TRANSFAC FACTOR TABLE, Release 2017.2 - public - 2017-06-30, (C) QIAGEN

AC T11025 AS T15091. XX ID T11025 XX DT 10.03.2005 (created); nvo. DT 12.05.2016 (updated); sup. CO Copyright (C), QIAGEN. XX FA NFATc1 XX SY NF-AT2; NF-ATc1; NFAT2; NFATC; NFATC1; Nuclear Factor of Activated T-cells c; Nuclear Factor of Activated T-cells c (NF-AT2). XX OS Mammalia OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia XX IN T10346 c-Fos; Mammalia. IN T09446 c-Jun; Mammalia. IN T00241 Egr-1; human, Homo sapiens. IN T09462 Egr-1; human, Homo sapiens. IN T10531 Egr-1; Mammalia. IN T05190 Egr-4; human, Homo sapiens. IN T08705 Egr-4; human, Homo sapiens. IN T08629 GATA-4; Mammalia. IN T09447 JunD; Mammalia. IN T13783 MafB; Mammalia. IN T11024 NFATc2; Mammalia. IN T23091 p300; Mammalia. IN T10037 PU.1; Mammalia. IN T08326 Sp1; Mammalia. XX MX M07264 V$NFAT2_Q4. MX M01718 V$NFAT2_Q5. MX M07606 V$NFAT2_Q5_01. MX M07608 V$NFAT_Q3. MX M00935 V$NFAT_Q4_01. MX M00302 V$NFAT_Q6. XX BS R08188. BS R14422. BS R21079. BS R21082. BS R25248. BS R65968. BS R30940. BS R05080. BS R05081. BS R05097. BS R37146. BS R59944. BS R59951. BS R59958. BS R59960. BS R64053. XX DR TRANSPATH: MO000047277. DR TRANSCOMPEL: C00159. DR TRANSCOMPEL: C00161. DR TRANSCOMPEL: C00167. XX RN [1]; RE0022855. RX PUBMED: 10866678. RA Chow C. W., Dong C., Flavell R. A., Davis R. J. RT c-Jun NH(2)-terminal kinase inhibits targeting of the protein phosphatase calcineurin to NFATc1. RL Mol. Cell. Biol. 20:5227-5234 (2000). RN [2]; RE0030092. RX PUBMED: 12560487. RA Decker E. L., Nehmann N., Kampen E., Eibel H., Zipfel P. F., Skerka C. RT Early growth response proteins (EGR) and nuclear factors of activated T cells (NFAT) form heterodimers and regulate proinflammatory cytokine gene expression. RL Nucleic Acids Res. 31:911-21 (2003). RN [3]; RE0032766. RX PUBMED: 13679060. RA Khomenko T., Deng X., Jadus M. R., Szabo S. RT Effect of cysteamine on redox-sensitive thiol-containing proteins in the duodenal mucosa. RL Biochem. Biophys. Res. Commun. 309:910-6 (2003). RN [4]; RE0032776. RX PUBMED: 15117818. RA Kawamura T., Ono K., Morimoto T., Akao M., Iwai-Kanai E., Wada H., Sowa N., Kita T., Hasegawa K. RT Endothelin-1-dependent nuclear factor of activated T lymphocyte signaling associates with transcriptional coactivator p300 in the activation of the B cell leukemia-2 promoter in cardiac myocytes. RL Circ. Res. 94:1492-9 (2004). RN [5]; RE0033399. RX PUBMED: 15314684. RA Ikeda F., Nishimura R., Matsubara T., Tanaka S., Inoue J., Reddy S. V., Hata K., Yamashita K., Hiraga T., Watanabe T., Kukita T., Yoshioka K., Rao A., Yoneda T. RT Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation. RL J. Clin. Invest. 114:475-84 (2004). RN [6]; RE0041273. RX PUBMED: 12850144. RA Lee S. J., Lee K., Yang X., Jung C., Gardner T., Kim H. S., Jeng M. H., Kao C. RT NFATc1 with AP-3 site binding specificity mediates gene expression of prostate-specific-membrane-antigen RL J. Mol. Biol. 330:749-60 (2003). RN [7]; RE0041282. RX PUBMED: 11994444. RA Porter C. M., Clipstone N. A. RT Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells RL J. Immunol. 168:4936-45 (2002). RN [8]; RE0041298. RX PUBMED: 11435416. RA Morimoto T., Hasegawa K., Wada H., Kakita T., Kaburagi S., Yanazume T., Sasayama S. RT Calcineurin-GATA4 pathway is involved in beta-adrenergic agonist-responsive endothelin-1 transcription in cardiac myocytes RL J. Biol. Chem. 276:34983-9 (2001). RN [9]; RE0041302. RX PUBMED: 15067058. RA Patra A. K., Na S. Y., Bommhardt U. RT Active protein kinase B regulates TCR responsiveness by modulating cytoplasmic-nuclear localization of NFAT and NF-kappa B proteins RL J. Immunol. 172:4812-20 (2004). RN [10]; RE0041329. RX PUBMED: 12479813. RA Takayanagi H., Kim S., Koga T., Nishina H., Isshiki M., Yoshida H., Saiura A., Isobe M., Yokochi T., Inoue J., Wagner E. F., Mak T. W., Kodama T., Taniguchi T. RT Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts RL Dev. Cell 3:889-901 (2002). RN [11]; RE0042435. RX PUBMED: 11823475. RA Rainio E. M., Sandholm J., Koskinen P. J. RT Cutting edge: Transcriptional activity of NFATc1 is enhanced by the Pim-1 kinase RL J. Immunol. 168:1524-7 (2002). RN [12]; RE0042436. RX PUBMED: 15312161. RA Cohen T. V., Randall W. R. RT NFATc1 activates the acetylcholinesterase promoter in rat muscle RL J. Neurochem 90:1059-67 (2004). RN [13]; RE0048174. RX PUBMED: 15304486. RA Matsumoto M., Kogawa M., Wada S., Takayanagi H., Tsujimoto M., Katayama S., Hisatake K., Nogi Y. RT Essential role of p38 mitogen-activated protein kinase in cathepsin K gene expression during osteoclastogenesis through association of NFATc1 and PU.1. RL J. Biol. Chem. 279:45969-45979 (2004). RN [14]; RE0056028. RX PUBMED: 19321441. RA Feng H., Cheng T., Steer J. H., Joyce D. A., Pavlos N. J., Leong C., Kular J., Liu J., Feng X., Zheng M. H., Xu J. RT MEF2 and MITF cooperate with NFATC1 to transactivate the V-ATPase D2 promoter during rankl-induced osteoclastogenesis. RL J. Biol. Chem. 284:14667-14676 (2009). RN [15]; RE0065478. RX PUBMED: 19609356. RA Kayama H., Koga R., Atarashi K., Okuyama M., Kimura T., Mak T. W., Uematsu S., Akira S., Takayanagi H., Honda K., Yamamoto M., Takeda K. RT NFATc1 mediates Toll-like receptor-independent innate immune responses during Trypanosoma cruzi infection. RL PLoS Pathog. 5:e1000514 (2009). RN [16]; RE0067101. RX PUBMED: 20037154. RA Kim J. H., Kim K., Jin H. M., Song I., Youn B. U., Lee S. H., Choi Y., Kim N. RT Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1. RL J. Biol. Chem. 285:5224-5231 (2010). XX //