription factors IIA, IIB, TATA box-binding protein, and RNA polymerase II-associated protein 30 on a class II promoter RL J. Biol. Chem. 269:19962-7 (1994). RN [42]; RE0046546. RX PUBMED: 12411709. RA Martianov I., Viville S., Davidson I. RT RNA polymerase II transcription in murine cells lacking the TATA binding protein RL Science 298:1036-9 (2002). RN [43]; RE0046548. RX PUBMED: 11457828. RA Wu S. Y., Chiang C. M. RT TATA-binding protein-associated factors enhance the recruitment of RNA polymerase II by transcriptional activators RL J. Biol. Chem. 276:34235-43 (2001). RN [44]; RE0047680. RX PUBMED: 9812988. RA Na S. Y., Choi H. S., Kim J. W., Na D. S., Lee J. W. RT Bcl3, an IkappaB protein, as a novel transcription coactivator of the retinoid X receptor. RL J. Biol. Chem. 273:30933-30938 (1998). RN [45]; RE0047682. RX PUBMED: 12040021. RA Brendel C., Gelman L., Auwerx J. RT Multiprotein bridging factor-1 (MBF-1) is a cofactor for nuclear receptors that regulate lipid metabolism. RL Mol. Endocrinol. 16:1367-1377 (2002). RN [46]; RE0048134. RX PUBMED: 10196196. RA Rao S., Matsumura A., Yoon J., Simon M. C. RT SPI-B activates transcription via a unique proline, serine, and threonine domain and exhibits DNA binding affinity differences from PU.1. RL J. Biol. Chem. 274:11115-11124 (1999). RN [47]; RE0048222. RX PUBMED: 11160734. RA Browning C. M., Smith M. J., Clark N. M., Lane B. R., Parada C., Montano M., KewalRamani V. N., Littman D. R., Essex M., Roeder R. G., Markovitz D. M. RT Human GLI-2 is a tat activation response element-independent Tat cofactor. RL J. Virol. 75:2314-2323 (2001). RN [48]; RE0048297. RX PUBMED: 10359315. RA Cvekl A., Kashanchi F., Brady J. N., Piatigorsky J. RT Pax-6 interactions with TATA-box-binding protein and retinoblastoma protein. RL Invest. Ophthalmol. Vis. Sci. 40:1343-1350 (1999). RN [49]; RE0050020. RX PUBMED: 16337145. RA Zheng G., Yang Y. C. RT Acetylation and alternative splicing regulate ZNF76-mediated transcription. RL Biochem. Biophys. Res. Commun. 339:1069-1075 (2006). XX //