AC T16105
XX
ID T16105
XX
DT 25.04.2007 (created); sri.
DT 27.04.2010 (updated); pum.
CO Copyright (C), QIAGEN.
XX
FA NICD1
XX
SY NIC-1; Notch 1 intracellular domain; Notch-intracellular-domain.
XX
OS human, Homo sapiens
OC eukaryota; animalia; metazoa; chordata; vertebrata; tetrapoda; mammalia; eutheria; primates
XX
SZ 803 AA; 85.9 kDa (cDNA) (calc.).
XX
SQ GVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNASDGALMDDNQNE
SQ WGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAPTPPQGEVDADCM
SQ DVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASLHNQTDRTGETAL
SQ HLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRATDLDARM
SQ HDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNNVDAAVVLLKNGA
SQ NKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQERMHHDIVRL
SQ LDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRKPSSKGLACGSKE
SQ AKDLKARRKKSQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLPSPFQQSPSVPLN
SQ HLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVASGTSTVLGSSSGG
SQ ALNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAPSLQHGMVGPLHS
SQ SLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPANIQQQQSLQPPP
SQ PPPQPHLGVSSAASGHLGRSFLSGEPSQADVQPLGPSSLAVHTILPQESPALPTSLPSSL
SQ VPPVTAAQFLTPPSQHSYSSPVDNTPSHQLQVPEHPFLTPSPESPDQWSSSSPHSNVSDW
SQ SEGVSSPPTSMQSQIARIPEAFK
XX
SC translated from EMBL:AF308602
XX
IN T08597 alpha-enolase-isoform2; human, Homo sapiens.
IN T24854 alpha-enolase; human, Homo sapiens.
IN T15693 Mam-1; human, Homo sapiens.
IN T01616 RBPJK; human, Homo sapiens.
IN T08660 YY1; human, Homo sapiens.
XX
BS R28183.
XX
DR TRANSPATH: MO000105099.
XX
RN [1]; RE0049791.
RX PUBMED: 16234243.
RA Kim S. H., Sisodia S. S.
RT Evidence that the "NF" motif in transmembrane domain 4 of presenilin 1 is critical for binding with PEN-2.
RL J. Biol. Chem. 280:41953-41966 (2005).
RN [2]; RE0055718.
RX PUBMED: 16530044.
RA Nam Y., Sliz P., Song L., Aster J. C., Blacklow S. C.
RT Structural basis for cooperativity in recruitment of MAML coactivators to Notch transcription complexes.
RL Cell 124:973-983 (2006).
RN [3]; RE0062604.
RX PUBMED: 18490439.
RA Hsu K. W., Hsieh R. H., Lee Y. H., Chao C. H., Wu K. J., Tseng M. J., Yeh T. S.
RT The activated Notch1 receptor cooperates with alpha-enolase and MBP-1 in modulating c-myc activity.
RL Mol. Cell. Biol. 28:4829-4842 (2008).
RN [4]; RE0066615.
RX PUBMED: 16990763.
RA Weerkamp F., Luis T. C., Naber B. A., Koster E. E., Jeannotte L., van Dongen J. J., Staal F. J.
RT Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program.
RL Leukemia 20:1967-1977 (2006).
XX
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