TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T10531 XX ID T10531 XX DT 10.03.2005 (created); nvo. DT 29.02.2016 (updated); ros. CO Copyright (C), QIAGEN. XX FA Egr-1 XX SY early growth response protein 1; Early Growth Responsive factor 1; Egr-1; EGR1. XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T10504 AP-2alpha; Mammalia. IN T08487 AR-isoform1; human, Homo sapiens. IN T17679 c-Myb; Mammalia. IN T10516 HIF-1alpha; Mammalia. IN T15693 Mam-1; human, Homo sapiens. IN T14104 MM-1-isoform1; human, Homo sapiens. IN T11025 NFATc1; Mammalia. IN T10303 Pax-5; Mammalia. IN T18392 pitx1; Mammalia. IN T10138 SF-1; Mammalia. IN T08326 Sp1; Mammalia. IN T22875 YAP; Mammalia. XX MX M00243 V$EGR1_01. MX M01972 V$EGR1_02. MX M07597 V$EGR1_17. MX M07354 V$EGR1_Q3. MX M01873 V$EGR1_Q6. MX M08878 V$EGR_Q3. MX M00807 V$EGR_Q6. MX M00982 V$KROX_Q6. XX BS R17111. BS R25102. BS R35736. BS R35746. BS R35747. BS R35748. BS R35749. BS R35750. BS R35751. BS R35752. BS R35753. BS R35754. BS R35755. BS R35756. BS R35757. BS R35758. BS R35759. BS R71490. BS R71495. BS R71496. BS R71497. BS R71498. BS R71499. BS R71500. BS R71501. BS R71502. BS R71503. BS R71504. BS R71505. BS R71506. BS R71507. BS R71508. BS R71509. BS R71510. BS R71511. BS R71512. BS R71513. BS R71514. BS R71515. BS R37367. BS R29405. BS R62319. BS R24621. BS R24475. BS R24476. BS R37704. BS R31956. BS R41939. BS R34809. BS R24898. BS R31582. BS R24501. BS R37462. BS R57262. BS R63565. BS R25101. BS R24219. BS R23848. BS R66149. BS R66151. BS R66152. BS R71342. BS R42483. BS R30577. BS R36899. BS R58750. BS R65494. BS R65496. BS R65498. BS R31585. BS R33390. BS R24789. BS R24208. BS R24825. BS R24447. BS R67604. BS R22991. BS R21427. BS R21428. BS R33614. BS R34788. BS R34789. BS R34791. XX DR TRANSPATH: MO000047067. XX RN [1]; RE0015446. RX PUBMED: 10082522. RA Tremblay J. J., Drouin J. RT Egr-1 is a downstream effector of GnRH and synergizes by direct interaction with Ptx1 and SF-1 to enhance uteinizing hormone beta gene transcription RL Mol. Cell. Biol. 19:2567-2576 (1999). RN [2]; RE0016661. RX PUBMED: 10318795. RA Dorn C., Ou Q., Svaren J., Crawford P. A., Sadovsky Y. RT Activation of luteinizing hormone beta gene by gonadotropin-releasing hormone requires the synergy of early growth response-1 and steroidogenic factor-1. RL J. Biol. Chem. 274:13870-13876 (1999). RN [3]; RE0017905. RX PUBMED: 11328855. RA Quirk C. C., Lozada K. L., Keri R. A., Nilson J. H. RT A single Pitx1 binding site is essential for activity of the LHbeta promoter in transgenic mice RL Mol. Endocrinol. 15:734-746 (2001). RN [4]; RE0024046. RX PUBMED: 12385031. RA Castellanos Mdel C., Lopez-Giral S., Lopez-Cabrera M., de Landazuri M. O. RT Multiple cis-acting elements regulate the expression of the early T cell activation antigen CD69. RL Eur. J. Immunol. 32:3108-3117 (2002). RN [5]; RE0024908. RX PUBMED: 11956220. RA Wong W. K., Ou X. M., Chen K., Shih J. C. RT Activation of human monoamine oxidase B gene expression by a protein kinase C MAPK signal transduction pathway involves c-Jun and Egr-1. RL J. Biol. Chem. 277:22222-22230 (2002). RN [6]; RE0025869. RX PUBMED: 15077182. RA Nandan M. O., Yoon H. S., Zhao W., Ouko L. A., Chanchevalap S., Yang V. W. RT Kruppel-like factor 5 mediates the transforming activity of oncogenic H-Ras. RL Oncogene 23:3404-13 (2004). RN [7]; RE0027084. RX PUBMED: 10202038. RA Fitzgerald K. A., O'Neill L. A. RT Characterization of CD44 induction by IL-1: a critical role for Egr-1. RL J. Immunol. 