TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10873 XX ID T10873 XX DT 10.03.2005 (created); nvo. DT 09.09.2015 (updated); smt. CO Copyright (C), QIAGEN. XX FA c-Ets-1 XX SY c-Ets-1; C-ets-1 protein; p54. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T09212 c-MAF; mouse, Mus musculus. IN T10201 COUP-TF1; Mammalia. IN T21852 HDAC1; Mammalia. IN T15683 HIF2A; Mammalia. IN T09278 IRF-4-isoform1; mouse, Mus musculus. IN T01945 NFATc1; human, Homo sapiens. IN T23091 p300; Mammalia. IN T10303 Pax-5; Mammalia. IN T22434 Prox-1-isoform1; human, Homo sapiens. IN T08326 Sp1; Mammalia. IN T10807 USF; Mammalia. XX MX M00032 V$CETS1P54_01. MX M00074 V$CETS1P54_02. MX M01078 V$CETS1P54_03. MX M01870 V$CETS1_Q6. MX M00339 V$ETS1_B. MX M08881 V$ETSLIKE_Q4. MX M00340 V$ETS_B. MX M00771 V$ETS_Q4. MX M00971 V$ETS_Q6. XX BS R26589. BS R73988. BS R37706. BS R69663. BS R26367. BS R05034. BS R25595. BS R28164. BS R73945. BS R26594. BS R26595. BS R61372. BS R18147. BS R31008. BS R72393. BS R23151. BS R71869. BS R33313. BS R26320. BS R12088. BS R24836. BS R14156. BS R40232. BS R25841. BS R36061. BS R72386. BS R22329. BS R09810. BS R58389. BS R72398. BS R67554. BS R25776. BS R36051. BS R61881. BS R33074. BS R33076. BS R26372. BS R61443. BS R61440. BS R64450. BS R64451. BS R64452. BS R64453. BS R64454. BS R64455. BS R64456. BS R64457. BS R64458. BS R25788. BS R65860. BS R04065. BS R26155. BS R72369. BS R60656. BS R61626. BS R18141. BS R18145. BS R36065. BS R61435. BS R36354. BS R74015. BS R02924. BS R32706. BS R73873. XX DR TRANSPATH: MO000047064. DR TRANSCOMPEL: C00007. DR TRANSCOMPEL: C00021. DR TRANSCOMPEL: C00082. DR TRANSCOMPEL: C00083. DR TRANSCOMPEL: C00084. DR TRANSCOMPEL: C00085. DR TRANSCOMPEL: C00170. DR TRANSCOMPEL: C00173. DR TRANSCOMPEL: C00235. DR TRANSCOMPEL: C00262. DR TRANSCOMPEL: C00271. DR TRANSCOMPEL: C00274. DR TRANSCOMPEL: C00359. DR TRANSCOMPEL: C00524. DR TRANSCOMPEL: C00553. DR TRANSCOMPEL: C00572. XX RN [1]; RE0006054. RX PUBMED: 9106660. RA Mayall T. P., Sheridan P. L., Montminy M. R., Jones K. A. RT Distinct roles for P-CREB and LEF-1 in TCRalpha enhancer assembly and activation on chromatin templates in vitro RL Genes Dev. 11:887-899 (1997). RN [2]; RE0010245. RX PUBMED: 7798271. RA Villena J. A., Martin I., Vinas O., Cormand B., Iglesias R., Mampel T., Giralt M., Villarroya F. RT Ets transcription factors regulate the expression of the gene for the human mitochondrial ATP synthase beta - subunit RL J. Biol. Chem. 269:32649-32654 (1994). RN [3]; RE0016555. RX PUBMED: 9551977. RA Perkel J. M., Atchison M. L. RT A two-step mechanism for recruitment of Pip by PU.1 RL J. Immunol. 