TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10303 XX ID T10303 XX DT 10.03.2005 (created); nvo. DT 13.01.2015 (updated); hna. CO Copyright (C), QIAGEN. XX FA Pax-5 XX SY B-cell specific activator protein; BSAP; BSAP/PAX-5, B-cell Specific Activating Protein; Pax-5; PAX5. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T14315 AML1; Mammalia. IN T10873 c-Ets-1; Mammalia. IN T17679 c-Myb; Mammalia. IN T15977 COE1; Mammalia. IN T08470 Daxx-isoform1; human, Homo sapiens. IN T10531 Egr-1; Mammalia. IN T10516 HIF-1alpha; Mammalia. IN T09551 LEF-1; Mammalia. IN T16719 Net; Mammalia. IN T25008 pRb; Mammalia. IN T10037 PU.1; Mammalia. IN T14175 TBP; Mammalia. XX MX M00143 V$PAX5_01. MX M00144 V$PAX5_02. MX M03577 V$PAX5_Q6. MX M00808 V$PAX_Q6. XX BS R65717. BS R65718. BS R41906. BS R26817. BS R33069. BS R33070. BS R33072. BS R19752. XX DR TRANSPATH: MO000048068. XX RN [1]; RE0025783. RX PUBMED: 14594818. RA Merluzzi S., Moretti M., Altamura S., Zwollo P., Sigvardsson M., Vitale G., Pucillo C. RT CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism. RL J. Biol. Chem. 279:1777-86 (2004). RN [2]; RE0027532. RX PUBMED: 10688639. RA Maitra S., Atchison M. RT BSAP can repress enhancer activity by targeting PU.1 function. RL Mol. Cell. Biol. 20:1911-22 (2000). RN [3]; RE0032107. RX PUBMED: 9079818. RA Tian J., Okabe T., Miyazaki T., Takeshita S., Kudo A. RT Pax-5 is identical to EBB-1/KLP and binds to the VpreB and lambda5 promoters as well as the KI and KII sites upstream of the Jkappa genes. RL Eur. J. Immunol. 27:750-5 (1997). RN [4]; RE0035360. RX PUBMED: 12052884. RA Lin K. I., Angelin-Duclos C., Kuo T. C., Calame K. RT Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells. RL Mol. Cell. Biol. 22:4771-4780 (2002). RN [5]; RE0040984. RX PUBMED: 9545244. RA Nutt S. L., Morrison A. M., Dorfler P., Rolink A., Busslinger M. RT Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments RL EMBO J. 17:2319-33 (1998). RN [6]; RE0042428. RX PUBMED: 11799127. RA Emelyanov A. V., Kovac C. R., Sepulveda M. A., Birshtein B. K. RT The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells RL J. Biol. Chem. 277:11156-64 (2002). XX //