162:4920-7 (1999). RN [8]; RE0027306. RX PUBMED: 11113178. RA Tsuruzoe K., Emkey R., Kriauciunas K. M., Ueki K., Kahn C. R. RT Insulin receptor substrate 3 (IRS-3) and IRS-4 impair IRS-1- and IRS-2-mediated signaling RL Mol. Cell. Biol. 21:26-38 (2001). RN [9]; RE0028785. RX PUBMED: 11502738. RA Guillemot L., Levy A., Raymondjean M., Rothhut B. RT Angiotensin ii-induced transcriptional activation of the cyclin d1 gene is mediated by egr-1 in cho-at1a cells. RL J. Biol. Chem. 276:39394-403 (2001). RN [10]; RE0028908. RX PUBMED: 9819371. RA Srivastava S., Weitzmann M. N., Kimble R. B., Rizzo M., Zahner M., Milbrandt J., Ross F. P., Pacifici R. RT Estrogen blocks M-CSF gene expression and osteoclast formation by regulating phosphorylation of Egr-1 and its interaction with Sp-1. RL J. Clin. Invest. 102:1850-9 (1998). RN [11]; RE0029876. RX PUBMED: 12517959. RA Bek M. J., Reinhardt H. C., Fischer K. G., Hirsch J. R., Hupfer C., Dayal E., Pavenstadt H. RT Up-regulation of early growth response gene-1 via the CXCR3 receptor induces reactive oxygen species and inhibits Na+/K+-ATPase activity in an immortalized human proximal tubule cell line. RL J. Immunol. 170:931-40 (2003). RN [12]; RE0030513. RX PUBMED: 12670907. RA Recio J. A., Merlino G. RT Hepatocyte growth factor/scatter factor induces feedback up-regulation of CD44v6 in melanoma cells through Egr-1. RL Cancer Res. 63:1576-82 (2003). RN [13]; RE0031232. RX PUBMED: 11520792. RA Guha M., O'Connell M. A., Pawlinski R., Hollis A., McGovern P., Yan S. F., Stern D., Mackman N. RT Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression. RL Blood 98:1429-39 (2001). RN [14]; RE0031685. RX PUBMED: 12764151. RA Laszlo G. S., Nathanson N. M. RT Src family kinase-independent signal transduction and gene induction by leukemia inhibitory factor. RL J. Biol. Chem. 278:27750-7 (2003). RN [15]; RE0031689. RX PUBMED: 14522979. RA de Mestre A. M., Khachigian L. M., Santiago F. S., Staykova M. A., Hulett M. D. RT Regulation of inducible heparanase gene transcription in activated T cells by early growth response 1. RL J. Biol. Chem. 278:50377-85 (2003). RN [16]; RE0032757. RX PUBMED: 12393577. RA Wu S. Q., Minami T., Donovan D. J., Aird W. C. RT The proximal serum response element in the Egr-1 promoter mediates response to thrombin in primary human endothelial cells. RL Blood 100:4454-4461 (2002). RN [17]; RE0032766. RX PUBMED: 13679060. RA Khomenko T., Deng X., Jadus M. R., Szabo S. RT Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa. RL Biochem. Biophys. Res. Commun. 309:910-6 (2003). RN [18]; RE0033066. RX PUBMED: 9795195. RA Wong D. L., Siddall B. J., Ebert S. N., Bell R. A., Her S. RT Phenylethanolamine N-methyltransferase gene expression: synergistic activation by Egr-1, AP-2 and the glucocorticoid receptor. RL Brain Res. Mol. Brain Res. 61:154-61 (1998). RN [19]; RE0033358. RX PUBMED: 15225550. RA Yu J., de Belle I., Liang H., Adamson E. D. RT Coactivating factors p300 and CBP are transcriptionally crossregulated by Egr1 in prostate cells, leading to divergent responses. RL Mol. Cell 15:83-94 (2004). RN [20]; RE0034382. RX PUBMED: 15231710. RA Tell G., Pines A., Arturi F., Cesaratto L., Adamson E., Puppin C., Presta I., Russo D., Filetti S., Damante G. RT Control of phosphatase and tensin homolog (PTEN) gene expression in normal and neoplastic thyroid