AC T10303
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ID T10303
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DT 10.03.2005 (created); nvo.
DT 13.01.2015 (updated); hna.
CO Copyright (C), QIAGEN.
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FA Pax-5
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SY B-cell specific activator protein; BSAP; BSAP/PAX-5, B-cell Specific Activating Protein; Pax-5; PAX5.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T14315 AML1; Mammalia.
IN T10873 c-Ets-1; Mammalia.
IN T17679 c-Myb; Mammalia.
IN T15977 COE1; Mammalia.
IN T08470 Daxx-isoform1; human, Homo sapiens.
IN T10531 Egr-1; Mammalia.
IN T10516 HIF-1alpha; Mammalia.
IN T09551 LEF-1; Mammalia.
IN T16719 Net; Mammalia.
IN T25008 pRb; Mammalia.
IN T10037 PU.1; Mammalia.
IN T14175 TBP; Mammalia.
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MX M00143 V$PAX5_01.
MX M00144 V$PAX5_02.
MX M03577 V$PAX5_Q6.
MX M00808 V$PAX_Q6.
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BS R65717.
BS R65718.
BS R41906.
BS R26817.
BS R33069.
BS R33070.
BS R33072.
BS R19752.
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DR TRANSPATH: MO000048068.
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RN [1]; RE0025783.
RX PUBMED: 14594818.
RA Merluzzi S., Moretti M., Altamura S., Zwollo P., Sigvardsson M., Vitale G., Pucillo C.
RT CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism.
RL J. Biol. Chem. 279:1777-86 (2004).
RN [2]; RE0027532.
RX PUBMED: 10688639.
RA Maitra S., Atchison M.
RT BSAP can repress enhancer activity by targeting PU.1 function.
RL Mol. Cell. Biol. 20:1911-22 (2000).
RN [3]; RE0032107.
RX PUBMED: 9079818.
RA Tian J., Okabe T., Miyazaki T., Takeshita S., Kudo A.
RT Pax-5 is identical to EBB-1/KLP and binds to the VpreB and lambda5 promoters as well as the KI and KII sites upstream of the Jkappa genes.
RL Eur. J. Immunol. 27:750-5 (1997).
RN [4]; RE0035360.
RX PUBMED: 12052884.
RA Lin K. I., Angelin-Duclos C., Kuo T. C., Calame K.
RT Blimp-1-dependent repression of Pax-5 is required for differentiation of B cells to immunoglobulin M-secreting plasma cells.
RL Mol. Cell. Biol. 22:4771-4780 (2002).
RN [5]; RE0040984.
RX PUBMED: 9545244.
RA Nutt S. L., Morrison A. M., Dorfler P., Rolink A., Busslinger M.
RT Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments
RL EMBO J. 17:2319-33 (1998).
RN [6]; RE0042428.
RX PUBMED: 11799127.
RA Emelyanov A. V., Kovac C. R., Sepulveda M. A., Birshtein B. K.
RT The interaction of Pax5 (BSAP) with Daxx can result in transcriptional activation in B cells
RL J. Biol. Chem. 277:11156-64 (2002).
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