160:241-252 (1998). RN [4]; RE0016681. RX PUBMED: 9501094. RA Sieweke M. H., Tekotte H., Jarosch U., Graf T. RT Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells. RL EMBO J. 17:1728-1739 (1998). RN [5]; RE0023729. RX PUBMED: 12464608. RA Elvert G., Kappel A., Heidenreich R., Englmeier U., Lanz S., Acker T., Rauter M., Plate K., Sieweke M., Breier G., Flamme I. RT Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1). RL J. Biol. Chem. 278:7520-7530 (2003). RN [6]; RE0023824. RX PUBMED: 11779502. RA Garvie C. W., Hagman J., Wolberger C. RT Structural studies of Ets-1/Pax5 complex formation on DNA. RL Mol. Cell 8:1267-1276 (2001). RN [7]; RE0025773. RX PUBMED: 12048211. RA Dwivedi P. P., Hii C. S., Ferrante A., Tan J., Der C. J., Omdahl J. L., Morris H. A., May B. K. RT Role of MAP kinases in the 1,25-dihydroxyvitamin D3-induced transactivation of the rat cytochrome P450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5. RL J. Biol. Chem. 277:29643-53 (2002). RN [8]; RE0029605. RX PUBMED: 10048576. RA Oda N., Abe M., Sato Y. RT ETS-1 converts endothelial cells to the angiogenic phenotype by inducing the expression of matrix metalloproteinases and integrin beta3. RL J. Cell. Physiol. 178:121-32 (1999). RN [9]; RE0033402. RX PUBMED: 10429657. RA Tanaka K., Abe M., Sato Y. RT Roles of extracellular signal-regulated kinase 1/2 and p38 mitogen-activated protein kinase in the signal transduction of basic fibroblast growth factor in endothelial cells during angiogenesis. RL Jpn. J. Cancer Res. 90:647-54 (1999). RN [10]; RE0035363. RX PUBMED: 10749681. RA Zhang W., Revers L., Pierce M., Schachter H. RT Regulation of expression of the human beta-1,2-N-acetylglucosaminyltransferase II gene (MGAT2) by Ets transcription factors. RL Biochem. J. 347:511-518 (2000). RN [11]; RE0035591. RX PUBMED: 10358095. RA Jayaraman G., Srinivas R., Duggan C., Ferreira E., Swaminathan S., Somasundaram K., Williams J., Hauser C., Kurkinen M., Dhar R., Weitzman S., Buttice G., Thimmapaya B. RT p300/cAMP-responsive element-binding protein interactions with ets-1 and ets-2 in the transcriptional activation of the human stromelysin promoter. RL J. Biol. Chem. 274:17342-17352 (1999). RN [12]; RE0036631. RX PUBMED: 12752447. RA Liu M., Leibowitz J. L., Clark D. A., Mendicino M., Ning Q., Ding J. W., D'Abreo C., Fung L., Marsden P. A., Levy G. A. RT Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 RL Eur. J. Biochem. 270:2274-86 (2003). RN [13]; RE0037965. RX PUBMED: 10650939. RA Greenland K. J., Jantke I., Jenatschke S., Bracken K. E., Vinson C., Gellersen B. RT The human NAD+-dependent 15-hydroxyprostaglandin dehydrogenase gene promoter is controlled by Ets and activating protein-1 transcription factors and progesterone RL Endocrinology 141:581-97 (2000). RN [14]; RE0038630. RX PUBMED: 15087126. RA Feng Y., Goulet A. C., Nelson M. A. RT Identification and characterization of the human Cdc2l2 gene promoter RL Gene 330:75-84 (2004). RN [15]; RE0039436. RX PUBMED: 11234019. RA Ohtani N., Zebedee Z., Huot T. J., Stinson J. A., Sugimoto M., Ohashi Y., Sharrocks A. D., Peters G., Hara E. RT Opposing effects of Ets and Id proteins on p16INK4a expression during cellular senescence RL Nature 409:1067-70 (2001). RN [16]; RE0041005. RX PUBMED: 10049588. RA Williams M., Lyu M. S., Yang Y. L., Lin E. P., Dunbrack R., Birren B., Cunningham J., Hunter K. RT Ier5, a novel member of the slow-kinetics immediate-early genes RL Genomics 55:327-34 (1999). RN [17]; RE0041861. RX PUBMED: 15001984. RA Jinnin M., Ihn H., Asano