cells. RL Endocrinology 145:4660-6 (2004). RN [21]; RE0034394. RX PUBMED: 12384223. RA Al-Sarraj A., Thiel G. RT Substance P induced biosynthesis of the zinc finger transcription factor Egr-1 in human glioma cells requires activation of the epidermal growth factor receptor and of extracellular signal-regulated protein kinase. RL Neurosci. Lett. 332:111-4 (2002). RN [22]; RE0034395. RX PUBMED: 12618431. RA Rolli-Derkinderen M., Machavoine F., Baraban J. M., Grolleau A., Beretta L., Dy M. RT ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1. RL J. Biol. Chem. 278:18859-67 (2003). RN [23]; RE0034614. RX PUBMED: 11591707. RA Zhang T., Wolfe M. W., Roberson M. S. RT An early growth response protein (Egr) 1 cis-element is required for gonadotropin-releasing hormone-induced mitogen-activated protein kinase phosphatase 2 gene expression. RL J. Biol. Chem. 276:45604-13 (2001). RN [24]; RE0034678. RX PUBMED: 14720220. RA Choi S. Y., Hwang J. J., Koh J. Y. RT NR2A induction and NMDA receptor-dependent neuronal death by neurotrophin-4/5 in cortical cell culture. RL J. Neurochem 88:708-16 (2004). RN [25]; RE0037298. RX PUBMED: 12034740. RA Naraba H., Yokoyama C., Tago N., Murakami M., Kudo I., Fueki M., Oh-ishi S., Tanabe T. RT Transcriptional regulation of the membrane-associated prostaglandin E2 synthase gene. Essential role of the transcription factor Egr-1 RL J. Biol. Chem. 277:28601-8 (2002). RN [26]; RE0037299. RX PUBMED: 14722058. RA Subbaramaiah K., Yoshimatsu K., Scherl E., Das K. M., Glazier K. D., Golijanin D., Soslow R. A., Tanabe T., Naraba H., Dannenberg A. J. RT Microsomal prostaglandin E synthase-1 is overexpressed in inflammatory bowel disease. Evidence for involvement of the transcription factor Egr-1 RL J. Biol. Chem. 279:12647-58 (2004). RN [27]; RE0037809. RX PUBMED: 7523382. RA Henderson S. A., Lee P. H., Aeberhard E. E., Adams J. W., Ignarro L. J., Murphy W. J., Sherman M. P. RT Nitric oxide reduces early growth response-1 gene expression in rat lung macrophages treated with interferon-gamma and lipopolysaccharide RL J. Biol. Chem. 269:25239-42 (1994). RN [28]; RE0038727. RX PUBMED: 12379479. RA Bae M. H., Jeong C. H., Kim S. H., Bae M. K., Jeong J. W., Ahn M. Y., Bae S. K., Kim N. D., Kim C. W., Kim K. R., Kim K. W. RT Regulation of Egr-1 by association with the proteasome component C8 RL Biochim. Biophys. Acta 1592:163-7 (2002). RN [29]; RE0038744. RX PUBMED: 12456801. RA Raychowdhury R., Schafer G., Fleming J., Rosewicz S., Wiedenmann B., Wang T. C., Hocker M. RT Interaction of early growth response protein 1 (Egr-1), specificity protein 1 (Sp1), and cyclic adenosine 3'5'-monophosphate response element binding protein (CREB) at a proximal response element is critical for gastrin-dependent activation of the chromogranin A promoter RL Mol. Endocrinol. 16:2802-18 (2002). RN [30]; RE0039953. RX PUBMED: 12562764. RA de Belle I., Wu J. X., Sperandio S., Mercola D., Adamson E. D. RT In vivo cloning and characterization of a new growth suppressor protein TOE1 as a direct target gene of Egr1 RL J. Biol. Chem. 278:14306-12 (2003). RN [31]; RE0040023. RX PUBMED: 8036026. RA Vara Prasad M. V., Shore S. K., Dhanasekaran N. RT Activated mutant of G alpha 13 induces Egr-1, c-fos, and transformation in NIH 3T3 cells RL Oncogene 9:2425-9 (1994). RN [32]; RE0040556. RX PUBMED: 12427732. RA Borchert A., Savaskan N. E., Kuhn H. RT Regulation of expression of the phospholipid hydroperoxide/sperm nucleus glutathione peroxidase gene. Tissue-specific expression pattern and identification of functional cis- and trans-regulatory elements RL J. Biol. Chem. 278:2571-80 (2003). RN [33]; RE0041436. RX PUBMED: 11160302. RA Li Z., He L., Wilson K., Roberts D. RT Thrombospondin-1 inhibits TCR-mediated T lymphocyte early activation RL J. Immunol. 