AC T22875
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ID T22875
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DT 10.03.2005 (created); nvo.
DT 23.04.2014 (updated); yre.
CO Copyright (C), QIAGEN.
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FA YAP
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SY YAP; yAP1; YAP2; YAP65; Yes-associated protein 1, 65kDa; yes-associated protein 2; YKI.
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OS Mammalia
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia
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IN T09552 AML3; Mammalia.
IN T17641 ASPP2; Mammalia.
IN T10531 Egr-1; Mammalia.
IN T16759 p73; Mammalia.
IN T03885 Smad1; human, Homo sapiens.
IN T10783 Smad1; Mammalia.
IN T17891 TEF-3; Mammalia.
IN T29454 TEF-4; Mammalia.
IN T10474 TEF-5; Mammalia.
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DR TRANSPATH: MO000047408.
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RN [1]; RE0029914.
RX PUBMED: 12535517.
RA Basu S., Totty N. F., Irwin M. S., Sudol M., Downward J.
RT Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 14-3-3 and attenuation of p73-mediated apoptosis.
RL Mol. Cell 11:11-23 (2003).
RN [2]; RE0037214.
RX PUBMED: 7644498.
RA Chen H. I., Sudol M.
RT The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules
RL Proc. Natl. Acad. Sci. USA 92:7819-23 (1995).
RN [3]; RE0041892.
RX PUBMED: 10228168.
RA Yagi R., Chen L. F., Shigesada K., Murakami Y., Ito Y.
RT A WW domain-containing yes-associated protein (YAP) is a novel transcriptional co-activator
RL EMBO J. 18:2551-62 (1999).
RN [4]; RE0044562.
RX PUBMED: 15023535.
RA Omerovic J., Puggioni E. M., Napoletano S., Visco V., Fraioli R., Frati L., Gulino A., Alimandi M.
RT Ligand-regulated association of ErbB-4 to the transcriptional co-activator YAP65 controls transcription at the nuclear level
RL Exp. Cell Res. 294:469-79 (2004).
RN [5]; RE0050157.
RX PUBMED: 17535448.
RA Paliwal P., Radha V., Swarup G.
RT Regulation of p73 by Hck through kinase-dependent and independent mechanisms.
RL BMC Mol. Biol. 8:45 (2007).
RN [6]; RE0071731.
RX PUBMED: 18579750.
RA Zhao B., Ye X., Yu J., Li L., Li W., Li S., Yu J., Lin J. D., Wang C. Y., Chinnaiyan A. M., Lai Z. C., Guan K. L.
RT TEAD mediates YAP-dependent gene induction and growth control.
RL Genes Dev. 22:1962-1971 (2008).
RN [7]; RE0071837.
RX PUBMED: 21489991.
RA Donninger H., Allen N., Henson A., Pogue J., Williams A., Gordon L., Kassler S., Dunwell T., Latif F., Clark G. J.
RT Salvador protein is a tumor suppressor effector of RASSF1A with hippo pathway-independent functions.
RL J. Biol. Chem. 286:18483-18491 (2011).
RN [8]; RE0071891.
RX PUBMED: 21832154.
RA Paramasivam M., Sarkeshik A., Yates JR 3. r. d., Fernandes M. J., McCollum D.
RT Angiomotin family proteins are novel activators of the LATS2 kinase tumor suppressor.
RL Mol. Biol. Cell 22:3725-3733 (2011).
RN [9]; RE0071920.
RX PUBMED: 21187284.
RA Wang W., Huang J., Chen J.
RT Angiomotin-like proteins associate with and negatively regulate YAP1.
RL J. Biol. Chem. 286:4364-4370 (2011).
RN [10]; RE0072017.
RX PUBMED: 20048001.
RA Zhao B., Li L., Tumaneng K., Wang C. Y., Guan K. L.
RT A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF(beta-TRCP).
RL Genes Dev. 24:72-85 (2010).
RN [11]; RE0072967.
RX PUBMED: 21376238.
RA Schlegelmilch K., Mohseni M., Kirak O., Pruszak J., Rodriguez J. R., Zhou D., Kreger B. T., Vasioukhin V., Avruch J., Brummelkamp T. R., Camargo F. D.
RT Yap1 acts downstream of alpha-catenin to control epidermal proliferation.
RL Cell 144:782-795 (2011).
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