AC T15693
XX
ID T15693
XX
DT 04.03.2009 (created); pum.
DT 21.07.2014 (updated); yre.
CO Copyright (C), QIAGEN.
XX
FA Mam-1
XX
SY FLJ53540; KIAA0200; Mam-1; Mam1; MAML1; mastermind-like 1; mastermind-like 1 (Drosophila).
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
GE G014447 MAML1; HGNC: MAML1.
XX
SZ 1016 AA; 108.0 kDa (cDNA) (calc.).
XX
SQ MVLPTCPMAEFALPRHSAVMERLRRRIELCRRHHSTCEARYEAVSPERLELERQHTFALH
SQ QRCIQAKAKRAGKHRQPPAATAPAPAAPAPRLDAADGPEHGRPATHLHDTVKRNLDSATS
SQ PQNGDQQNGYGDLFPGHKKTRREAPLGVAISSNGLPPASPLGQSDKPSGADALQSSGKHS
SQ LGLDSLNKKRLADSSLHLNGGSNPSESFPLSLNKELKQEPVEDLPCMITGTVGSISQSNL
SQ MPDLNLNEQEWKELIEELNRSVPDEDMKDLFNEDFEEKKDPESSGSATQTPLAQDINIKT
SQ EFSPAAFEQEQLGSPQVRAGSAGQTFLGPSSAPVSTDSPSLGGSQTLFHTSGQPRADNPS
SQ PNLMPASAQAQNAQRALAGVVLPSQGPGGASELSSAHQLQQIAAKQKREQMLQNPQQATP
SQ APAPGQMSTWQQTGPSHSSLDVPYPMEKPASPSSYKQDFTNSKLLMMPSVNKSSPRPGGP
SQ YLQPSHVNLLSHQPPSNLNQNSANNQGSVLDYGNTKPLSHYKADCGQGSPGSGQSKPALM
SQ AYLPQQLSHISHEQNSLFLMKPKPGNMPFRSLVPPGQEQNPSSVPVQAQATSVGTQPPAV
SQ SVASSHNSSPYLSSQQQAAVMKQHQLLLDQQKQREQQQKHLQQQQFLQRQQHLLAEQEKQ
SQ QFQRHLTRPPPQYQDPTQGSFPQQVGQFTGSSAAVPGMNTLGPSNSSCPRVFPQAGNLMP
SQ MGPGHASVSSLPTNSGQQDRGVAQFPGSQNMPQSSLYGMASGITQIVAQPPPQATNGHAH
SQ IPRQTNVGQNTSVSAAYGQNSLGSSGLSQQHNKGTLNPGLTKPPVPRVSPAMGGQNSSWQ
SQ HQGMPNLSGQTPGNSNVSPFTAASSFHMQQQAHLKMSSPQFSQAVPNRPMAPMSSAAAVG
SQ SLLPPVSAQQRTSAPAPAPPPTAPQQGLPGLSPAGPELGAFSQSPASQMGGRAGLHCTQA
SQ YPVRTAGQELPFAYSGQPGGSGLSSVAGHTDLIDSLLKNRTSEEWMSDLDDLLGSQ
XX
SC translated from EMBL #D83785
XX
FT 10 880 
PF00478; IMP dehydrogenase / GMP reductase domain.
XX
IN T10531 Egr-1; Mammalia.
IN T16105 NICD1; human, Homo sapiens.
IN T01616 RBPJK; human, Homo sapiens.
XX
DR TRANSPATH: MO000154180.
DR EMBL: D83785; HSD7851.
DR UniProtKB: Q92585; Q92585.
XX
RN [1]; RE0017820.
RX PUBMED: 8724849.
RA Nagase T., Seki N., Ishikawa K., Tanaka A., Nomura N.
RT Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.
RL DNA Res. 3:17-24 (1996).
RN [2]; RE0017821.
RX PUBMED: 11101851.
RA Wu L., Aster J. C., Blacklow S. C., Lake R., Artavanis-Tsakonas S., Griffin J. D.
RT MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.
RL Nat. Genet. 26:484-489 (2000).
RN [3]; RE0055718.
RX PUBMED: 16530044.
RA Nam Y., Sliz P., Song L., Aster J. C., Blacklow S. C.
RT Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
RL Cell 124:973-983 (2006).
XX
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