166:2427-36 (2001). RN [34]; RE0041706. RX PUBMED: 11327726. RA Houston P., Campbell C. J., Svaren J., Milbrandt J., Braddock M. RT The transcriptional corepressor NAB2 blocks Egr-1-mediated growth factor activation and angiogenesis RL Biochem. Biophys. Res. Commun. 283:480-6 (2001). RN [35]; RE0041708. RX PUBMED: 12427750. RA Lucerna M., Mechtcheriakova D., Kadl A., Schabbauer G., Schafer R., Gruber F., Koshelnick Y., Muller H. D., Issbrucker K., Clauss M., Binder B. R., Hofer E. RT NAB2, a corepressor of EGR-1, inhibits vascular endothelial growth factor-mediated gene induction and angiogenic responses of endothelial cells RL J. Biol. Chem. 278:11433-40 (2003). RN [36]; RE0041744. RX PUBMED: 9774344. RA Svaren J., Sevetson B. R., Golda T., Stanton J. J., Swirnoff A. H., Milbrandt J. RT Novel mutants of NAB corepressors enhance activation by Egr transactivators RL EMBO J. 17:6010-9 (1998). RN [37]; RE0043167. RX PUBMED: 9918562. RA Portier M., Rinaldi-Carmona M., Pecceu F., Combes T., Poinot-Chazel C., Calandra B., Barth F., Le Fur G., Casellas P. RT SR 144528, an antagonist for the peripheral cannabinoid receptor that behaves as an inverse agonist RL J. Pharmacol. Exp. Ther. 288:582-9 (1999). RN [38]; RE0043247. RX PUBMED: 9528972. RA Gong T. W., Meyer D. J., Liao J., Hodge C. L., Campbell G. S., Wang X., Billestrup N., Carter-Su C., Schwartz J. RT Regulation of glucose transport and c-fos and egr-1 expression in cells with mutated or endogenous growth hormone receptors RL Endocrinology 139:1863-71 (1998). RN [39]; RE0045090. RX PUBMED: 8163680. RA Hu R. M., Levin E. R. RT Astrocyte growth is regulated by neuropeptides through Tis 8 and basic fibroblast growth factor RL J. Clin. Invest. 93:1820-7 (1994). RN [40]; RE0045108. RX PUBMED: 1939108. RA Qureshi S. A., Rim M., Bruder J., Kolch W., Rapp U., Sukhatme V. P., Foster D. A. RT An inhibitory mutant of c-Raf-1 blocks v-Src-induced activation of the Egr-1 promoter RL J. Biol. Chem. 266:20594-7 (1991). RN [41]; RE0045113. RX PUBMED: 10339488. RA Mechtcheriakova D., Wlachos A., Holzmuller H., Binder B. R., Hofer E. RT Vascular endothelial cell growth factor-induced tissue factor expression in endothelial cells is mediated by EGR-1 RL Blood 93:3811-23 (1999). RN [42]; RE0045178. RX PUBMED: 14699164. RA Gillian A. L., Svaren J. RT The Ddx20/DP103 dead box protein represses transcriptional activation by Egr2/Krox-20 RL J. Biol. Chem. 279:9056-63 (2004). RN [43]; RE0045347. RX PUBMED: 11511524. RA Maehara K., Oh-Hashi K., Isobe K. i. RT Early growth-responsive-1-dependent manganese superoxide dismutase gene transcription mediated by platelet-derived growth factor RL FASEB J. 15:2025-6 (2001). RN [44]; RE0045351. RX PUBMED: 11781575. RA Virolle T., Adamson E. D., Baron V., Birle D., Mercola D., Mustelin T., de Belle I. RT The Egr-1 transcription factor directly activates PTEN during irradiation-induced signalling RL Nat. Cell Biol. 3:1124-8 (2001). RN [45]; RE0045354. RX PUBMED: 7651617. RA Keefe K. A., Gerfen C. R. RT D1-D2 dopamine receptor synergy in striatum: effects of