Y., Yamane K., Trojanowska M., Tamaki K. RT Tenascin-C upregulation by transforming growth factor-beta in human dermal fibroblasts involves Smad3, Sp1, and Ets1 RL Oncogene 23:1656-67 (2004). RN [18]; RE0042220. RX PUBMED: 12642588. RA Sugimoto H., Sugimoto S., Tatei K., Obinata H., Bakovic M., Izumi T., Vance D. E. RT Identification of Ets-1 as an important transcriptional activator of CTP:phosphocholine cytidylyltransferase alpha in COS-7 cells and co-activation with transcriptional enhancer factor-4 RL J. Biol. Chem. 278:19716-22 (2003). RN [19]; RE0043465. RX PUBMED: 10751370. RA Arbiser J. L., Larsson H., Claesson-Welsh L., Bai X., LaMontagne K., Weiss S. W., Soker S., Flynn E., Brown L. F. RT Overexpression of VEGF 121 in immortalized endothelial cells causes conversion to slowly growing angiosarcoma and high level expression of the VEGF receptors VEGFR-1 and VEGFR-2 in vivo RL Am. J. Pathol. 156:1469-76 (2000). RN [20]; RE0043711. RX PUBMED: 14534532. RA Duda D. G., Sunamura M., Lefter L. P., Furukawa T., Yokoyama T., Yatsuoka T., Abe T., Inoue H., Motoi F., Egawa S., Matsuno S., Horii A. RT Restoration of SMAD4 by gene therapy reverses the invasive phenotype in pancreatic adenocarcinoma cells RL Oncogene 22:6857-64 (2003). RN [21]; RE0044518. RX PUBMED: 12145208. RA Xu D., Wilson T. J., Chan D., De Luca E., Zhou J., Hertzog P. J., Kola I. RT Ets1 is required for p53 transcriptional activity in UV-induced apoptosis in embryonic stem cells RL EMBO J. 21:4081-93 (2002). RN [22]; RE0045622. RX PUBMED: 12095690. RA Masumoto N., Chen J., Sirotnak F. M. RT Regulation of transcription of the murine gamma-glutamyl hydrolase gene. Delineation of core promoter A and the role of LYF-1, E2F and ETS-1 in determining tumor-specific expression RL Gene 291:169-76 (2002). RN [23]; RE0045705. RX PUBMED: 12119294. RA Hadri L., Ozog A., Soncin F., Lompre A. M. RT Basal transcription of the mouse sarco(endo)plasmic reticulum Ca2+-ATPase type 3 gene in endothelial cells is controlled by Ets-1 and Sp1 RL J. Biol. Chem. 277:36471-8 (2002). RN [24]; RE0048003. RX PUBMED: 9566892. RA Hedge S. P., Kumar A., Kurschner C., Shapiro L. H. RT c-Maf interacts with c-Myb to regulate transcription of an early myeloid gene during differentiation. RL Mol. Cell. Biol. 18:2729-2737 (1998). RN [25]; RE0048258. RX PUBMED: 12743594. RA Pei H., Yordy J. S., Leng Q., Zhao Q., Watson D. K., Li R. RT EAPII interacts with ETS1 and modulates its transcriptional function. RL Oncogene 22:2699-2709 (2003). RN [26]; RE0048582. RX PUBMED: 11919190. RA Czuwara-Ladykowska J., Sementchenko V. I., Watson D. K., Trojanowska M. RT Ets1 is an effector of the transforming growth factor beta (TGF-beta ) signaling pathway and an antagonist of the profibrotic effects of TGF-beta. RL J. Biol. Chem. 277:20399-20408 (2002). RN [27]; RE0054487. RX PUBMED: 17027647. RA Lim J. H., Cho J. Y., Park Y. B., Park J. W., Kwon T. K. RT ESE-3 transcription factor is involved in the expression of death receptor (DR)-5 through putative Ets sites. RL Biochem. Biophys. Res. Commun. 350:736-741 (2006). XX //