intrastriatal infusions of dopamine agonists and antagonists on immediate early gene expression RL Neuroscience 66:903-13 (1995). RN [46]; RE0045355. RX PUBMED: 10363818. RA Steiner H., Gerfen C. R. RT Enkephalin regulates acute D2 dopamine receptor antagonist-induced immediate-early gene expression in striatal neurons RL Neuroscience 88:795-810 (1999). RN [47]; RE0045359. RX PUBMED: 1417981. RA Hass R., Brach M., Gunji H., Kharbanda S., Kufe D. RT Inhibition of EGR-1 and NF-kappa B gene expression by dexamethasone during phorbol ester-induced human monocytic differentiation RL Biochem. Pharmacol. 44:1569-76 (1992). RN [48]; RE0045360. RX PUBMED: 10792003. RA Cenci S., Weitzmann M. N., Gentile M. A., Aisa M. C., Pacifici R. RT M-CSF neutralization and egr-1 deficiency prevent ovariectomy-induced bone loss RL J. Clin. Invest. 105:1279-87 (2000). RN [49]; RE0045362. RX PUBMED: 12457461. RA Fu M., Zhang J., Lin Y., Zhu X., Zhao L., Ahmad M., Ehrengruber M. U., Chen Y. E. RT Early stimulation and late inhibition of peroxisome proliferator-activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads RL Biochem. J. 370:1019-25 (2003). RN [50]; RE0045367. RX PUBMED: 9933644. RA Liu C., Yao J., de Belle I., Huang R. P., Adamson E., Mercola D. RT The transcription factor EGR-1 suppresses transformation of human fibrosarcoma HT1080 cells by coordinated induction of transforming growth factor-beta1, fibronectin, and plasminogen activator inhibitor-1 RL J. Biol. Chem. 274:4400-11 (1999). RN [51]; RE0045368. RX PUBMED: 10783396. RA Liu C., Yao J., Mercola D., Adamson E. RT The transcription factor EGR-1 directly transactivates the fibronectin gene and enhances attachment of human glioblastoma cell line U251 RL J. Biol. Chem. 275:20315-23 (2000). RN [52]; RE0045369. RX PUBMED: 9727068. RA Greenbaum L. E., Li W., Cressman D. E., Peng Y., Ciliberto G., Poli V., Taub R. RT CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy RL J. Clin. Invest. 102:996-1007 (1998). RN [53]; RE0045375. RX PUBMED: 15365258. RA Shin S. Y., Kim C. G., Hong D. D., Kim J. H., Lee Y. H. RT Implication of Egr-1 in trifluoperazine-induced growth inhibition in human U87MG glioma cells RL Exp. Mol. Med. 36:380-6 (2004). RN [54]; RE0045387. RX PUBMED: 12165491. RA Bettini M., Xi H., Milbrandt J., Kersh G. J. RT Thymocyte development in early growth response gene 1-deficient mice RL J. Immunol. 169:1713-20 (2002). RN [55]; RE0045389. RX PUBMED: 10487857. RA Kelley K. A., Ho L., Winger D., Freire-Moar J., Borelli C. B., Aisen P. S., Pasinetti G. M. RT Potentiation of excitotoxicity in transgenic mice overexpressing neuronal cyclooxygenase-2 RL Am. J. Pathol. 155:995-1004 (1999). RN [56]; RE0045391. RX PUBMED: 11948693. RA Kaufmann K., Thiel G. RT Epidermal growth factor and thrombin induced proliferation of immortalized human keratinocytes is coupled to the synthesis of Egr-1, a zinc finger transcriptional regulator RL J. Cell. Biochem. 85:381-91 (2002). RN [57]; RE0045392. RX PUBMED: 10510289. RA Solow B. T., Derrien A., Smith J. A., Jarett L., Harada S. RT Angiotensin II inhibits insulin-induced egr-1 expression in mesangial cells RL Arch. Biochem. Biophys. 370:308-13 (1999). RN [58]; RE0045393. RX PUBMED: 9032279. RA Bruning J. C., Winnay J., Cheatham B., Kahn C. R. RT Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells RL Mol. Cell. Biol. 17:1513-21 (1997). RN [59]; RE0045396. RX PUBMED: 8398902. RA Liu J., Shoyab M., Grove R. I. RT Induction of Egr-1 by oncostatin M precedes up-regulation of low density lipoprotein receptors in HepG2 cells RL Cell Growth Differ. 4:611-6 (1993). RN [60]; RE0045397. RX PUBMED: 12374773. RA Shin S. Y., Ko J., Chang J. S., Min do S., Choi C., Bae S. S., Kim M. J., Hyun D. S., Kim J. H., Han M. Y., Kim Y. H., Kim Y. S., Na D. S., Suh P. G., Lee Y. H. RT Negative regulatory role of overexpression of PLC gamma 1 in the expression of early growth response 1 gene in rat 3Y1 fibroblasts RL FASEB J. 16:1504-14 (2002). RN [61]; RE0045398. RX PUBMED: 8977235. RA Tian S. S., Tapley P., Sincich C., Stein R. B., Rosen J., Lamb P. RT Multiple signaling pathways induced by granulocyte colony-stimulating factor involving activation of JAKs, STAT5, and/or STAT3 are required for regulation of three distinct classes of immediate early genes RL Blood 88:4435-44 (1996). RN [62]; RE0045401. RX PUBMED: 12629205. RA Krones-Herzig A., Adamson E., Mercola D. RT Early growth response 1 protein, an upstream gatekeeper of the p53 tumor suppressor, controls replicative senescence RL Proc. Natl. Acad. Sci. USA 100:3233-8 (2003). RN [63]; RE0045402. RX PUBMED: 11007921. RA Erickson-Miller C. L., Pelus L. M., Lord K. A. RT Signaling induced by erythropoietin and stem cell factor in UT-7/Epo cells: transient versus sustained proliferation RL Stem Cells 18:366-73 (2000). RN [64]; RE0045407. RX PUBMED: 15247255. RA Midgley V. C., Khachigian L. M. RT Fibroblast growth factor-2 induction of platelet-derived growth factor-C chain transcription in vascular smooth muscle cells is ERK-dependent but not JNK-dependent and mediated by Egr-1 RL J. Biol. Chem. 279:40289-95 (2004). RN [65]; RE0045409. RX PUBMED: 9539784. RA Lotem J., Sachs L. RT Different mechanisms for suppression of apoptosis by cytokines and calcium mobilizing compounds RL Proc. Natl. Acad. Sci. USA 95:4601-6 (1998). RN [66]; RE0045418. RX PUBMED: 1741159. RA Qureshi S. A., Rim M. H., Alexandropoulos K., Berg K., Sukhatme V. P., Foster D. A. RT Sustained induction of egr-1 by v-src correlates with a lack of fos-mediated repression of the egr-1 promoter RL Oncogene 7:121-5 (1992). RN [67]; RE0045429. RX PUBMED: 10395064. RA Shamim A., Pelzer T., Grohe C., Neyses L. RT Induction of Egr-1 mRNA and protein by endothelin 1, angiotensin II and norepinephrine in neonatal cardiac myocytes RL Mol. Cell. Biochem. 195:11-7 (1999). RN [68]; RE0045430. RX PUBMED: 9042572. RA Humblot N., Esteve L., Burgun C., Aunis D., Zwiller J. RT 5-Hydroxytryptamine induces TIS8/egr-1 and c-fos expression in PC12 cells. Involvement of tyrosine protein phosphorylation RL Eur. J. Neurosci. 9:84-92 (1997). RN [69]; RE0045443. RX PUBMED: 11403719. RA Harada S., Esch G. L., Holgado-Madruga M., Wong A. J. RT Grb-2-associated binder-1 is involved in insulin-induced egr-1 gene expression through its phosphatidylinositol 3'-kinase binding site RL DNA Cell Biol. 20:223-9 (2001). RN [70]; RE0045444. RX PUBMED: 12560508. RA Davis W. Jr, Chen Z. J., Ile K. E., Tew K. D. RT Reciprocal regulation of expression of the human adenosine 5'-triphosphate binding cassette, sub-family A, transporter 2 (ABCA2) promoter by the early growth response-1 (EGR-1) and Sp-family transcription factors RL Nucleic Acids Res. 31:1097-107 (2003). RN [71]; RE0045446. RX PUBMED: 14662774. RA Baek S. J., Kim J. S., Nixon J. B., DiAugustine R. P., Eling T. E. RT Expression of NAG-1, a transforming growth factor-beta superfamily member, by troglitazone requires the early growth response gene EGR-1 RL J. Biol. Chem. 279:6883-92 (2004). RN [72]; RE0045644. RX PUBMED: 11870074. RA Lei N., Heckert L. L. RT Sp1 and Egr1 regulate transcription of the Dmrt1 gene in Sertoli cells RL Biol. Reprod. 66:675-84 (2002). RN [73]; RE0046065. RX PUBMED: 8955189. RA Almendro N., Bellon T., Rius C., Lastres P., Langa C., Corbi A., Bernabeu C. RT Cloning of the human platelet endothelial cell adhesion molecule-1 promoter and its tissue-specific expression. Structural and functional characterization RL J. Immunol. 157:5411-21 (1996). RN [74]; RE0046203. RX PUBMED: 14525948. RA Tsugawa K., Jones M. K., Akahoshi T., Moon W. S., Maehara Y., Hashizume M., Sarfeh I. J., Tarnawski A. S. RT Abnormal PTEN expression in portal hypertensive gastric mucosa: a key to impaired PI 3-kinase/Akt activation and delayed injury healing? RL FASEB J. 17:2316-8 (2003). RN [75]; RE0046209. RX PUBMED: 9025067. RA Erno H., Kury P., Botteri F. M., Monard D. RT A Krox binding site regulates protease nexin-1 promoter activity in embryonic heart, cartilage and parts of the nervous system RL Mech. Dev. 60:139-50 (1996). RN [76]; RE0046210. RX PUBMED: 10075671. RA Lai C. F., Ripperger J., Wang Y., Kim H., Hawley R. B., Baumann H. RT The STAT3-independent signaling pathway by glycoprotein 130 in hepatic cells RL J. Biol. Chem. 274:7793-802 (1999). RN [77]; RE0046221. RX PUBMED: 10866682. RA Tourtellotte W. G., Nagarajan R., Bartke A., Milbrandt J. RT Functional compensation by egr4 in Egr1-dependent luteinizing hormone regulation and leydig cell steroidogenesis RL Mol. Cell. Biol. 20:5261-8 (2000). RN [78]; RE0046235. RX PUBMED: 9858508. RA Dinkel A., Warnatz K., Ledermann B., Rolink A., Zipfel P. F., Burki K., Eibel H. RT The transcription factor early growth response 1 (Egr-1) advances differentiation of pre-B and immature B cells RL J. Exp. Med. 188:2215-24 (1998). RN [79]; RE0046250. RX PUBMED: 8845164. RA Rusanescu G., Qi H., Thomas S. M., Brugge J. S., Halegoua S. RT Calcium influx induces neurite growth through a Src-Ras signaling cassette RL Neuron 15:1415-25 (1995). RN [80]; RE0049003. RX PUBMED: 12890669. RA Yang S. Z., Abdulkadir S. A. RT Early growth response gene 1 modulates androgen receptor signaling in prostate carcinoma cells. RL J. Biol. Chem. 278:39906-39911 (2003). RN [81]; RE0049041. RX PUBMED: 11682622. RA Curtin D., Jenkins S., Farmer N., Anderson A. C., Haisenleder D. J., Rissman E., Wilson E. M., Shupnik M. A. RT Androgen suppression of GnRH-stimulated rat LHbeta gene transcription occurs through Sp1 sites in the distal GnRH-responsive promoter region. RL Mol. Endocrinol. 15:1906-1917 (2001). RN [82]; RE0054991. RX PUBMED: 8662759. RA Jain N., Mahendran R., Philp R., Guy G. R., Tan Y. H., Cao X. RT Casein kinase II associates with Egr-1 and acts as a negative modulator of its DNA binding and transcription activities in NIH 3T3 cells. RL J. Biol. Chem. 271:13530-13536 (1996). RN [83]; RE0064443. RX PUBMED: 17244763. RA Salisbury T. B., Binder A. K., Grammer J. C., Nilson J. H. RT Maximal activity of the luteinizing hormone beta-subunit gene requires beta-catenin. RL Mol. Endocrinol. 21:963-971 (2007). RN [84]; RE0064955. RX PUBMED: 17299135. RA Lawson M. A., Tsutsumi R., Zhang H., Talukdar I., Butler B. K., Santos S. J., Mellon P. L., Webster N. J. 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